4-(4-phenoxybenzoyl)benzoyl chloride | 82745-28-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-(4-phenoxybenzoyl)benzoyl chloride
• CAS: 82745-28-6
• 化学式: C₂₀H₁₃ClO₃
• 分子量: 336.774
• InChiKey: SITZKEFXOJDPOC-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  6.2
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  4-(4-phenoxybenzoyl)benzoyl chloride 、 硫酸 、 氯化亚砜 生成 4-[4-(4-Chlorosulfonyl-phenoxy)-benzoyl]-benzoic acid
  参考文献：
  名称：

  MOSKVICHEV, YU. A.;TIMOSHENKO, G. N.;MIRONOV, G. S.;GRACHEVA, S. G.;KRYUK+, ZH. ORGAN. XIMII, 1982, 18, N 5, 1006-1010

  摘要：

  DOI：
• 作为产物：
  描述：

  4-(4-(phenoxy)benzoyl)benzoic acid 在 氯化亚砜 、 N,N-二甲基甲酰胺 作用下， 生成 4-(4-phenoxybenzoyl)benzoyl chloride
  参考文献：
  名称：

  Moskvichev, Yu.A.; Timoshenko, G.N.; Mironov, G.S., Journal of Organic Chemistry USSR (English Translation), 1982, vol. 18, p. 871 - 874

  摘要：

  DOI：

文献信息

• DISSOCIATION OF A 1,4-BIS (4-PHENOXYBENZOYL)BENZENE - LEWIS ACID COMPLEX IN AN AQUEOUS SOLUTION
  申请人：ARKEMA FRANCE

  公开号：US20180334420A1

  公开（公告）日：2018-11-22

  A method for manufacturing 1,4-bis(4-phenoxybenzoylbenzene), including: reacting terephthaloyl chloride with diphenyl ether in a reaction solvent and in the presence of a Lewis acid, so as to obtain a product mixture including a 1,4-bis(4-phenoxybenzoylbenzene)-Lewis acid complex; contacting the product mixture with an aqueous solution, so as to obtain an aqueous phase containing the Lewis acid and an organic phase containing 1,4-bis(4-phenoxybenzoylbenzene).

  一种制备1,4-双(4-苯氧基苯甲酰基苯)的方法，包括以下步骤：在反应溶剂和路易斯酸的存在下，将苯二甲醚与对苯二甲酰氯反应，从而获得包含1,4-双(4-苯氧基苯甲酰基苯)-路易斯酸复合物的产物混合物；将产物混合物与水溶液接触，从而获得含有路易斯酸的水相和含有1,4-双(4-苯氧基苯甲酰基苯)的有机相。
• [EN] METHOD FOR MANUFACTURING 1,4-BIS (4-PHENOXYBENZOYLBENZENE) IN SUPERSATURATION CONDITIONS<br/>[FR] PROCÉDÉ DE FABRICATION DE 1,4-BIS (4-PHÉNOXYBENZOYLBENZÈNE) DANS DES CONDITIONS DE SURSATURATION
  申请人：ARKEMA FRANCE

  公开号：WO2018210959A1

  公开（公告）日：2018-11-22

  The invention relates to amethod for manufacturing 1,4-bis(4-phenoxybenzoylbenzene), comprising: providing a reactant mixture comprising terephthaloyl chloride, diphenyl ether and a Lewis acid in a solvent; reacting terephthaloyl chloride with diphenyl ether, so as to obtain a product mixture comprising a 1,4-bis(4-phenoxybenzoylbenzene)- Lewis acid complex; wherein the 1,4-bis(4-phenoxybenzoylbenzene)-Lewis acid complex is dissolved in the solvent at a 1,4-bis(4-phenoxybenzoylbenzene) weight concentration in the solvent which is higher than the saturation limit of the 1,4-bis(4-phenoxybenzoylbenzene)-Lewis acid complex during at least part of the step of reacting terephthaloyl chloride with diphenyl ether.

  本发明涉及一种制造1,4-双(4-苯氧基苯甲酰基苯)的方法，包括：提供一个反应物混合物，其中包括对苯二甲酰氯、二苯醚和路易斯酸在溶剂中；将对苯二甲酰氯与二苯醚反应，从而得到一个产物混合物，其中包括1,4-双(4-苯氧基苯甲酰基苯)-路易斯酸复合物；其中1,4-双(4-苯氧基苯甲酰基苯)-路易斯酸复合物在溶剂中以1,4-双(4-苯氧基苯甲酰基苯)重量浓度高于至少部分反应对苯二甲酰氯与二苯醚的饱和限度时溶解。
• METHOD FOR MANUFACTURING 1,4-BIS (4-PHENOXYBENZOYL)BENZENE USING SUBSTANTIALLY NON-HYDROLYZED TEREPHTHALOYL CHLORIDE
  申请人：ARKEMA FRANCE

  公开号：US20180334419A1

  公开（公告）日：2018-11-22

  A method for manufacturing 1,4-bis(4-phenoxybenzoylbenzene), including: providing terephthaloyl chloride, diphenyl ether, a solvent and a Lewis acid, wherein the terephthaloyl chloride is of a purity grade such that, 10 minutes after introducing it at a reference concentration of 6.5 wt. % into said solvent, at a temperature of 20° C., a solution is obtained having a turbidity of less than 500 NTU; mixing the terephthaloyl chloride, the diphenyl ether and the solvent so as to make a reactant mixture; adding the Lewis acid to the reactant mixture so as to effect the reaction of the terephthaloyl chloride with the diphenyl ether; recovering a product mixture comprising a 1,4-bis(4-phenoxybenzoylbenzene)-Lewis acid complex.

  一种制造1,4-双(4-苯氧基苯甲酰基苯)的方法，包括：提供苯二甲醚、苯二甲酰氯、溶剂和路易斯酸，其中苯二甲酰氯的纯度等级是这样的，在将其以参考浓度6.5重量％引入所述溶剂中10分钟后，在20℃的温度下获得的溶液浑浊度小于500 NTU；混合苯二甲酰氯、苯二甲醚和溶剂以形成反应物混合物；将路易斯酸添加到反应物混合物中以使苯二甲酰氯与苯二甲醚反应；回收包含1,4-双(4-苯氧基苯甲酰基苯)-路易斯酸复合物的产物混合物。
• [EN] PURIFICATION OF 1,4-BIS (4-PHENOXYBENZOYLBENZENE) BY CENTRIFUGAL FILTRATION<br/>[FR] PURIFICATION DE 1,4-BIS (4-PHÉNOXYBENZOYLBENZÈNE) PAR FILTRATION CENTRIFUGE
  申请人：ARKEMA FRANCE

  公开号：WO2018211046A1

  公开（公告）日：2018-11-22

  The invention relates to a method for manufacturing 1,4-bis(4- phenoxybenzoylbenzene), comprising: –reacting terephthaloyl chloride with diphenyl ether in a reaction solvent and in the presence of a Lewis acid, so as to obtain a product mixture comprising a 1,4-bis(4-phenoxybenzoylbenzene)-Lewis acid complex; –putting the product mixture in contact with a protic solvent, so as to obtain a first phase containing the Lewis acid and a second phase containing 1,4-bis(4-phenoxybenzoylbenzene); –subjecting at least the second phase to a solid / liquid separation step by centrifugal filtration, so as to recover solid 1,4-bis(4- phenoxybenzoylbenzene).

  本发明涉及一种制备1,4-双(4-苯氧基苯甲酰基苯)的方法，包括以下步骤：-在反应溶剂和路易斯酸的存在下，将对苯二甲酰氯与二苯醚反应，从而得到包含1,4-双(4-苯氧基苯甲酰基苯)-路易斯酸复合物的产物混合物；-将产物混合物与质子溶剂接触，从而得到包含路易斯酸的第一相和包含1,4-双(4-苯氧基苯甲酰基苯)的第二相；-通过离心过滤对至少第二相进行固液分离步骤，以回收固体1,4-双(4-苯氧基苯甲酰基苯)。
• [EN] RIPENING OF 1,4-BIS (4-PHENOXYBENZOYL) BENZENE<br/>[FR] MATURATION DE 1,4-BIS (4-PHÉNOXYBENZOYL) BENZÈNE
  申请人：ARKEMA FRANCE

  公开号：WO2018211048A1

  公开（公告）日：2018-11-22

  The invention relates to a method for manufacturing 1,4-bis(4-phenoxybenzoylbenzene), comprising: reacting terephthaloyl chloride with diphenyl ether in a reaction solvent and in the presence of a Lewis acid, so as to obtain a product mixture comprising a 1,4-bis(4-phenoxybenzoylbenzene)-Lewis acid complex; putting the product mixturein contact with a protic solvent, so as to obtain a first phase containing the Lewis acid and a second phase containing 1,4-bis(4-phenoxybenzoylbenzene); heating at least the second phase up to a maximum temperature, followed by cooling the second phase down to a separation temperature; subjecting at least the second phase to a solid / liquid separation step at the separation temperature, so as to recover solid 1,4-bis(4-phenoxybenzoylbenzene).

  本发明涉及一种制备1,4-双(4-苯氧基苯甲酰基)苯的方法，包括以下步骤：在反应溶剂和Lewis酸的存在下，将对苯二甲酰氯与二苯醚反应，以获得包含1,4-双(4-苯氧基苯甲酰基)苯-Lewis酸复合物的产物混合物；将产物混合物与质子溶剂接触，以获得含有Lewis酸的第一相和含有1,4-双(4-苯氧基苯甲酰基)苯的第二相；将至少第二相加热至最高温度，然后将第二相冷却至分离温度；将至少第二相在分离温度下进行固体/液体分离步骤，以回收固体1,4-双(4-苯氧基苯甲酰基)苯。