Novel cyclic amino acids which are useful in preparing biologically active peptides as well as a process for the preparation of D and L enantiomers of the cyclic amino acids are described where an N-protected derivative of the racemic cyclic amino acid is treated with (-)cinchonidine and the resulting salt resolved into the desired enantiomers, as well as derivatives thereof and valuable intermediates used in the process.
描述了一种用于制备
生物活性肽的新型环状
氨基酸,以及一种制备环状
氨基酸的D和L对映体的方法,其中将外消旋环状
氨基酸的N-保护衍
生物与(-)
奎宁丁进行处理,并将生成的盐分离为所需的对映体,以及用于该过程的衍
生物和有价值的中间体。