1,5-di-O-acetyl-2,3,4,6-tetra-O-methylmannitol | 53403-07-9

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 1,5-di-O-acetyl-2,3,4,6-tetra-O-methylmannitol
• 英文别名: 1,5-di-O-acetyl-2,3,4,6-tetra-O-methyl-D-mannitol；1-O,5-O-Diacetyl-2-O,3-O,4-O,6-O-tetramethyl-D-manno-hexitol；[(2R,3R,4R,5R)-5-acetyloxy-2,3,4,6-tetramethoxyhexyl] acetate
• CAS: 53403-07-9
• 化学式: C₁₄H₂₆O₈
• 分子量: 322.356
• InChiKey: OVCJDQPBVXUBBF-AAVRWANBSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  -0.3
• 重原子数：
  22
• 可旋转键数：
  13
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  89.5
• 氢给体数：
  0
• 氢受体数：
  8

反应信息

• 作为产物：
  描述：

  (2R,3S,4R,5S,6S)-2-(hydroxymethyl)-6-(4-nitrophenoxy)oxane-3,4,5-triol 生成 1,5-di-O-acetyl-2,3,4,6-tetra-O-methylmannitol
  参考文献：
  名称：

  SHEA, ELAINE M.;CARPITA, NICHOLAS C., J. CHROMATOGR., 445,(1988) N 2, 424-428

  摘要：

  DOI：

文献信息

• A PROCESS FOR THE PREPARATION OF POLYMERIC BIOSURFACTANTS
  申请人：Council of Scientific & Industrial Research

  公开号：EP2947153A2

  公开（公告）日：2015-11-25

  The present invention relates to polymeric biosurfactants isolated from two bacterial strains of Microbacterium sp. strain BS-2 [MTCC 5822] and Brevibacillus sp. strain BS-207 [MTCC 5823]. The present invention relates to an acidic exopolysaccharide (EPS), termed Microsan, with chemical composition of glucose, mannose and glucuronic acid (β-D-glucuronyl-(1-2)-D-mannosyl-(1-4)-D-glucose) produced by Microbacterium sp. strain BS-2 and a neutral EPS, termed Brevisan, of galactomannan with galactose and mannose residues in the ratio of 1:1 produced by Brevibacillus sp. strain BS-207. Both these polysaccharides exhibited surface-active and potential antibacterial, antioxidant, anti-inflammatory, and immunomodulatory activities.

  本发明涉及从微杆菌 BS-2 株[MTCC 5822]和芽孢杆菌 BS-207 株[MTCC 5823]两株细菌中分离出来的高分子生物表面活性剂。本发明涉及一种由微细菌菌株 BS-2 产生的酸性外多糖（EPS），称为 Microsan，其化学成分为葡萄糖、甘露糖和葡萄糖醛酸（β-D-葡萄糖醛酸基-(1-2)-D-甘露糖基-(1-4)-D-葡萄糖）；以及一种由乳酸杆菌菌株 BS-207 产生的中性外多糖，称为 Brevisan，其化学成分为半乳甘露聚糖，半乳糖和甘露糖残基的比例为 1:1。这两种多糖都具有表面活性和潜在的抗菌、抗氧化、抗炎和免疫调节活性。
• Process for the preparation of polymeric biosurfactants
  申请人：COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH

  公开号：US10106627B2

  公开（公告）日：2018-10-23

  The present invention relates to polymeric biosurfactants isolated from two bacterial strains of Microbacterium sp. strain BS-2 [MTCC 5822] and Brevibacillus sp. strain BS-207 [MTCC 5823]. The present invention relates to an acidic exopolysaccharide (EPS), termed Microsan, with chemical composition of glucose, mannose and glucuronic acid (β-D-glucuronyl-(1-2)-D-mannosyl-(1-4)-D-glucose) produced by Microbacterium sp. strain BS-2 and a neutral EPS, termed Brevisan, of galactomannan with galactose and mannose residues in the ratio of 1:1 produced by Brevibacillus sp. strain BS-207. Both these polysaccharides exhibited surface-active and potential antibacterial, antioxidant, anti-inflammatory, and immunomodulatory activities.

  本发明涉及从微杆菌 BS-2 株[MTCC 5822]和芽孢杆菌 BS-207 株[MTCC 5823]两株细菌中分离出来的高分子生物表面活性剂。本发明涉及一种由微细菌菌株 BS-2 产生的酸性外多糖（EPS），称为 Microsan，其化学成分为葡萄糖、甘露糖和葡萄糖醛酸（β-D-葡萄糖醛酸基-(1-2)-D-甘露糖基-(1-4)-D-葡萄糖）；以及一种由乳酸杆菌菌株 BS-207 产生的中性外多糖，称为 Brevisan，其化学成分为半乳甘露聚糖，半乳糖和甘露糖残基的比例为 1:1。这两种多糖都具有表面活性和潜在的抗菌、抗氧化、抗炎和免疫调节活性。
• The structural elucidation of the capsular polysaccharide of Klebsiella K68
  作者：Guy G.S. Dutton、Haralambos Parolis、Lesley S. Parolis

  DOI：10.1016/s0008-6215(00)90305-7

  日期：1986.9

  The structure of the capsular polysaccharide isolated from Klebsiella K68 bacteria has been elucidated by both chemical and spectroscopic methods. The structure is of the "3 + 1" type, similar in pattern to the structures of the polysaccharides of Klebsiella K11 and K57, having a single branch point on the uronic acid. The polysaccharide is shown to consist of the following repeating unit: (Formula: see text).
• SHEA, ELAINE M.;CARPITA, NICHOLAS C., J. CHROMATOGR., 445,(1988) N 2, 424-428
  作者：SHEA, ELAINE M.、CARPITA, NICHOLAS C.

  DOI：——

  日期：——
• PROCESS FOR THE PREPARATION OF POLYMERIC BIOSURFACTANTS
  申请人：COUNCIL OF SCIENTIFIC & INDUSTRIAL RESEARCH

  公开号：US20150322173A1

  公开（公告）日：2015-11-12

  The present invention relates to polymeric biosurfactants isolated from two bacterial strains of Microbacterium sp. strain BS-2 [MTCC 5822] and Brevibacillus sp. strain BS-207 [MTCC 5823]. The present invention relates to an acidic exopolysaccharide (EPS), termed Microsan, with chemical composition of glucose, mannose and glucuronic acid (β-D-glucuronyl-(1-2)-D-mannosyl-(1-4)-D-glucose) produced by Microbacterium sp. strain BS-2 and a neutral EPS, termed Brevisan, of galactomannan with galactose and mannose residues in the ratio of 1:1 produced by Brevibacillus sp. strain BS-207. Both these polysaccharides exhibited surface-active and potential antibacterial, antioxidant, anti-inflammatory, and immunomodulatory activities.