3-(3-Methyl-4-nitrophenyl)-7-phenylfuro[2,3-f][1]benzofuran-2,6-dione | 158629-74-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 3-(3-Methyl-4-nitrophenyl)-7-phenylfuro[2,3-f][1]benzofuran-2,6-dione
• CAS: 158629-74-4
• 化学式: C₂₃H₁₃NO₆
• 分子量: 399.359
• InChiKey: GLAXECCEOMOUQZ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  30
• 可旋转键数：
  2
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.04
• 拓扑面积：
  98.4
• 氢给体数：
  0
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  3-(3-Methyl-4-nitrophenyl)-7-phenylfuro[2,3-f][1]benzofuran-2,6-dione 在 palladium/alumina air 、 氢气 、 三乙胺 作用下， 以 乙酸乙酯 为溶剂， 生成 3-(4-amino-3-methylphenyl)-7-phenyl-benzo-[1,2-b:4,5-b']-difuran-2,6-di-one
  参考文献：
  名称：

  Novel High Yielding Syntheses of Benzodifuranone Dyes Bearing Nitrogen Substituents at the 4-Position of a Pendent Phenyl Ring

  摘要：

  Otherwise inaccessible nitro benzodifuranone (BZDF) dyes are formed in good yield by treatment of 5-hydroxy-2-oxo-3-phenyl-2,3-dihydrobenzofuran either with 4NO(2)-3-R-C6H3CBrClCO2CH3 (R = H, alkyl, aryl or CO2CH3) in acetic acid. High yielding reduction of the nitro to the amino BZDF is accomplished by catalytic hydrogenation over Pd or by NaBH4/SnCl2.

  DOI：

  10.1080/00397919608003867
• 作为产物：
  描述：

  3-(4-amino-3-methylphenyl)-7-phenyl-benzo-[1,2-b:4,5-b']-difuran-2,6-di-one 在 perborate 作用下， 生成 3-(3-Methyl-4-nitrophenyl)-7-phenylfuro[2,3-f][1]benzofuran-2,6-dione
  参考文献：
  名称：

  Novel High Yielding Syntheses of Benzodifuranone Dyes Bearing Nitrogen Substituents at the 4-Position of a Pendent Phenyl Ring

  摘要：

  Otherwise inaccessible nitro benzodifuranone (BZDF) dyes are formed in good yield by treatment of 5-hydroxy-2-oxo-3-phenyl-2,3-dihydrobenzofuran either with 4NO(2)-3-R-C6H3CBrClCO2CH3 (R = H, alkyl, aryl or CO2CH3) in acetic acid. High yielding reduction of the nitro to the amino BZDF is accomplished by catalytic hydrogenation over Pd or by NaBH4/SnCl2.

  DOI：

  10.1080/00397919608003867

文献信息

• Novel High Yielding Syntheses of Benzodifuranone Dyes Bearing Nitrogen Substituents at the 4-Position of a Pendent Phenyl Ring
  作者：Stephen J. Bentley、David J. Milner

  DOI：10.1080/00397919608003867

  日期：1996.1

  Otherwise inaccessible nitro benzodifuranone (BZDF) dyes are formed in good yield by treatment of 5-hydroxy-2-oxo-3-phenyl-2,3-dihydrobenzofuran either with 4NO(2)-3-R-C6H3CBrClCO2CH3 (R = H, alkyl, aryl or CO2CH3) in acetic acid. High yielding reduction of the nitro to the amino BZDF is accomplished by catalytic hydrogenation over Pd or by NaBH4/SnCl2.