β-(trimethylgermyl)propionyl chloride | 112703-54-5

• 分子结构分类: 有机化合物 - 有机卤素化合物 - 酰卤
• 英文名称: β-(trimethylgermyl)propionyl chloride
• 英文别名: 3-trimethylgermylpropionyl chloride；3-(Trimethylgermyl)propanoyl chloride；3-trimethylgermylpropanoyl chloride
• CAS: 112703-54-5
• 化学式: C₆H₁₃ClGeO
• 分子量: 209.212
• InChiKey: HUZNSALZQJMBIA-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.48
• 重原子数：
  9
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.83
• 拓扑面积：
  17.1
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为反应物：
  描述：

  β-(trimethylgermyl)propionyl chloride 、 N,N,O-三(三甲基硅基)羟胺 在 乙醇 作用下， 以 乙醇 为溶剂， 以86%的产率得到β-trimethylgermyl-propiohydroxamic acid
  参考文献：
  名称：

  Kozyukov, Vik. P.; Feoktistov, A. E.; Mironov, V. F., Journal of general chemistry of the USSR, 1988, vol. 58, p. 937 - 939

  摘要：

  DOI：
• 作为产物：
  描述：

  3-(三氯锗)丙酰氯 、 甲基碘化镁 生成 β-(trimethylgermyl)propionyl chloride
  参考文献：
  名称：

  MIRONOV, V. F.;NURIDZHANYAN, A. K., METALLOORGAN. XIMIYA, 3,(1990) N, S. 1375-1379

  摘要：

  DOI：

文献信息

• Synthesis of azacrown ethers modified with side-chains containing germanium
  作者：Ryoko Suzuki、Takashi Matsumoto、Katsumi Tanaka、Yoshito Takeuchi、Tamotsu Taketomi

  DOI：10.1016/s0022-328x(01)01054-3

  日期：2001.11

  The reaction between ethanolamine (4) and tri- or tetraethylene tosylate (5) and (13) gave 9- and 12-membered monoazacrowns with a -CH2CH2OH residue on nitrogen, A-OH and B-OH, together with 18- and 24-membered diazacrown ethers with the same substituent on nitrogen, E-OH and F-OH. If 2-(2-aminoethoxy)ethanol (12) was used in the reaction described above, instead of 4, the final products, G-OH and H-OH, and K-OH and L-OH, have a longer side chain, -CH2CH2OCH2CH2OH, on nitrogen (Route 1). A series of reactions involving bromoethanol (6) and diethanolamine (9) formed, with 5 or 13, 18- and 24-membered monoazacrowns with the shorter substituent as described above, a 15-membered monoazacrown ether C-OH and an 18-membered D-OH. If 2-(2-chloroethoxy)ethanol (14) is used instead of 6, I-OH and J-OH are obtained (Route 2'). All these hydroxy azacrown ethers were made to react with 3-trimethylgermylpropionic acid (18) to give the corresponding germanium-containing A-L. A preliminary investigation was carried out on the cation transport capability of these germanium-containing azacrown ethers to observe whether germanium might enhance their cation transporting capability. (C) 2001 Published by Elsevier Science B.V.
• Gar, T. K.; Chernysheva, O. N.; Kisin, A. V., Journal of general chemistry of the USSR, 1987, vol. 57, p. 334 - 338
  作者：Gar, T. K.、Chernysheva, O. N.、Kisin, A. V.、Mironov, V. F.

  DOI：——

  日期：——
• MIRONOV, V. F.;NURIDZHANYAN, A. K., METALLOORGAN. XIMIYA, 3,(1990) N, S. 1375-1379
  作者：MIRONOV, V. F.、NURIDZHANYAN, A. K.

  DOI：——

  日期：——
• LUKEVITS, EH.;GERMANE, S. K.;TRUSHULE, M. A.;MIRONOV, V. F.;GAR, T. K.;VI+, XIM.-FARMATS. ZH., 21,(1987) N 9, 1070-1074
  作者：LUKEVITS, EH.、GERMANE, S. K.、TRUSHULE, M. A.、MIRONOV, V. F.、GAR, T. K.、VI+

  DOI：——

  日期：——
• KOZYUKOV, VIK. P.;FEOKTISTOV, A. E.;MIRONOV, V. F., ZH. OBSHCH. XIMII, 58,(1988) N 5, 1056-1060
  作者：KOZYUKOV, VIK. P.、FEOKTISTOV, A. E.、MIRONOV, V. F.

  DOI：——

  日期：——