Aethylenglycol-di-p-chlorbenzoat | 57847-59-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Aethylenglycol-di-p-chlorbenzoat
• 英文别名: Aethylenglykol-bis-<4-chlor-benzoat>；1,2-bis-(4-chloro-benzoyloxy)-ethane；1,2-Bis-(4-chlor-benzoyloxy)-aethan；2-(4-Chlorobenzoyl)oxyethyl 4-chlorobenzoate
• CAS: 57847-59-3
• 化学式: C₁₆H₁₂Cl₂O₄
• 分子量: 339.175
• InChiKey: PDUPYEJBFJWIJE-UHFFFAOYSA-N

物化性质

• 熔点：
  140 °C
• 沸点：
  454.8±30.0 °C(Predicted)
• 密度：
  1.356±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  5,6-Bis(4-chlorophenyl)-2,3-dihydro-1,4-dioxine 在 oxygen 、 polymer-bound Rose Bengal (SENSITOX I) 作用下， 以 二氯甲烷 、 丙酮 为溶剂， 生成 Aethylenglycol-di-p-chlorbenzoat
  参考文献：
  名称：

  1,2-二氧杂环丁烷分解的取代基效应：取代的1,6-二芳基-2,5,7,8-四氧杂双环[4.2.0]辛烷的Hammett相关性

  摘要：

  已经发现，通过将单重态氧加到取代的2,3-二芳基-1,4-二恶烯中而获得的1,2-二氧杂环丁烷的分解速率服从哈米特关系，ϱ + = -0.24（n = 15，r = 0.92 ）。结果被认为是支持双基机理的。

  DOI：

  10.1016/s0040-4039(00)87500-0

文献信息

• METHOD FOR MANUFACTURING CONJUGATED AROMATIC COMPOUND
  申请人：Oda Seiji

  公开号：US20110275859A1

  公开（公告）日：2011-11-10

  A method for manufacturing a conjugated aromatic compound comprising reacting an aromatic compound (A) wherein one or two leaving groups selected from the group consisting of an iodine atom, a bromine atom and a chlorine atom are bonded to an aromatic ring and the aromatic compound (A) does not have (c1) a group represented by the following formula (10): wherein A 1 represents a C1-C20 alkoxy group etc.; (g1) a C1-C20 alkyl group which may be substituted with a fluorine atom etc.; and (h1) a C2-C20 acyl group which may be substituted with a fluorine atom etc., at the neighboring carbon atom to the carbon atom to which the leaving group is bonded, with an aromatic compound (A) having the same structure as that of the above-mentioned aromatic compound (A) or an aromatic compound (B) wherein the aromatic compound (B) is structurally different from the above-mentioned aromatic compound (A), one or two leaving groups selected from the group consisting of an iodine atom, a bromine atom and a chlorine atom are bonded to an aromatic ring and the aromatic compound (B) does not have the above-mentioned (c1), (g1) and (h1) at the neighboring carbon atom to the carbon atom to which the leaving group is bonded, in the presence of (i) a nickel compound, (ii) a metal reducing agent, (iii) at least one ligand (L1) selected from the group consisting of a 2,2′-bipyridine compound having at least one electron-withdrawing group and having no substituent at 3-, 6-, 3′- and 6′-positions, and a 1,10-phenanthroline compound having at least one electron-withdrawing group and having no substituent at 2- and 9-positions, and (iv) at least one ligand (L2) selected from the group consisting of a 2,2′-bipyridine compound having at least one electron-releasing group and having no substituent at 3-, 6-, 3′- and 6′-positions, and a 1,10-phenanthroline compound having at least one electron-releasing group and having no substituent at 2- and 9-positions.

  一种制备共轭芳香化合物的方法，包括将含有一个或两个离去基团的芳香化合物（A）与含有相同结构的上述芳香化合物（A）或结构不同的芳香化合物（B）反应，其中这些离去基团选自碘原子、溴原子和氯原子，与芳香环结合，而芳香化合物（A）没有以下式（10）所代表的基团：其中A1代表C1-C20烷氧基等；（g1）代表C1-C20烷基基团，可能被氟原子等取代；以及（h1）代表C2-C20酰基基团，可能被氟原子等取代，与离去基团结合的碳原子的相邻碳原子处没有上述（c1）、（g1）和（h1），在（i）镍化合物、（ii）金属还原剂、（iii）从2,2′-联吡啶化合物和1,10-邻菲啰啉化合物中选择的至少一种配体（L1），具有至少一个吸电子基团且在3-、6-、3′-和6′-位置没有取代基，以及（iv）从2,2′-联吡啶化合物和1,10-邻菲啰啉化合物中选择的至少一种配体（L2），具有至少一个释电子基团且在3-、6-、3′-和6′-位置没有取代基团的情况下，在上述离去基团结合的碳原子的相邻碳原子处进行反应。
• Metal-free DDQ-mediated oxidative C–O coupling of acetalic sp³C–H bonds with carboxylic acids
  作者：Jiang-Sheng Li、Yuan Xue、Dong-Mei Fu、Dao-Lin Li、Zhi-Wei Li、Wei-Dong Liu、Huai-Lin Pang、Yue-Fei Zhang、Zhong Cao、Ling Zhang

  DOI：10.1039/c4ra08627a

  日期：——

  A simple and efficient DDQ-mediated oxidative C–O coupling reaction between acetalic sp3 C–H and carboxylic acid O–H bonds has been developed. This novel transformation smoothly proceeds without any metal catalyst and allows for the highly efficient synthesis of (un)symmetric glycol diesters in a single step.

  开发了一种简单高效的DDQ介导的氧化C–O偶联反应，涉及醛基sp3 C–H键和羧酸O–H键。此新型转化在无需任何金属催化剂的情况下顺利进行，并允许在一步中高效合成（非）对称的甘油二酯。
• Synthesis of glycol diesters through the depolymerization of polyethylene glycols with carboxylic acids using a proton-exchanged montmorillonite catalyst
  作者：Zen Maeno、Kaoru Midogochi、Takato Mitsudome、Tomoo Mizugaki、Koichiro Jitsukawa

  DOI：10.1016/j.tetlet.2018.01.056

  日期：2018.2

  convenient and sustainable method for the synthesis of glycol diesters was developed through the depolymerization of polyethylene glycols (PEGs) with carboxylic acids using proton-exchanged montmorillonite as an efficient solid acid catalyst. Several functionalized glycol diesters were obtained in good yields from PEGs and readily available carboxylic acids. Upon reaction completion, the catalyst could

  通过质子交换的蒙脱石作为有效的固体酸催化剂，通过聚乙二醇（PEG）与羧酸的解聚，开发了一种方便且可持续的乙二醇二酯合成方法。从PEG和容易获得的羧酸以良好的产率获得了几种官能化的二醇二酯。反应完成后，可以通过过滤容易地分离催化剂，并在其活性保持不变的情况下重复使用。
• Coupling of aryl and heteroaryl polyhalides
  申请人：AMOCO CORPORATION

  公开号：EP0025460A1

  公开（公告）日：1981-03-25

  Aryl and heteroaryl polyhalides are coupled in an aprotic solvent under an inert atmosphere by a catalyst mixture of a nickel compound and a ligand in the presence of a reducing metal.

  在惰性气氛下，芳基和杂芳基聚卤化物在非烷基溶剂中通过镍化合物和配体的催化剂混合物在还原金属存在下进行偶联。
• PREPARATION OF SOME GLYCOL BENZOATES
  作者：HAROLD C. HEIM、CHARLES F. POE

  DOI：10.1021/jo01186a001

  日期：1944.7