8,8,8-Trimethoxyoct-3-YN-1-OL | 88159-02-8

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 8,8,8-Trimethoxyoct-3-YN-1-OL
• 英文别名: 8,8,8-trimethoxyoct-3-yn-1-ol
• CAS: 88159-02-8
• 化学式: C₁₁H₂₀O₄
• 分子量: 216.277
• InChiKey: VINBJWNLOLVNDI-UHFFFAOYSA-N

物化性质

• 沸点：
  306.7±42.0 °C(Predicted)
• 密度：
  1.029±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.9
• 重原子数：
  15
• 可旋转键数：
  7
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.82
• 拓扑面积：
  47.9
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  8,8,8-Trimethoxyoct-3-YN-1-OL 生成 8-Methoxy-8-oxooct-3-ynoic acid
  参考文献：
  名称：

  A convenient strategy for the synthesis of β,γ-unsaturated aldehydes and acids. A construction of skipped dienes

  摘要：

  A novel strategy is described for the synthesis of beta,gamma-unsaturated aldehydes which are the useful synthons for the synthesis of arachidonic acid and other eicosanoid products. These beta,gamma-unsaturated aldehydes have been used in the total synthesis of arachidonic acid. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)01498-7
• 作为产物：
  描述：

  环氧乙烷 、 6,6,6-trimethoxy-1-hexyne 生成 8,8,8-Trimethoxyoct-3-YN-1-OL
  参考文献：
  名称：

  A convenient strategy for the synthesis of β,γ-unsaturated aldehydes and acids. A construction of skipped dienes

  摘要：

  A novel strategy is described for the synthesis of beta,gamma-unsaturated aldehydes which are the useful synthons for the synthesis of arachidonic acid and other eicosanoid products. These beta,gamma-unsaturated aldehydes have been used in the total synthesis of arachidonic acid. (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)01498-7