2,6-bis(2,5-dimethylphenyl)-4-phenylpyridine | 1333120-03-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2,6-bis(2,5-dimethylphenyl)-4-phenylpyridine
• CAS: 1333120-03-8
• 化学式: C₂₇H₂₅N
• 分子量: 363.502
• InChiKey: ZNAWEVQLKNXPKK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.3
• 重原子数：
  28
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.15
• 拓扑面积：
  12.9
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-(2,5-dimethylphenyl)ethanone oxime 在 sodium hydrogensulfite 、 copper(I) bromide 作用下， 以 二甲基亚砜 为溶剂， 反应 5.5h， 生成 2,6-bis(2,5-dimethylphenyl)-4-phenylpyridine
  参考文献：
  名称：

  铜催化肟肟与醛的偶联：吡啶合成的新策略

  摘要：

  乙酸肟肟与醛的铜催化偶联为合成高度取代的吡啶提供了新的策略。这种新颖的方法可耐受多种功能，并允许将肟肟乙酸酯快速精制为各种取代的吡啶。

  DOI：

  10.1021/ol202290y

文献信息

• Synthesis of symmetrical pyridines by iron-catalyzed cyclization of ketoxime acetates and aldehydes
  作者：YuKun Yi、Mi-Na Zhao、Zhi-Hui Ren、Yao-Yu Wang、Zheng-Hui Guan

  DOI：10.1039/c6gc03137d

  日期：——

  A novel and facile iron-catalyzed cyclization of ketoxime acetates and aldehydes for the green synthesis of substituted pyridines has been developed. In the presence of a FeCl3 catalyst, the reaction...

  已经开发出新颖且容易的铁催化的酮肟肟乙酸酯和醛的环化反应，以绿色合成取代的吡啶。在FeCl3催化剂的存在下，反应...
• Direct C–H Functionalization of Pyridine via a Transient Activator Strategy: Synthesis of 2,6-Diarylpyridines
  作者：Yang Zeng、Chunchun Zhang、Changzhen Yin、Maoshen Sun、Haiyan Fu、Xueli Zheng、Maolin Yuan、Ruixiang Li、Hua Chen

  DOI：10.1021/acs.orglett.7b00498

  日期：2017.4.21

  A Pd-catalyzed highly selective direct diarylation of pyridines has been developed using a transient activator strategy. Both (MeO)2SO2 and Cu2O are required for this transformation. The in situ generated N-methylpyridinium salt can be arylated at both 2- and 6-positions under the cooperative Pd/Cu catalysis. A subsequent N-demethylation then gives the 2,6-diarylpyridines. This protocol provides a

  已使用瞬态活化剂策略开发了Pd催化的吡啶的高选择性直接二芳基化反应。两者（MEO）2 SO 2和Cu 2需要用于该转化O操作。原位生成的N-甲基吡啶盐可以在Pd / Cu协同催化下在2-位和6-位芳基化。然后，随后的N-去甲基化得到2，6-二芳基吡啶。该协议为对称的2,6-二芳基吡啶提供了一种新颖的合成途径。
• Organic Compound, Charge-Transporting Material, and Organic Electroluminescent Element
  申请人：Yabe Masayoshi

  公开号：US20080145699A1

  公开（公告）日：2008-06-19

  There are provided an organic having both excellent hole transporting property and satisfactory electron transporting and showing excellent durability against electric oxidation/reduction and a high triplet excitation level, and a charge transporting material and an organic electroluminescent device each using the organic compound. The organic compound is represented by following Formula (I): wherein Cz 1 and Cz 2 each represent a carbazolyl group; Z represents a direct bond or an arbitrary linkage group enabling the conjugation of nitrogen atoms in the carbazole rings of Cz 1 and Cz 2 with each other; and Q represents a direct bond connecting to “G” in following Formula (II): wherein Ring B 1 represents a six-membered aromatic heterocyclic ring having “n” nitrogen atom(s) as hetero atom(s); “n” represents an integer of from 1 to 3; G represents a direct bond or an arbitrary linkage group connecting to Q when G connects to Q; Gs connect to carbon atoms at the ortho-position and the para-position with respect to nitrogen atom(s) in Ring B 1 ; G represents an aromatic hydrocarbon group when G does not connect to Q; and “m” represents an integer of from 3 to 5.

  提供了一种具有优异的空穴传输性能和令人满意的电子传输性能，并且表现出对电氧化/还原的优异耐久性和高三重激发水平的有机化合物，以及使用该有机化合物的电荷传输材料和有机电致发光器件。该有机化合物由以下式（I）表示：其中，Cz1和Cz2分别表示一个咔唑基团；Z表示直接键或任意连接基团，使Cz1和Cz2的咔唑环中的氮原子共轭连接在一起；Q表示连接到以下式（II）中的“G”的直接键：其中，环B1表示具有“n”个氮原子作为杂原子的六元芳香杂环；“n”表示从1到3的整数；G表示直接键或任意连接基团，当G连接到Q时；Gs连接到环B1中的氮原子的邻位和对位的碳原子上；当G未连接到Q时，G表示芳香烃基团；“m”表示从3到5的整数。
• ORGANIC COMPOUND, CHARGE-TRANSPORTING MATERIAL, AND ORGANIC ELECTROLUMINESCENT ELEMENT
  申请人：YABE Masayoshi

  公开号：US20090191426A2

  公开（公告）日：2009-07-30

  There are provided an organic having both excellent hole transporting property and satisfactory electron transporting and showing excellent durability against electric oxidation/reduction and a high triplet excitation level, and a charge transporting material and an organic electroluminescent device each using the organic compound. The organic compound is represented by following Formula (I): wherein Cz 1 and Cz 2 each represent a carbazolyl group; Z represents a direct bond or an arbitrary linkage group enabling the conjugation of nitrogen atoms in the carbazole rings of Cz 1 and Cz 2 with each other; and Q represents a direct bond connecting to “G” in following Formula (II): wherein Ring B 1 represents a six-membered aromatic heterocyclic ring having “n” nitrogen atom(s) as hetero atom(s); “n” represents an integer of from 1 to 3; G represents a direct bond or an arbitrary linkage group connecting to Q when G connects to Q; Gs connect to carbon atoms at the ortho-position and the para-position with respect to nitrogen atom(s) in Ring B 1 ; G represents an aromatic hydrocarbon group when G does not connect to Q; and “m” represents an integer of from 3 to 5.

  提供了一种具有优异的空穴输运性能和令人满意的电子输运性能，并显示出对电氧化/还原的优异耐久性和高三重激发能级的有机化合物，以及使用该有机化合物的电荷传输材料和有机电致发光器件。该有机化合物由以下式(I)表示：其中，Cz1和Cz2分别表示一个咔唑基团；Z表示直接键或任意连接基团，使Cz1和Cz2中的咔唑环中的氮原子共轭连接在一起；Q表示直接连接到以下式(II)中的“G”的直接键：其中，环B1表示一个具有“n”个氮原子的六元芳香杂环，n表示1至3的整数；G表示直接键或任意连接基团，当G连接到Q时；Gs连接到B1环中的氮原子的邻位和对位的碳原子；当G未连接到Q时，G表示芳香烃基团；m表示3至5的整数。
• US8324403B2
  申请人：——

  公开号：US8324403B2

  公开（公告）日：2012-12-04