2-n-butoxy-2'-nitrobiphenyl | 142505-57-5

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-n-butoxy-2'-nitrobiphenyl
• 英文别名: 1-(2-Butoxyphenyl)-2-nitrobenzene
• CAS: 142505-57-5
• 化学式: C₁₆H₁₇NO₃
• 分子量: 271.316
• InChiKey: FTJSPMFDUYDQCV-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.6
• 重原子数：
  20
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.25
• 拓扑面积：
  55
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-n-butoxy-2'-nitrobiphenyl 在 palladium on activated charcoal 一水合肼 作用下， 以 乙醇 为溶剂， 反应 6.0h， 以90%的产率得到2-amino-2'-n-butoxybiphenyl
  参考文献：
  名称：

  Cylisation reactions of 2-substituted biphenyl-2′-yldiazonium salts leading to O-alkyldibenzofuranium and S-alkyl-dibenzothiophenium salts: modified meerwein reagents

  摘要：

  The preparation of 2-amino-2'-methoxybiphenyl and 2-amino-2-thiomethoxybiphenyl and analogues and their transformation into diazonium salts and hence into dibenzofuranium and dibenzothiophenium salts is described together with their use as alkylating agents.

  DOI：

  10.1016/s0040-4020(01)88480-5
• 作为产物：
  描述：

  2-methoxy-2'-nitrobiphenyl 在 氢氧化钾 、 水 、 二溴三苯基膦 作用下， 反应 18.5h， 生成 2-n-butoxy-2'-nitrobiphenyl
  参考文献：
  名称：

  Cylisation reactions of 2-substituted biphenyl-2′-yldiazonium salts leading to O-alkyldibenzofuranium and S-alkyl-dibenzothiophenium salts: modified meerwein reagents

  摘要：

  The preparation of 2-amino-2'-methoxybiphenyl and 2-amino-2-thiomethoxybiphenyl and analogues and their transformation into diazonium salts and hence into dibenzofuranium and dibenzothiophenium salts is described together with their use as alkylating agents.

  DOI：

  10.1016/s0040-4020(01)88480-5

文献信息

• [EN] LIGHT MEDIATED REGULATION OF PROTEIN DIMERIZATION<br/>[FR] RÉGULATION MÉDIÉE PAR LA LUMIÈRE DE LA DIMÉRISATION DE PROTÉINE
  申请人：UNIV NORTH CAROLINA

  公开号：WO2012024558A2

  公开（公告）日：2012-02-23

  The present invention relates to photoactivatable rapamycin compounds. The invention further relates to the use of photoactivatable rapamycin compounds to regulate the dimerization and/or activity of polypeptides in a light dependent manner.
• Cylisation reactions of 2-substituted biphenyl-2′-yldiazonium salts leading to O-alkyldibenzofuranium and S-alkyl-dibenzothiophenium salts: modified meerwein reagents
  作者：Ian M. Downie、Harry Heaney(rk)、Graham Kemp、David King、Martin Wosley

  DOI：10.1016/s0040-4020(01)88480-5

  日期：1992.1

  The preparation of 2-amino-2'-methoxybiphenyl and 2-amino-2-thiomethoxybiphenyl and analogues and their transformation into diazonium salts and hence into dibenzofuranium and dibenzothiophenium salts is described together with their use as alkylating agents.