(2'-甲氧基乙烯)芘 | 93265-41-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 芘
• 中文名称: (2'-甲氧基乙烯)芘
• 英文名称: trans-1-(2-methoxyvinyl)pyrene
• 英文别名: (2'-Methoxyvinyl)pyrene；1-[(E)-2-methoxyethenyl]pyrene
• CAS: 93265-41-9
• 化学式: C₁₉H₁₄O
• 分子量: 258.32
• InChiKey: SGTJXHYDKUXJRK-VAWYXSNFSA-N

物化性质

• 沸点：
  453.4±14.0 °C(Predicted)
• 密度：
  1.234±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.4
• 重原子数：
  20
• 可旋转键数：
  2
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.05
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

安全信息

• 海关编码：
  2909309090

反应信息

• 作为反应物：
  描述：

  (2'-甲氧基乙烯)芘 在 正丁基锂 、 N,N,N'-三甲基乙二胺 作用下， 以 四氢呋喃 、 甲醇 、 正己烷 为溶剂， 反应 144.03h， 生成 cis-1-(2-methoxyvinyl)-2-methylpyrene
  参考文献：
  名称：

  Chemiluminescence mechanism and quantum yield of synthetic vinylpyrene analogs of benzo[a]pyrene-7,8-dihydrodiol

  摘要：

  DOI：

  10.1021/ja00275a040
• 作为产物：
  描述：

  1-芘甲醛 、 (methoxymethyl)triphenylphosphonium chloride 在 正丁基锂 作用下， 以 四氢呋喃 、 正己烷 为溶剂， 反应 15.0h， 生成 cis-1-(2-methoxyvinyl)pyrene 、 (2'-甲氧基乙烯)芘
  参考文献：
  名称：

  Chemiluminescence mechanism and quantum yield of synthetic vinylpyrene analogs of benzo[a]pyrene-7,8-dihydrodiol

  摘要：

  DOI：

  10.1021/ja00275a040

文献信息

• TETRAZINES/TRANS-CYCLOOCTENES IN SOLID PHASE SYNTHESIS OF LABELED PEPTIDES
  申请人：MEMORIAL SLOAN-KETTERING CANCER CENTER

  公开号：US20150359913A1

  公开（公告）日：2015-12-17

  This invention is in the field of labeled peptide construction for medical treatment and analysis. The invention relates to synthetic labeled peptide compositions, methods of synthesis, and methods of use for the synthetic labeled peptide compositions for medical treatment, imaging, and research purposes.

  这项发明涉及用于医疗治疗和分析的标记肽构建领域。该发明涉及合成标记肽组合物、合成方法以及用于医疗治疗、成像和研究目的的合成标记肽组合物的使用方法。
• REMOTE LASER INTERROGATION OF THREAT CLOUDS AND SURFACES
  申请人：Hartmann-Thompson Claire

  公开号：US20100019169A1

  公开（公告）日：2010-01-28

  This invention concerns the remote detection of threat clouds and evaluation of their components. Also included is the remote detection and evaluation of contamination on surfaces or in air streams. To enable this detection, fluorophores that are attached to POSS are used with two-photon LIF imaging that provides enhanced background-free imaging even in the presence of scattering particles such as dust, sand and water droplets.

  这项发明涉及远程检测威胁云并评估其成分。还包括远程检测和评估表面或空气流中的污染物。为了实现这种检测，使用附着在POSS上的荧光分子，并使用双光子LIF成像技术进行增强的无背景成像，即使存在散射颗粒，如灰尘、沙子和水滴。
• ANTI-TUMOR AGENT
  申请人：Toto Ltd.

  公开号：EP2298327A1

  公开（公告）日：2011-03-23

  Titanium oxide-antibody conjugated particles are disclosed, which are provided with selective binding ability without loss of dispersibility and catalytic activity by modifying titanium oxide conjugated particles, dispersed in a water-based solvent by a water-soluble polymer, with an antibody via a linker molecule bound without changing the nature of the water-soluble polymer. The present invention is an antitumor agent, comprising titanium oxide-antibody conjugated particles, wherein a linker molecule is bound to the titanium oxide surface of the titanium oxide conjugated particles, dispersed in a water-based solvent by a water-soluble polymer, via at least one functional group selected from a group consisting of a carboxyl group, an amino group, a diol group, a salicylic acid group, and a phosphoric acid group, and wherein the titanium oxide conjugated particles are further modified with an antibody via the linker molecule. This antitumor agent is concentrated in the affected area and can be utilized as an agent for diagnosis or for treatment in combination with ultrasonic irradiation.

  本发明公开了氧化钛-抗体共轭微粒，通过水溶性聚合物对分散在水基溶剂中的氧化钛共轭微粒进行改性，在不改变水溶性聚合物性质的情况下，通过连接分子与抗体结合，使其具有选择性结合能力，同时不损失分散性和催化活性。本发明是一种抗肿瘤剂，包括氧化钛-抗体共轭颗粒，其中连接分子通过水溶性聚合物与分散在水基溶剂中的氧化钛共轭颗粒的氧化钛表面结合、通过至少一个选自羧基、氨基、二元醇基、水杨酸基和磷酸基的官能团，氧化钛共轭微粒通过连接分子进一步用抗体修饰。这种抗肿瘤剂可集中在患处，可用作诊断剂或与超声波照射结合使用进行治疗。
• Heating mechanism for DNA amplification, extraction or sterilization using photo-thermal nanoparticles
  申请人：The Royal Institution for the Advancement of Learning/McGill University

  公开号：US10093971B2

  公开（公告）日：2018-10-09

  A heating mechanism for use in DNA applications such as DNA amplification, extraction and sterilization is provided. Nanoparticles having photo-thermal properties are put in contact with a reaction mixture and irradiated with an activation light beam to activate these photo-thermal properties, thereby releasing heat. Nanoparticles of several types may be used. Use of the same nanoparticles or of different one to monitor the reaction using a different light beam is also presented.

  本发明提供了一种用于 DNA 扩增、提取和灭菌等 DNA 应用的加热装置。将具有光热特性的纳米粒子与反应混合物接触，并用激活光束照射，以激活这些光热特性，从而释放热量。可以使用多种类型的纳米粒子。此外，还介绍了使用相同或不同的纳米粒子，用不同的光束监测反应的方法。
• Antimicrobial susceptibility testing and microbial identification
  申请人：SELUX DIAGNOSTICS, INC.

  公开号：US11339418B2

  公开（公告）日：2022-05-24

  Systems and methods for microbe identification (ID) in the context of phenotypic antimicrobial susceptibility testing (AST). Approaches for rapidly identifying polymicrobial samples are introduced that following perform one or more ID methods, such as matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI-TOF), PCR, or DNA hybridization, following sample incubation in two or more different media, including at least one selective media. Parallel ID and AST workflows are provided that may reduce the time from sample to AST result.

  表型抗菌药物敏感性检测（AST）中微生物鉴定（ID）的系统和方法。介绍了快速鉴定多微生物样本的方法，这些方法在样本在两种或两种以上不同培养基（包括至少一种选择性培养基）中培养后，执行一种或多种 ID 方法，如基质辅助激光解吸/电离飞行时间质谱（MALDI-TOF）、PCR 或 DNA 杂交。提供的并行 ID 和 AST 工作流程可缩短从样品到 AST 结果的时间。