4-Chlor-2,5-dimethyl-styrol | 1835-84-3

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4-Chlor-2,5-dimethyl-styrol
• 英文别名: 1-Chloro-4-ethenyl-2,5-dimethylbenzene
• CAS: 1835-84-3
• 化学式: C₁₀H₁₁Cl
• 分子量: 166.65
• InChiKey: RKNROQHNIFSVKX-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.1
• 重原子数：
  11
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.2
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为产物：
  描述：

  2-氯-1,4-二甲基苯 在 potassium hydrogensulfate 、 三氯化铝 、 aluminum isopropoxide 、 异丙醇 作用下， 生成 4-Chlor-2,5-dimethyl-styrol
  参考文献：
  名称：

  Dokukina; Koton, Zhurnal Obshchei Khimii, 1959, vol. 29, p. 2201; engl. Ausg. S. 2168

  摘要：

  DOI：

文献信息

• [EN] CHROMAN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION<br/>[FR] DÉRIVÉS DE CHROMAN-4-ONE POUR LE TRAITEMENT ET LA PROPHYLAXIE D'UNE INFECTION PAR LE VIRUS DE L'HÉPATITE B
  申请人：HOFFMANN LA ROCHE

  公开号：WO2020120642A1

  公开（公告）日：2020-06-18

  The present invention provides compounds having the general formula (I) wherein R1 to R10, Gi, G2, X and m are as described herein, compositions including the compounds and methods of using the compounds for treating hepatitis B.

  本发明提供具有一般式（I）的化合物，其中R1至R10、Gi、G2、X和m如本文所述，包括这些化合物的组合物以及使用这些化合物治疗乙型肝炎的方法。
• [EN] N-CONTAINING CHROMEN-4-ONE DERIVATIVES FOR THE TREATMENT AND PROPHYLAXIS OF HEPATITIS B VIRUS INFECTION<br/>[FR] DÉRIVÉS DE CHROMEN-4-ONE CONTENANT N POUR LE TRAITEMENT ET LA PROPHYLAXIE D'UNE INFECTION PAR LE VIRUS DE L'HÉPATITE B
  申请人：HOFFMANN LA ROCHE

  公开号：WO2020120528A1

  公开（公告）日：2020-06-18

  The present invention provides the compounds having the general formula: (I) wherein R1 to R8, and X are as described herein, compositions including the compounds and methods of using the compounds.

  本发明提供具有一般式：(I)的化合物，其中R1至R8和X如本文所述，包括这些化合物的组合物和使用这些化合物的方法。
• [EN] ALKYL PYRROLOPYRIMIDINE ANALOGS AND METHODS OF MAKING AND USING SAME<br/>[FR] ANALOGUES D'ALKYLE PYRROLOPYRIMIDINE ET LEURS PROCÉDÉS DE PRÉPARATION ET D'UTILISATION
  申请人：UNIV NORTH CAROLINA CHAPEL HILL

  公开号：WO2018094227A1

  公开（公告）日：2018-05-24

  The present disclosure is concerned with benzo annulene compounds that are capable of inhibiting a Mer tyrosine kinase and/or a Tyro3 tyrosine kinase and methods of treating a bacterial infection, a viral infection, and/or a disorder of uncontrolled cellular proliferation such as, for example, a cancer, using these compounds. This abstract is intended as a scanning tool for purposes of searching in the particular art and is not intended to be limiting of the present invention.

  本公开涉及能够抑制Mer酪氨酸激酶和/或Tyro3酪氨酸激酶的苯并环戊二烯化合物，以及使用这些化合物治疗细菌感染、病毒感染和/或细胞不受控制增殖的疾病，例如癌症的方法。本摘要旨在作为在特定领域搜索的扫描工具，并不意在限制本发明。
• Heat-resistant resin composition
  申请人：SHOWA DENKO KABUSHIKI KAISHA

  公开号：EP0348906A1

  公开（公告）日：1990-01-03

  A resin composition comprising (A) at least one heat-resistant resin, (B) at least one thermoplastic resin, (C) an antimony oxide, (D) at least one bromine-­containing reaction product selected from the group consisting of (1) a compound having a molecular weight of from 1,200 to 6,000 and a bromine content of from 5.0 to 60% by weight which is obtained by reacting a bromine-containing epoxy compound and 1,3,5-­tribromophenol, and (2) a compound obtained by reacting a bromine-containing epoxy compound having an epoxy equivalent of from 450 to 7,000 and a bromine content of from 5.0 to 52% by weight and an acrylonitrile-butadiene copolymer having a carboxyl group at the both terminals thereof and a molecular weight of from 1,000 to 10,000, and (E) at least one silicon-containing compound selected from the group consisting of (1) silicone oil, (2) a ladder silicone resin, and (3) an alkoxysilane having a mercapto group, a vinyl group or a methacryloyl group, is disclosed. The resin composition is excellent in heat resistance, impact resistance, flame retardancy, and molding properties.

  一种树脂组合物，包括(A) 至少一种耐热树脂，(B) 至少一种热塑性树脂，(C) 氧化锑，(D) 至少一种含溴反应产物，该反应产物选自以下组别：(1) 一种化合物，其分子量为 1,200 至 6,000 之间，溴含量为 5.0至60%(重量)的化合物，它是由含溴环氧化合物和1,3,5-三溴苯酚反应得到的；和(2)由含溴环氧化合物和含溴环氧化合物反应得到的化合物，含溴环氧化合物的环氧当量为450至7,000，溴含量为5.(E) 至少一种含硅化合物，选自(1)硅油，(2)阶梯硅树脂和(3)具有巯基、乙烯基或甲基丙烯酰基的烷氧基硅烷组成的组。该树脂组合物具有优异的耐热性、抗冲击性、阻燃性和成型性能。
• PARASITICIDAL COMPOSITIONS COMPRISING INDOLE DERIVATIVES, METHODS AND USES THEREOF
  申请人：Boehringer Ingelheim Animal Health USA Inc.

  公开号：EP3517524B1

  公开（公告）日：2021-05-26