Methyl perfluoro(N-morpholino acetate) | 132917-44-3

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Methyl perfluoro(N-morpholino acetate)
• 英文别名: Methyl 2,2-difluoro-2-(2,2,3,3,5,5,6,6-octafluoromorpholin-4-yl)acetate
• CAS: 132917-44-3
• 化学式: C₇H₃F₁₀NO₃
• 分子量: 339.09
• InChiKey: HPRJVNZCSUQROO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.6
• 重原子数：
  21
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.86
• 拓扑面积：
  38.8
• 氢给体数：
  0
• 氢受体数：
  14

反应信息

• 作为产物：
  描述：

  甲醇 、 Perfluoro(morpholinoacetyl) fluoride 生成 Methyl perfluoro(N-morpholino acetate)
  参考文献：
  名称：

  含氮羧酸的电化学氟化。环状氨基取代羧酸甲酯的氟化

  摘要：

  对与甘氨酸，丙氨酸或β-丙氨酸有关的环状氨基取代的羧酸的九种甲酯进行电化学氟化。这样以合理的产率得到了相应的全氟氟化物和裂解产物。作为环状氨基取代基，研究了吡咯烷基，吗啉代，哌啶子基，六亚甲基亚氨基和N'-甲基哌嗪基。未观察到环化副产物的形成，这与脂族二烷基氨基取代的羧酸的氟化形成对比。从这样的2-环氨基丙酸甲酯[环氨基：吡咯烷基，吗啉代或哌啶子基]，与全氟酸氟化物一起得到全氟甲基酯，产率为1-2％和14-29。 ％ 分别。前一种化合物的形成归因于庞大的环状氨基的阻断作用。报告了所获得的新化合物的物理性质及其光谱（19 F NMR，质量和IR）数据。

  DOI：

  10.1016/s0022-1139(00)80494-7

文献信息

• METHODS OF USING HYDROFLUOROETHERS AS HEAT TRANSFER FLUIDS
  申请人：FLYNN Richard M.

  公开号：US20110100601A1

  公开（公告）日：2011-05-05

  An apparatus is provided that includes a device and a mechanism for heat transfer. The mechanism includes a hydrofluoroether heat-transfer fluid wherein the heat transfer fluid is represented by the following structure: Y—R f —CH 2 OCH 2 R f —Y wherein R f may be the same or different and is, independently, selected from the group consisting of perfluorinated alkylene groups which may be linear, cyclic, or branched having from 1 to 10 carbon atoms, partially fluorinated alkylene groups having from 1 to 10 carbon atoms, and derivatives thereof wherein one or more carbon atoms are replaced by catenated nitrogen or oxygen heteroatoms, wherein each R f contains at most one hydrogen atom, wherein Y represents H, F, or an R f CH 2 OCH 2 — group, and wherein the total number of carbon atoms in the molecule is at least 6. A method of transferring heat including the device and the provided heat-transfer fluid is also provided

  提供了一种装置，包括设备和用于传热的机制。该机制包括一种氢氟醚传热流体，其中所述传热流体由以下结构表示：Y—Rf—CH2OCH2Rf—Y，其中Rf可以相同或不同，独立地从以下组中选择：具有1至10个碳原子的全氟烷基，可以是线性、环状或支链的，具有1至10个碳原子的部分氟化烷基和其衍生物，其中一个或多个碳原子被串联的氮或氧杂原子所取代，其中每个Rf分子中最多含有一个氢原子，其中Y表示H、F或RfCH2OCH2-基团，分子中的总碳原子数至少为6。还提供了一种包括所述装置和提供的传热流体的传热方法。
• US8261560B2
  申请人：——

  公开号：US8261560B2

  公开（公告）日：2012-09-11
• [EN] METHODS OF USING HYDROFLUOROETHERS AS HEAT TRANSFER FLUIDS<br/>[FR] PROCÉDÉS D'UTILISATION D'HYDROFLUOROÉTHERS COMME FLUIDES CALOPORTEURS
  申请人：3M INNOVATIVE PROPERTIES CO

  公开号：WO2011053628A2

  公开（公告）日：2011-05-05

  An apparatus is provided that includes a device and a mechanism for heat transfer. The mechanism includes a hydrofluoroether heat-transfer fluid wherein the heat transfer fluid is represented by the following structure: Y-Rf-CH2OCH2Rf-Y wherein Rf may be the same or different and is, independently, selected from the group consisting of perfluorinated alkylene groups which may be linear, cyclic, or branched having from 1 to 10 carbon atoms, partially fluorinated alkylene groups having from 1 to 10 carbon atoms, and derivatives thereof wherein one or more carbon atoms are replaced by catenated nitrogen or oxygen heteroatoms, wherein each Rf contains at most one hydrogen atom, wherein Y represents H, F, or an RfCH2OCH2- group, and wherein the total number of carbon atoms in the molecule is at least 6. A method of transferring heat including the device and the provided heat-transfer fluid is also provided.
• The electrochemical fluorination of nitrogen-containing carboxylic acids. Fluorination of methyl esters of cyclic amino-group substituted carboxylic acids
  作者：Takashi Abe、Eiji Hayashi、Haruhiko Fukaya、Hajime Baba

  DOI：10.1016/s0022-1139(00)80494-7

  日期：1990.11

  Nine methyl esters of cyclic amino-group substituted carboxylic acids related to glycine, alanine or β-alanine were subjected to electrochemical fluorination. This afforded the corresponding perfluoroacid fluorides together with cleavage products in fair yields. As cyclic amino-substituents, pyrrolidino-, morpholino-, piperidino-, hexamethyleneimino- and N′-methyl-piperazinyl-groups were investigated

  对与甘氨酸，丙氨酸或β-丙氨酸有关的环状氨基取代的羧酸的九种甲酯进行电化学氟化。这样以合理的产率得到了相应的全氟氟化物和裂解产物。作为环状氨基取代基，研究了吡咯烷基，吗啉代，哌啶子基，六亚甲基亚氨基和N'-甲基哌嗪基。未观察到环化副产物的形成，这与脂族二烷基氨基取代的羧酸的氟化形成对比。从这样的2-环氨基丙酸甲酯[环氨基：吡咯烷基，吗啉代或哌啶子基]，与全氟酸氟化物一起得到全氟甲基酯，产率为1-2％和14-29。 ％ 分别。前一种化合物的形成归因于庞大的环状氨基的阻断作用。报告了所获得的新化合物的物理性质及其光谱（19 F NMR，质量和IR）数据。