2R,S-propionoxydecanoic acid

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2R,S-propionoxydecanoic acid
• 英文别名: 2-Propanoyloxydecanoic acid；2-propanoyloxydecanoic acid
• 化学式: C₁₃H₂₄O₄
• 分子量: 244.331
• InChiKey: BDZQHGRSLVREIM-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.2
• 重原子数：
  17
• 可旋转键数：
  11
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  trans-10-hydroperoxyoctadec-8-enoic acid 在 吡啶 、 sodium tetrahydroborate 作用下， 反应 18.0h， 生成 2R,S-propionoxydecanoic acid
  参考文献：
  名称：

  A gas-liquid chromatographic method for steric analysis of 2-hydroxy, 3-hydroxy, and 2,3-dihydroxy acids

  摘要：

  A method was developed for assignment of the absolute configuration of oxylipin-derived 2-hydroxy acids, 3-hydroxy acids and 2,3-dihydroxy acids. The monohydroxy acids were converted into diastereomeric N-(propionoxyacyl)-L-phenylalanine-methyl ester (PAP) derivatives by coupling to the methyl ester of L-phenylalanine followed by propionylation, whereas the 2,3-dihydroxy acids were derivatized by treatment with L-phenylalanine methyl ester followed by acetone and perchloric acid, to afford diastereomeric N-(2,3-isopropylidenedioxyacyl)-L-phenyl methyl ester (IAP) derivatives. The PAP and IAP derivatives were readily resolved by capillary gas-liquid chromatography. In addition, the method described allowed steric analysis of 3-hydroxy-3-methylheptanoic acid, a branched chain hydroxy acid derived from the prostaglandin analogue, misoprostol.

  DOI：

  10.1016/0009-3084(94)90056-6

文献信息

• ESTERS FOR USE AS A BASE STOCK AND IN LUBRICANT APPLICATIONS
  申请人：Narine Suresh

  公开号：US20120208732A1

  公开（公告）日：2012-08-16

  This invention relates to base ester compounds and complex ester compounds that can be used as a base stock for lubricant applications or a base stock blend component for use in a finished lubricant or for particular applications, and methods of making the same. The base ester compounds and complex esters described herein comprise dimer and/or trimer esters, and their respective branched derivatives.

  本发明涉及基础酯化合物和复杂酯化合物，可用作润滑剂应用的基础油或用于成品润滑剂或特定应用的基础油混合组分，以及其制备方法。这里描述的基础酯化合物和复杂酯化合物包括二聚体和/或三聚体酯化物及其相应的支链衍生物。
• US8741822B2
  申请人：——

  公开号：US8741822B2

  公开（公告）日：2014-06-03
• US9359571B2
  申请人：——

  公开号：US9359571B2

  公开（公告）日：2016-06-07
• A gas-liquid chromatographic method for steric analysis of 2-hydroxy, 3-hydroxy, and 2,3-dihydroxy acids
  作者：Lian-Ying Zhang、Mats Hamberg

  DOI：10.1016/0009-3084(94)90056-6

  日期：1994.12

  A method was developed for assignment of the absolute configuration of oxylipin-derived 2-hydroxy acids, 3-hydroxy acids and 2,3-dihydroxy acids. The monohydroxy acids were converted into diastereomeric N-(propionoxyacyl)-L-phenylalanine-methyl ester (PAP) derivatives by coupling to the methyl ester of L-phenylalanine followed by propionylation, whereas the 2,3-dihydroxy acids were derivatized by treatment with L-phenylalanine methyl ester followed by acetone and perchloric acid, to afford diastereomeric N-(2,3-isopropylidenedioxyacyl)-L-phenyl methyl ester (IAP) derivatives. The PAP and IAP derivatives were readily resolved by capillary gas-liquid chromatography. In addition, the method described allowed steric analysis of 3-hydroxy-3-methylheptanoic acid, a branched chain hydroxy acid derived from the prostaglandin analogue, misoprostol.