N-(2-(4-methoxyphenyltelluro)ethyl)morpholine | 325775-21-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯酚醚
• 英文名称: N-(2-(4-methoxyphenyltelluro)ethyl)morpholine
• 英文别名: N-(2-(p-methoxyphenyltelluro)ethyl)morpholine；N-{2(4-methoxyphenyltelluro)ethyl}morpholine；N-[2-(4-methoxyphenyltelluro)ethyl]morpholine；N-[2-(MeO-phenyltelluro)ethyl]morpholine；N-{2-(4-methoxyphenyl-telluro)-ethyl}morpholine；4-[2-(4-methoxyphenyl)tellanylethyl]morpholine
• CAS: 325775-21-1
• 化学式: C₁₃H₁₉NO₂Te
• 分子量: 348.899
• InChiKey: XSMOBQPINXJIPI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.78
• 重原子数：
  17
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.54
• 拓扑面积：
  21.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  二氯(p-甲基异丙苯)钌(II) 二聚体 、 N-(2-(4-methoxyphenyltelluro)ethyl)morpholine 以 二氯甲烷 为溶剂， 以65%的产率得到
  参考文献：
  名称：

  N-{2-(4-methoxyphenyltelluro)ethyl}morpholine (L1) and its platinum(II) and ruthenium(II) complexes. Synthesis and crystal structure of L1 and trans-[PtCl2(L1)2]

  摘要：

  The first tellurated derivative of morpholine, N-{2-(4-methoxyphenyltelluro)ethyl}morpholine (L-1) has been synthesized by reacting in situ generated ArTe- with 4-(2-chloroethyl)morpholine hydrochloride under N-2 atmosphere. The compound L-1 gives molecular ion peak at m/z 351 and is characterized structurally. The donor atoms N and Te in compound L-1 are rightly oriented for its ligation in bidentate mode. The Te-C(alkyl) is 0.02 Angstrom longer than Te-C(aryl). The complexes of ligand L-1 having composition [PtCl2(L-1)(2)] (1) and [RuCl2(p-cymene)L-1] (2) have been synthesized. The compound 1 has been characterized structurally. The Pt has a square planar geometry in complex 1 and two molecules of ligand L-1 bonded through Te alone are trans to each other (Pt-Te = 2.583(2) Angstrom). The C-13{H-1} NMR spectrum of complex 1 is as expected. The H-1 NMR spectrum of single crystals of complex 1 shows multiplication of signals, which is supported by HETCOR experiments. The complex 2 also has ligand L-1 in a monodentate coordination mode, bonded through Te alone. This is supported by deshielded CH2Te and ArC-Te signals in H-1 and C-13{H-1} NMR spectra of complex 2 with respect to those of free ligand L-1. The HETCOR spectrum of complex 2 has been used to authenticate the assignments of CH2Te group, as its two protons appear to be magnetically non-equivalent. (C) 2001 Elsevier Science B.V. All rights reserved.

  DOI：

  10.1016/s0020-1693(00)00355-8
• 作为产物：
  描述：

  bis(4-methoxyphenyl)ditelluride 在 sodium tetrahydroborate 、 sodium hydroxide 作用下， 以 乙醇 为溶剂， 生成 N-(2-(4-methoxyphenyltelluro)ethyl)morpholine
  参考文献：
  名称：

  Palladiumd(II) complexes of N-{2-(aryltelluro)ethyl}morpholine/piperidine: Synthesis, structure, application in Heck coupling and unprecedented conversion into nano-sized PdTe

  摘要：

  The complexes, [PdCl2(L)] (1-2) (L = N-{2-(aryltelluro)ethyl}morpholine/piperidine) have been synthesized and characterized by multi-nuclei NMR and single crystal X-ray crystallography. They on reaction with aryl chloride/bromide and morpholine/piperidine give similar to 5 nm size nano-particles of PdTe. The 0.005 mol% of 2 is suitable for Heck coupling (conversion up to 93%). (C) 2011 Elsevier B.V. All rights reserved.

  DOI：

  10.1016/j.inoche.2011.10.015

文献信息

• “Piano‐Stool” Complexes of Ruthenium(II) Designed with Arenes and <i>N</i> ‐[2‐(Arylchalcogeno)ethyl]morpholines: Highly Active Catalysts for the Oxidation of Alcohols with <i>N</i> ‐Methylmorpholine <i>N</i> ‐Oxide, <i>tert</i> ‐Butyl Hydroperoxide and Sodium Periodate and Oxychloride
  作者：Pradhumn Singh、Ajai K. Singh

  DOI：10.1002/ejic.201000319

  日期：2010.9

  irreversible oxidation (E ½ = 0.290-0.586 V). All the ruthenium complexes have been explored for their catalytic activity in the oxidation of primary and secondary alcohols with N-methylmorpholine N-oxide (NMO), tBuOOH, NaOCl, and NaI0 4 (TON values upto 9.8 × 10 4 ). The efficiency of the catalytic oxidation reaction decreases in the order Te > Se > S. The intermediate species involved in the oxidation reactions

  [(η 6 -C 6 H 6 )RuCl(μ-Cl)} 2 ]和[(η 6 -p-cymene)-RuCl(μ-Cl)} 2 ]与N-[2-的反应(芳基硫属元素)乙基]吗啉(L)（芳基=Ph/2-吡啶基，S，Ph，Te，4-MeOC 6 H 4）和NH 4 PF 6 导致Ru II的“钢琴-粪便”复合物组成 [RuCl(η 6 -C 6 H 6 )(L)][PF 6 ]/[RuCl(η 6 -p-伞花烃)(L)]-[PF 6 ]，给出特征 1 H, 13 C 1 H}、77 Se 1 H} 和 125 Te 1 H} NMR 光谱。其中一些还通过 X 射线晶体学表征 [Ru-S、Ru-Se 和 Ru-Te 键长：2.3815(12)/2.3742(14)、2.4837(14) 和 2.6143(7) A，分别]。循环伏安图显示所有配合物都发生不可逆氧化 (E ½ = 0.290-0
• Rhodium(III) complexes of N-{2-(arylseleno/telluro)ethyl} morpholine: Synthesis, structure and applications as efficient catalyst for transfer hydrogenation reaction of ketones
  作者：Pradhumn Singh、Dipanwita Das、Monika Singh、Ajai K. Singh

  DOI：10.1016/j.inoche.2010.05.014

  日期：2010.8

  resulting in complexes [RhCl2(L1/L2)4][ClO4] (1/2). 1H, 13C1H} and 77Se1H}/125Te1H} NMR spectra of L1, L2, 1 and 2 were found characteristic. The single crystal structure of 2 has been solved. The L2 binds with Rh in 2 as a monodentate ligand. The geometry around Rh is distorted octahedral. The Rh–Te distances are in the range 2.6509(9)–2.6688(8) Ǻ. Both the complexes efficiently catalyze transfer hydrogenation

  摘要 通过 PhSe−/ArTe−（原位生成）与（2-氯乙基）吗啉盐酸盐反应合成的 N-2-(Arylseleno/telluro)ethyl}morpholine (L1/L2)，与 RhCl3·3H2O 反应生成复合物 [RhCL2 (L1/L2)4][ClO4] (1/2)。发现 L1、L2、1 和 2 的 1H、13C1H} 和 77Se1H}/125Te1H} NMR 谱具有特征性。2的单晶结构已经解决。L2 作为单齿配体与 2 中的 Rh 结合。Rh 周围的几何形状是扭曲的八面体。Rh–Te 距离在 2.6509(9)–2.6688(8) Ǻ范围内。这两种配合物都能有效催化苯乙酮（TON/TOF 高达 9.9 × 104/9.9 × 103 h- 1）和二苯甲酮（TON 高达 9.8 × 104 和 TOF 高达 9.8 × 103 h- 1）的转移氢化反应。
• N-?2-(4-Methoxyphenyltelluro)ethyl?morpholine (L1) and bis?2-(N-morpholino)ethyl?telluride (L2): synthesis and complexation with palladium(II) and mercury(II). Crystal structures of trans-[PdCl2(L1)2] and trans-[PdCl2(L2)2]
  作者：A Singh

  DOI：10.1016/s0022-328x(00)00382-x

  日期：2000.10.20

  resulted in N-2-(4-methoxyphenyltelluro)ethyl}morpholine (L1) and bis2-(N-morpholino)ethyl}telluride (L2), respectively, which are first tellurated derivatives of morpholine. 1H- and 13C1H}-NMR spectra of L1 are as expected but HETCOR experiments are used to assign the overlapping signals of CH2Te and CH2N in 1H-NMR spectrum of L2. The complexes of stoichiometries [PdCl2(L1/L2)2] (1/3) and [HgBr2(L1/L2)]2

  的反应中的4-（2-氯乙基）吗啉盐酸盐与ARTE -和Te 2-，原位产生（在N 2气氛中）已经导致ñ - 2-（4- methoxyphenyltelluro）乙基}吗啉（大号1）和双2-（N-吗啉代）乙基}碲化物（L 2），它们是吗啉的第一碲代衍生物。1 H-和13 C 1 1个1 H} -NMR谱大号1是如预期但HETCOR实验用于分配CH的重叠信号2 Te和CH 2 N合1L 2的1 H-NMR谱。化学计量的复合物[的PdCl 2（大号1 /大号2）2 ]（1 / 3）和[HgBr 2（大号1 /大号2）] 2（2 / 4）进行合成。四个络合物的NMR（1 H和13 C 1 H}）光谱均具有相对于游离L 1 / L 2而言被屏蔽的CH 2 Te和ArCTe信号，表明两个配体仅通过Te配位。的反式的Pd络合物1和3在结构上，其特征在于及其PdTe键长（平均值）分别为2.596和2