dimethyl 3,3'-(pyridine-2,6-diyl)dibenzoate | 1258419-84-9

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: dimethyl 3,3'-(pyridine-2,6-diyl)dibenzoate
• CAS: 1258419-84-9
• 化学式: C₂₁H₁₇NO₄
• 分子量: 347.37
• InChiKey: QMGPQHHWHAINRO-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.99
• 重原子数：
  26.0
• 可旋转键数：
  4.0
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.1
• 拓扑面积：
  65.49
• 氢给体数：
  0.0
• 氢受体数：
  5.0

反应信息

• 作为反应物：
  描述：

  dimethyl 3,3'-(pyridine-2,6-diyl)dibenzoate 在 sodium hydroxide 作用下， 以 水 为溶剂， 生成 2,6-二(3-羧基苯基)吡啶
  参考文献：
  名称：

  低核灯笼型多孔配位笼的合成与表征。

  摘要：

  灯笼型M 4 L 4桨式保持器中的永久孔隙率很少，只有基于萘，萘啶和二乙炔基苯的连接剂才有报道。这项工作提出了小灯笼的设计，合成和表征，这些灯笼表现出超过200 m 2 g -1的CO 2可及BET表面积。这些笼的晶体堆积和孔隙率可通过配体官能化或合成中使用的M 2+来源的选择来调整。由于它们的核数低，这些内部M–M距离小于5Å的笼子代表了永久性微孔协调笼子的尺寸下限。

  DOI：

  10.1039/d0cc03266b
• 作为产物：
  描述：

  2,6-二溴吡啶 、 3-甲氧基羰基苯硼酸 在 (1,1'-bis(diphenylphosphino)ferrocene)palladium(II) dichloride 、 potassium carbonate 作用下， 以 四氢呋喃 、 水 为溶剂， 生成 dimethyl 3,3'-(pyridine-2,6-diyl)dibenzoate
  参考文献：
  名称：

  低核灯笼型多孔配位笼的合成与表征。

  摘要：

  灯笼型M 4 L 4桨式保持器中的永久孔隙率很少，只有基于萘，萘啶和二乙炔基苯的连接剂才有报道。这项工作提出了小灯笼的设计，合成和表征，这些灯笼表现出超过200 m 2 g -1的CO 2可及BET表面积。这些笼的晶体堆积和孔隙率可通过配体官能化或合成中使用的M 2+来源的选择来调整。由于它们的核数低，这些内部M–M距离小于5Å的笼子代表了永久性微孔协调笼子的尺寸下限。

  DOI：

  10.1039/d0cc03266b

文献信息

• Selective palladium-catalysed arylation of 2,6-dibromopyridine using N-heterocyclic carbene ligands
  作者：D. Prajapati、C. Schulzke、M. K. Kindermann、A. R. Kapdi

  DOI：10.1039/c5ra10561g

  日期：——

  A selective palladium-catalysed arylation of 2,6-dibromopyridine has been developed by employing N-heterocyclic carbene ligands. Selective mono-arylation was performed in water/acetonitrile solvent system at ambient temperature with catalyst loading of 0.1 mol%. This reaction was also found to proceed smoothly in water although at a slightly elevated temperature of 80 °C. 2,6-Disubstituted and diversely

  通过使用N-杂环卡宾配体已经开发了钯的2,6-二溴吡啶的选择性芳基化。选择性单芳基化反应是在水/乙腈溶剂体系中于室温下以0.1 mol％的催化剂负载量进行的。尽管在稍高的80℃温度下，也发现该反应在水中能顺利进行。还以高收率获得了2，6-二取代的和被不同取代的2，6-吡啶，这对于有机和药物化学家将是重要的。
• Ligand Bridging-Angle-Driven Assembly of Molecular Architectures Based on Quadruply Bonded Mo−Mo Dimers
  作者：Jian-Rong Li、Andrey A. Yakovenko、Weigang Lu、Daren J. Timmons、Wenjuan Zhuang、Daqiang Yuan、Hong-Cai Zhou

  DOI：10.1021/ja1080794

  日期：2010.12.15

  A systematic exploration of the assembly of Mo-2(O2C-)(4)-based metal-organic molecular architectures structurally controlled by the bridging angles of rigid organic linkers has been performed. Twelve bridging dicarboxylate ligands were designed to be of different sizes with bridging angles of 0, 60, 90, and 120 degrees while incorporating a variety of nonbridging functional groups, and these ligands were used as linkers. These dicarboxylate linkers assemble with quadruply bonded Mo-Mo clusters acting as nodes to give 13 molecular architectures, termed metal-organic polygons/polyhedra with metal cluster node arrangements of a linear shape, triangle, octahedron, and cuboctahedron/anti-cuboctahedron. The syntheses of these complexes have been optimized and their structures determined by single-crystal X-ray diffraction. The results have shown that the shape and size of the resulting molecular architecture can be controlled by tuning the bridging angle and size of the linker, respectively. Functionalization of the linker can adjust the solubility of the ensuing molecular assembly but has little or no effect on the geometry of the product. Preliminary gas adsorption, spectroscopic, and electrochemical properties of selected members were also studied. The present work is trying to enrich metal-containing supramolecular chemistry through the inclusion of well-characterized quadruply bonded Mo-Mo units into the structures, which can widen the prospect of additional electronic functionality, thereby leading to novel properties.