4,4'-diacetoxy-3,5,3',5'-tetrabromo-biphenyl | 574706-24-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 4,4'-diacetoxy-3,5,3',5'-tetrabromo-biphenyl
• 英文别名: 4,4'-Diacetoxy-3,5,3',5'-tetrabrom-biphenyl；[4-(4-Acetyloxy-3,5-dibromophenyl)-2,6-dibromophenyl] acetate
• CAS: 574706-24-4
• 化学式: C₁₆H₁₀Br₄O₄
• 分子量: 585.869
• InChiKey: OAZIBIRGMRSGRJ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.8
• 重原子数：
  24
• 可旋转键数：
  5
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  52.6
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  4,4'-diacetoxy-3,5,3',5'-tetrabromo-biphenyl 、 溶剂黄146 、 alkaline earth salt of/the/ methylsulfuric acid 生成 3,5-二溴-4-羟基苯甲酸
  参考文献：
  名称：

  Moir, Chemisches Zentralblatt, 1913, vol. 84, # II, p. 1665

  摘要：

  DOI：
• 作为产物：
  描述：

  2-[双(3,5-二溴-4-羟基苯基)甲基]苯甲酸 在 硫酸 作用下， 生成 4,4'-diacetoxy-3,5,3',5'-tetrabromo-biphenyl
  参考文献：
  名称：

  Moir, Chemisches Zentralblatt, 1913, vol. 84, # II, p. 1665

  摘要：

  DOI：

文献信息

• Magnesium-Flush Infusion into the Aortic Root Just before Reperfusion Reduces the Requirement for Internal Defibrillation and Early Post-Perfusion Arrhythmias
  作者：Y Beşoğul、B Tünerir、C Özdemir、R Aslan

  DOI：10.1177/147323000303100306

  日期：2003.6

  Pre- and post-operative administration of magnesium has beneficial effects on post-operative ischaemia and reperfusion arrhythmias, but few studies have examined whether intra-operatively administered magnesium can prevent the effects of intra-operative arrhythmias. The aim of this randomized, double-blind study was to compare the effects of intra-operative magnesium or placebo on intra-operative arrhythmias in patients undergoing coronary bypass grafting. Patients received a flush infusion of magnesium or placebo into the aortic root before cross-clamp removal. The results showed that rate of spontaneous resumption of a cardiac rhythm was significantly higher, and number of shocks for defibrillation, energy requirement for defibrillation and rate of intra-operative ventricular tachyarrhythmias were significantly lower in the magnesium group, compared with the placebo group. The differences in need for temporary pacing, and in serum magnesium levels, were not significant. Intra-operative administration of magnesium has beneficial effects on the outcome of surgery. Larger, multicentre clinical investigations should now be undertaken.

  术前和术后给予镁剂对术后缺血再灌注心律失常有益，但很少有研究探讨术中给予镁剂是否可以预防术中心律失常的影响。这项随机、双盲研究的目的是比较术中给予镁剂或安慰剂对冠脉搭桥术患者术中心律失常的影响。患者在去除主动脉夹闭前接受了镁剂或安慰剂的冲洗输注。结果显示，心脏节律自发恢复的速率显著更高，除颤次数、除颤能量需求和术中心室心动过速发生率在镁剂组明显低于安慰剂组。临时起搏的需求和血清镁水平的差异不显著。术中给予镁剂对手术结果有益。现在应进行更大规模、多中心的临床调查。
• A phosphine sulfide, a manufacturing process therefor and a use thereof
  申请人：MITSUI CHEMICALS, INC.

  公开号：EP0972776A1

  公开（公告）日：2000-01-19

  A basic organic compound which is soluble in an organic solvent, does not have problems in its preparation or handling and exhibits catalytic activity as a basic compound, is a phosphine sulfide represented by the (1): The phosphine sulfide represented by formula (1), is made by reacting one molecule of thiophosphoryl chloride with three molecules of a phosphorane represented by formula (2): A process for effectively manufacturing a poly(alkylene oxide) involves polymerizing an alkylene oxide in the presence of the above organic compound (phosphine sulfide), or in the presence of the phosphine sulfide and an active hydrogen compound selected from water and organic compounds having a partial structure of -OH or -NH-. A process for manufacturing a 1,2-dioxyethane derivative from an epoxy compound, i.e. manufacturing a 1,2-dioxyethane derivative involves reacting an epoxy compound with a carboxylate, carboxylic anhydride, carbonate or phenol compound, respectively, in the presence of the phosphine sulfide.

  一种可溶于有机溶剂、在制备或处理过程中不会出现问题并具有催化活性的碱性有机化合物是硫化膦，其代表式为（1）： 式（1）代表的硫化膦是由一分子硫代磷酰氯与三分子式（2）代表的磷烷反应制得的： 一种有效制造聚环氧亚烷烃的工艺是在上述有机化合物（硫化膦）存在下，或在硫化膦和选 自水和部分结构为-OH 或-NH-的有机化合物的活性氢化合物存在下，聚合环氧亚烷烃。 由环氧化合物制造 1，2-二氧乙烷衍生物的工艺，即制造 1，2-二氧乙烷衍生物的工艺包括在硫化膦存在下，环氧化合物分别与羧酸盐、羧酸酐、碳酸盐或苯酚化合物反应。
• US6153794A
  申请人：——

  公开号：US6153794A

  公开（公告）日：2000-11-28
• Moir, Chemisches Zentralblatt, 1913, vol. 84, # II, p. 1665
  作者：Moir

  DOI：——

  日期：——