2-(Benzhydrylamino)-2-oxoethyl 4-morpholinecarbodithioate

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-(Benzhydrylamino)-2-oxoethyl 4-morpholinecarbodithioate
• 英文别名: [2-(benzhydrylamino)-2-oxoethyl] morpholine-4-carbodithioate
• 化学式: C₂₀H₂₂N₂O₂S₂
• 分子量: 386.539
• InChiKey: MIRDXCUEZFEGAN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  26
• 可旋转键数：
  6
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.3
• 拓扑面积：
  99
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  二苯甲胺 在 三乙胺 作用下， 以 丙酮 、 苯 为溶剂， 反应 5.0h， 生成 2-(Benzhydrylamino)-2-oxoethyl 4-morpholinecarbodithioate
  参考文献：
  名称：

  SYNTHESIS OF SOME DITHIOCARBAMATE DERIVATIVES AND THEIR ANTIMICROBIAL ACTIVITY

  摘要：

  Some new, 2-[(N-substituted aminothiocarbonylthio)acetyl]aminothiazole, N-substituted aminothiocarbonylthioacetylaminodiphenylmethane and 9-[(N-substituted aminothiocarbonylthio)acetyl]aminofluorene derivatives were synthesized by reacting 2-(chloroacetyl) aminothiazole, chloroacetylaminodiphenylmethane, and 9-(chloroacetyl)aminothiazole, with secondary amine dithiocarbamate derivatives in acetone respectively. The structure elucidation of the compounds was performed by IR, H-1-NMR, and FAB(+)-MS spectral data. The substances were tested for their antimicrobial activity.

  DOI：

  10.1080/10426500490463664

文献信息

• SYNTHESIS OF SOME DITHIOCARBAMATE DERIVATIVES AND THEIR ANTIMICROBIAL ACTIVITY
  作者：Zafer Asim Kaplancıli、Gülhan Turan-Zitouni、Gilbert Revial、Gökalp Işcan

  DOI：10.1080/10426500490463664

  日期：2004.7.1

  Some new, 2-[(N-substituted aminothiocarbonylthio)acetyl]aminothiazole, N-substituted aminothiocarbonylthioacetylaminodiphenylmethane and 9-[(N-substituted aminothiocarbonylthio)acetyl]aminofluorene derivatives were synthesized by reacting 2-(chloroacetyl) aminothiazole, chloroacetylaminodiphenylmethane, and 9-(chloroacetyl)aminothiazole, with secondary amine dithiocarbamate derivatives in acetone respectively. The structure elucidation of the compounds was performed by IR, H-1-NMR, and FAB(+)-MS spectral data. The substances were tested for their antimicrobial activity.