8-ethoxycarbonyloctyl 2,3,5,6-tetra-O-benzoyl-β-D-galactofuranoside | 417717-59-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: 8-ethoxycarbonyloctyl 2,3,5,6-tetra-O-benzoyl-β-D-galactofuranoside
• 英文别名: [(2R)-2-benzoyloxy-2-[(2S,3S,4R,5R)-3,4-dibenzoyloxy-5-(9-ethoxy-9-oxononoxy)oxolan-2-yl]ethyl] benzoate
• CAS: 417717-59-0
• 化学式: C₄₅H₄₈O₁₂
• 分子量: 780.869
• InChiKey: RLJLWMLDBPVIPU-SQWHKKNSSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  9.2
• 重原子数：
  57
• 可旋转键数：
  26
• 环数：
  5.0
• sp3杂化的碳原子比例：
  0.36
• 拓扑面积：
  150
• 氢给体数：
  0
• 氢受体数：
  12

反应信息

• 作为反应物：
  描述：

  甲醇 、 8-ethoxycarbonyloctyl 2,3,5,6-tetra-O-benzoyl-β-D-galactofuranoside 在 sodium 作用下， 反应 24.0h， 以93%的产率得到8-methoxycarbonyloctyl β-D-galactofuranoside
  参考文献：
  名称：

  A NEW APPROACH TO A DISACCHARIDIC HAPTEN CONTAINING A GALACTOFURANOSYL ENTITY

  摘要：

  A short synthetic entry into the disaccharidic hapten beta-D-Galf-(1-->3)-alpha-D-Manp-O(CH2)(8)CO2Me containing a galactofuranosyl entity at the non-reducing part is described. The synthetic scheme was designed in such a way that each required building block could be obtained by minimizing the number of chemical and purification steps. Indeed, compound 8 was obtained according to a four step-one pot preparation.

  DOI：

  10.1081/car-100108662
• 作为产物：
  描述：

  n-octyl D-galactofuranoside 在 N-碘代丁二酰亚胺 、 三氟甲磺酸三甲基硅酯 、 4 A molecular sieve 作用下， 以 吡啶 、 二氯甲烷 为溶剂， 反应 3.58h， 生成 8-ethoxycarbonyloctyl 2,3,5,6-tetra-O-benzoyl-β-D-galactofuranoside
  参考文献：
  名称：

  A NEW APPROACH TO A DISACCHARIDIC HAPTEN CONTAINING A GALACTOFURANOSYL ENTITY

  摘要：

  A short synthetic entry into the disaccharidic hapten beta-D-Galf-(1-->3)-alpha-D-Manp-O(CH2)(8)CO2Me containing a galactofuranosyl entity at the non-reducing part is described. The synthetic scheme was designed in such a way that each required building block could be obtained by minimizing the number of chemical and purification steps. Indeed, compound 8 was obtained according to a four step-one pot preparation.

  DOI：

  10.1081/car-100108662

文献信息

• A NEW APPROACH TO A DISACCHARIDIC HAPTEN CONTAINING A GALACTOFURANOSYL ENTITY
  作者：Vincent Ferrières、Myriam Roussel、Muriel Gelin、Daniel Plusquellec

  DOI：10.1081/car-100108662

  日期：2001.12.31

  A short synthetic entry into the disaccharidic hapten beta-D-Galf-(1-->3)-alpha-D-Manp-O(CH2)(8)CO2Me containing a galactofuranosyl entity at the non-reducing part is described. The synthetic scheme was designed in such a way that each required building block could be obtained by minimizing the number of chemical and purification steps. Indeed, compound 8 was obtained according to a four step-one pot preparation.