2',2''-Dimethoxy-[1,3';1',1'';3'',1''']quaterphenyl | 21473-04-1

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2',2''-Dimethoxy-[1,3';1',1'';3'',1''']quaterphenyl
• 英文别名: 2-Methoxy-1-(2-methoxy-3-phenylphenyl)-3-phenylbenzene
• CAS: 21473-04-1
• 化学式: C₂₆H₂₂O₂
• 分子量: 366.459
• InChiKey: HFZQIPVBZLIMNE-UHFFFAOYSA-N

物化性质

• 沸点：
  438.1±40.0 °C(Predicted)
• 密度：
  1.099±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  6.7
• 重原子数：
  28
• 可旋转键数：
  5
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  18.5
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2',2''-Dimethoxy-[1,3';1',1'';3'',1''']quaterphenyl 在 吡啶 、 三溴化硼 、 三氯化磷 作用下， 以 四氢呋喃 、 二氯甲烷 、 甲苯 为溶剂， 生成 phenyl 4,6-O-benzylidene-2,3-O-bis[2,9-diphenyl-[dibenzo(df)[1,3,2]dioxaphosphepinyl-11]]-β-D-glucopyranoside
  参考文献：
  名称：

  New carbohydrate bisphosphites as chiral ligands

  摘要：

  The synthesis of the 2,3-bisphosphite derivatives of phenyl 4,6-O-benzylidene-beta-D-glucopyranoside leads to new chelating ligands. Their rhodium(I) and platinum(II) complexes have been tested as catalysts for the asymmetric hydroformylation of vinyl acetate, allyl acetate and p-methoxystyrene. Good regioselectivity (>90% branched product), but an enantioselectivity of only less than or equal to 36% ee were found under mild reaction conditions (25-40 degrees C, 40-70 bar syngas). (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(97)00622-8
• 作为产物：
  描述：

  2-bromo-6-phenylanisole 在 正丁基锂 、 copper dichloride 作用下， 生成 2',2''-Dimethoxy-[1,3';1',1'';3'',1''']quaterphenyl
  参考文献：
  名称：

  New carbohydrate bisphosphites as chiral ligands

  摘要：

  The synthesis of the 2,3-bisphosphite derivatives of phenyl 4,6-O-benzylidene-beta-D-glucopyranoside leads to new chelating ligands. Their rhodium(I) and platinum(II) complexes have been tested as catalysts for the asymmetric hydroformylation of vinyl acetate, allyl acetate and p-methoxystyrene. Good regioselectivity (>90% branched product), but an enantioselectivity of only less than or equal to 36% ee were found under mild reaction conditions (25-40 degrees C, 40-70 bar syngas). (C) 1998 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0957-4166(97)00622-8

文献信息

• Ammonium Salt-Catalyzed Highly Practical <i>Ortho</i>-Selective Monohalogenation and Phenylselenation of Phenols: Scope and Applications
  作者：Xiaodong Xiong、Ying-Yeung Yeung

  DOI：10.1021/acscatal.8b00327

  日期：2018.5.4

  An ortho-selective ammonium chloride salt-catalyzed direct C–H monohalogenation of phenols and 1,1′-bi-2-naphthol (BINOL) with 1,3-dichloro-5,5-dimethylhydantoin (DCDMH) as the chlorinating agent has been developed. The catalyst loading was low (down to 0.01 mol %) and the reaction conditions were very mild. A wide range of substrates including BINOLs were compatible with this catalytic protocol. Chlorinated

  以1,3-二氯-5,5-二甲基乙内酰脲（DCDMH）作为氯化剂的邻位选择性氯化铵盐催化的苯酚和1,1'-联-2-萘酚（BINOL）的直接C–H单卤化反应具有已开发。催化剂负载量低（低至0.01mol％），反应条件非常温和。包括BINOL在内的多种底物均与该催化方案兼容。氯化的BINOL是有用的合成子，用于合成范围广泛的不容易合成的不对称3-芳基BINOL。另外，相同的催化体系可以促进酚的邻位选择性硒化。
• Synthetic Approaches to Zigzag-Shaped Oligophenylene Strands Laterally Decorated with Hydroxy Functions
  作者：Carine Diebold、David Michael Weekes、Maria Torres Navarrete、Pierre Mobian、Nathalie Kyritsakas、Marc Henry

  DOI：10.1002/ejoc.201001058

  日期：2010.12

  Two nanosized zigzag-shaped oligophenylene strands incorporating 2,2′-biphenol units were prepared by Suzuki–Miyaura coupling methodology. The two strands are made up of ten and seven phenyl rings, respectively. Two synthetic pathways were evaluated. The first involved the preparation of the target oligophenylene molecules by a sequential approach, whereas the second entailed the formation of the precursors

  通过 Suzuki-Miyaura 偶联方法制备了两条包含 2,2'-联苯酚单元的纳米级锯齿形低聚亚苯基链。两条链分别由十个和七个苯环组成。评价了两种合成途径。第一个涉及通过顺序方法制备目标低聚亚苯基分子，而第二个涉及以一步方式形成目标化合物的前体。讨论并比较了这两种方法的效率。