2-hydroxy-3-ethylsulfonylpyridine | 186583-52-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-hydroxy-3-ethylsulfonylpyridine
• 英文别名: 3-ethylsulfonyl-1H-pyridin-2-one
• CAS: 186583-52-8
• 化学式: C₇H₉NO₃S
• 分子量: 187.219
• InChiKey: FMYNCGIVLJCMRD-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0
• 重原子数：
  12
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.29
• 拓扑面积：
  71.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  重氮甲烷 、 2-hydroxy-3-ethylsulfonylpyridine 以 甲醇 、 乙醚 为溶剂， 反应 2.0h， 生成 3-Ethanesulfonyl-1-methyl-1H-pyridin-2-one 、 3-Ethanesulfonyl-2-methoxy-pyridine
  参考文献：
  名称：

  Soil Metabolism of the Herbicide Rimsulfuron under Laboratory and Field Conditions

  摘要：

  Procedures were developed for soil analysis of rimsulfuron and its metabolites by means of GC-ECD, GC-FPD and GC-MS with a detection limit of 1 mu g of rimsulfuron equivalents per kilogram of dry soil, after purification of the soil extracts by TLC. Soil containing an exaggerated rimsulfuron concentration was incubated in the laboratory, in order to adjust the analytical procedures. To evaluate the role of different manuring managements, rimsulfuron was applied postemergence (10 g ha(-1) on a corn field in 1994 and 1995) on plots treated with (1) green manure, pig slurry applied in (2) November and (3) March, and cow manure applied in (4) November and (5) March and (6) untreated control plots without organic fertilizer. Neither rimsulfuron nor its metabolites were detected at soil depths lower than 8 cm. The results show that manure managements prolong rimsulfuron half-life in the 0-8 cm surface soil layer from a minimum of 14 days (control) to a maximum of 46 days (pig slurry in March). At corn harvest, rimsulfuron and its metabolites were not detected in soil. Similar soil degradation pathways were observed in the field as in the laboratory. N-(4,6-Dimethoxypyrimidin-2-yl)-N-[3-(ethylsulfonyl)-2-pyridinyl]urea 2 was a transient soil degradation product. N-[3-(ethylsulfonyl)-2-pyridinyl]-4,6-dimethoxy-2-pyrimidineamine 3 attained a maximum soil concentration after 20 days of incubation and then progressively disappeared and could not be detected after 40 days. The high-molecular weight amine 3 did not accumulate in soil, eliminating the concern for potential formation of nitroso amino compounds. 2-Hydroxy-3-(ethylsulfonyl)pyridine 4 became the major rimsulfuron soil degradation product. The soil concentrations increased and attained a maximum after 40 days of incubation and then decreased; its isomerization into 2-pyridone, followed by hydrolysis, could transform it into low molecular weight nontoxic products. The concentrations of 2-amino-4,6-dimethoxypyrimidine 5 were somewhat lower than those of compound 4.

  DOI：

  10.1021/jf9606161
• 作为产物：
  描述：

  2-氯-3-(乙基磺酰基)吡啶 在 盐酸 、 potassium phtalimide 、 一水合肼 、 sodium nitrite 作用下， 以 乙醇 、 N,N-二甲基甲酰胺 为溶剂， 反应 11.0h， 生成 2-hydroxy-3-ethylsulfonylpyridine
  参考文献：
  名称：

  Rouchaud, J.; Neus, O.; Moulard, C., Bulletin des Societes Chimiques Belges, 1997, vol. 106, # 3, p. 151 - 158

  摘要：

  DOI：

文献信息

• Rouchaud, J.; Neus, O.; Moulard, C., Bulletin des Societes Chimiques Belges, 1997, vol. 106, # 1, p. 59 - 66
  作者：Rouchaud, J.、Neus, O.、Moulard, C.

  DOI：——

  日期：——
• Rouchaud, J.; Neus, O.; Moulard, C., Bulletin des Societes Chimiques Belges, 1997, vol. 106, # 3, p. 151 - 158
  作者：Rouchaud, J.、Neus, O.、Moulard, C.

  DOI：——

  日期：——
• Soil Metabolism of the Herbicide Rimsulfuron under Laboratory and Field Conditions
  作者：Jean Rouchaud、Olivier Neus、Dany Callens、Robert Bulcke

  DOI：10.1021/jf9606161

  日期：1997.8.1

  Procedures were developed for soil analysis of rimsulfuron and its metabolites by means of GC-ECD, GC-FPD and GC-MS with a detection limit of 1 mu g of rimsulfuron equivalents per kilogram of dry soil, after purification of the soil extracts by TLC. Soil containing an exaggerated rimsulfuron concentration was incubated in the laboratory, in order to adjust the analytical procedures. To evaluate the role of different manuring managements, rimsulfuron was applied postemergence (10 g ha(-1) on a corn field in 1994 and 1995) on plots treated with (1) green manure, pig slurry applied in (2) November and (3) March, and cow manure applied in (4) November and (5) March and (6) untreated control plots without organic fertilizer. Neither rimsulfuron nor its metabolites were detected at soil depths lower than 8 cm. The results show that manure managements prolong rimsulfuron half-life in the 0-8 cm surface soil layer from a minimum of 14 days (control) to a maximum of 46 days (pig slurry in March). At corn harvest, rimsulfuron and its metabolites were not detected in soil. Similar soil degradation pathways were observed in the field as in the laboratory. N-(4,6-Dimethoxypyrimidin-2-yl)-N-[3-(ethylsulfonyl)-2-pyridinyl]urea 2 was a transient soil degradation product. N-[3-(ethylsulfonyl)-2-pyridinyl]-4,6-dimethoxy-2-pyrimidineamine 3 attained a maximum soil concentration after 20 days of incubation and then progressively disappeared and could not be detected after 40 days. The high-molecular weight amine 3 did not accumulate in soil, eliminating the concern for potential formation of nitroso amino compounds. 2-Hydroxy-3-(ethylsulfonyl)pyridine 4 became the major rimsulfuron soil degradation product. The soil concentrations increased and attained a maximum after 40 days of incubation and then decreased; its isomerization into 2-pyridone, followed by hydrolysis, could transform it into low molecular weight nontoxic products. The concentrations of 2-amino-4,6-dimethoxypyrimidine 5 were somewhat lower than those of compound 4.