Methyl-2-oxo-trans-decalyl-9-acetat | 55498-55-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 羧酸及其衍生物
• 英文名称: Methyl-2-oxo-trans-decalyl-9-acetat
• 英文别名: methyl 2-[(4aS,8aS)-6-oxo-1,2,3,4,5,7,8,8a-octahydronaphthalen-4a-yl]acetate
• CAS: 55498-55-0
• 化学式: C₁₃H₂₀O₃
• 分子量: 224.3
• InChiKey: KEGZKZRIIVNYFD-GWCFXTLKSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  2.2
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为产物：
  描述：

  甲醇 、 (2'aR,5'aS,9'aS)-spiro[1,3-dioxolane-2,3'-2a,4,5,5a,6,7,8,9-octahydro-1H-cyclobuta[j]naphthalene]-2'-one 在 盐酸 作用下， 反应 2.0h， 生成 Methyl-2-oxo-trans-decalyl-9-acetat
  参考文献：
  名称：

  Unprecedented Grob-type fragmentation of 5-dioxolan-bicyclo[4.2.0]octan-2-ones into 3-(methoxycarbonylmethyl)cyclohexanones

  摘要：

  The unprecedented Grob-type fragmentations of 5-dioxolan-bicyclo[4.2.0]octan-2-ones 1 into 3-(methoxycarbonylmethtl)cyclohexanes 2 are described. This fragmentation, in combination with the allene photoannelation used to produce compounds 1, might constitute an indirect way for achieving: conjugate addition of methyl acetate; new syntheses of kaurane, stemarane and thirsiflorane diterpenes might be also envisaged from 2c and 2d. (C) 1997 Elsevier Science Ltd.

  DOI：

  10.1016/s0040-4039(97)00657-6

文献信息

• Unprecedented Grob-type fragmentation of 5-dioxolan-bicyclo[4.2.0]octan-2-ones into 3-(methoxycarbonylmethyl)cyclohexanones
  作者：Marzia De Giacomo、Rinaldo Marini Bettolo、Rita Scarpelli

  DOI：10.1016/s0040-4039(97)00657-6

  日期：1997.5

  The unprecedented Grob-type fragmentations of 5-dioxolan-bicyclo[4.2.0]octan-2-ones 1 into 3-(methoxycarbonylmethtl)cyclohexanes 2 are described. This fragmentation, in combination with the allene photoannelation used to produce compounds 1, might constitute an indirect way for achieving: conjugate addition of methyl acetate; new syntheses of kaurane, stemarane and thirsiflorane diterpenes might be also envisaged from 2c and 2d. (C) 1997 Elsevier Science Ltd.