2-Nitro-4-trifluormethylbenzolsulfonsaeure | 445-74-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2-Nitro-4-trifluormethylbenzolsulfonsaeure
• 英文别名: 2-Nitro-4-(trifluoromethyl)benzenesulfonic acid
• CAS: 445-74-9
• 化学式: C₇H₄F₃NO₅S
• 分子量: 271.174
• InChiKey: FIJXHKWGNPMYCD-UHFFFAOYSA-N

物化性质

• 密度：
  1.721±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.1
• 重原子数：
  17
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  109
• 氢给体数：
  1
• 氢受体数：
  8

反应信息

• 作为反应物：
  描述：

  2-Nitro-4-trifluormethylbenzolsulfonsaeure 、 环己胺 以 四氢呋喃 为溶剂， 反应 12.0h， 以62%的产率得到环己基-(2-硝基-4-三氟甲基-苯基)-胺
  参考文献：
  名称：

  磺酸的异丙基亲核取代合成邻硝基硝基芳基胺

  摘要：

  描述了一种温和，有效和环保的方法，该方法用于通过邻氨基芳基的ipso亲核芳基取代反应，由邻硝基芳基磺酸合成邻硝基芳基胺。无需任何金属，活化剂或有毒氧化剂的帮助，即可在室温下以高收率获得产品。该方法可用于无消旋地合成N-芳基氨基酸酯。

  DOI：

  10.1021/acs.orglett.8b03730
• 作为产物：
  描述：

  4-氟-3-硝基三氟甲苯 在 sodium sulfite 作用下， 生成 2-Nitro-4-trifluormethylbenzolsulfonsaeure
  参考文献：
  名称：

  用三氟甲基取代的芳基卤化物和磺酸盐修饰人血清白蛋白。

  摘要：

  DOI：

  10.1021/ja00834a029

文献信息

• Process for producing polymer compounds by elimination reaction
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP1344783A1

  公开（公告）日：2003-09-17

  A process for producing a polymer compound having a double bond in a side chain, wherein a functional group represented by the following formula (1) is subjected to an elimination reaction to form the polymer compound which includes another functional group having the double bond in the side chain thereof represented by the following formula (2):    wherein, in the formulae, A1 represents an oxygen atom, a sulfur atom or -N(R4)-; R1, R2, R3 and R4 each independently represent a hydrogen atom or a monovalent organic group; and X1 and Z1 each represent a group that is removable by the elimination reaction.

  一种生产侧链中具有双键的聚合物化合物的工艺，其中下式(1)表示的官能团经过消去反应形成聚合物化合物，该聚合物化合物包括下式(2)表示的侧链中具有双键的另一个官能团： 其中，在式中，A1 代表氧原子、硫原子或-N(R4)-；R1、R2、R3 和 R4 各自独立地代表氢原子或一价有机基团；以及 X1 和 Z1 各自代表通过消去反应可消去的基团。
• Polymer having polymerizable group, polymerizable composition, planographic printing plate precursor, and planographic printing method using the same
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：EP1634898A2

  公开（公告）日：2006-03-15

  A polymer having a polymerizable group and an alkyleneoxy groups on side chains thereof, and a polymerizable composition containing the polymer. The polymerizable composition preferably contains a polymerizable compound and a polymerization initiator. Also provided is a planographic printing plate precursor having a polymerizable layer on a hydrophilic support, the polymerizable layer containing a polymer having a polymerizable on a side chain thereof. The planographic printing plate precursor can form an image without being subjected to an alkali development. An undercoat layer containing a specific copolymer may be provided between the support and the photopolymerizable layer.

  一种聚合物，其侧链上具有可聚合基团和烷氧基，以及一种含有该聚合物的可聚合组合物。可聚合组合物最好含有可聚合化合物和聚合引发剂。此外，还提供了一种平版印刷板前体，它在亲水性支撑物上具有可聚合层，可聚合层含有侧链上具有可聚合基团的聚合物。这种平版印刷板前体无需经过碱显影即可形成图像。在支承层和可光聚合层之间可设置一个含有特定共聚物的底涂层。
• PLANOGRAPHIC PRINTING PLATE PRECURSOR USING A POLYMERIZABLE COMPOSITION
  申请人：FUJIFILM Corporation

  公开号：EP3182204A1

  公开（公告）日：2017-06-21

  A polymer having a polymerizable group and an alkyleneoxy groups on side chains thereof, and a polymerizable composition containing the polymer. The polymerizable composition preferably contains a polymerizable compound and a polymerization initiator. Also provided is a planographic printing plate precursor having a polymerizable layer on a hydrophilic support, the polymerizable layer containing a polymer having a polymerizable on a side chain thereof. The planographic printing plate precursor can form an image without being subjected to an alkali development. An undercoat layer containing a specific copolymer may be provided between the support and the photopolymerizable layer.

  一种聚合物，其侧链上具有可聚合基团和烷氧基，以及一种含有该聚合物的可聚合组合物。可聚合组合物最好含有可聚合化合物和聚合引发剂。此外，还提供了一种平版印刷板前体，它在亲水性支撑物上具有可聚合层，可聚合层含有侧链上具有可聚合基团的聚合物。这种平版印刷板前体无需经过碱显影即可形成图像。在支承层和可光聚合层之间可设置一个含有特定共聚物的底涂层。
• METHOD FOR NON-ENZYMATIC COMBINATION OF NUCLEIC ACID CHAINS
  申请人：Japan Science and Technology Agency

  公开号：EP3187584A1

  公开（公告）日：2017-07-05

  Provided, as a technique for binding a nucleic acid chain and a nucleic acid chain by a natural structure or an analogous structure thereto, is a non-enzymatic nucleic acid chain binding method, which is a method for binding a nucleic acid chain and a nucleic acid chain not via an enzymatic reaction, including a step of reacting a nucleic acid chain having a phosphorothioate group and a nucleic acid chain having a hydroxyl group or amino group in the presence of an electrophile.

  作为一种通过天然结构或类似结构结合核酸链和核酸链的技术，提供了一种非酶结合核酸链的方法，它是一种不通过酶反应结合核酸链和核酸链的方法，包括在亲电子体存在的情况下，使具有硫代磷酸基的核酸链和具有羟基或氨基的核酸链发生反应的步骤。
• Process for producing polymer compound
  申请人：FUJI PHOTO FILM CO., LTD.

  公开号：US20030215745A1

  公开（公告）日：2003-11-20

  A process for producing a polymer compound having a double bond in a side chain, wherein a functional group represented by the following formula (1) is subjected to an elimination reaction to form the polymer compound which includes another functional group having the double bond in the side chain thereof represented by the following formula (2): 1 wherein, in the formulae, A 1 represents an oxygen atom, a sulfur atom or —N(R 4 )—; R 1 , R 2 , R 3 and R 4 each independently represent a hydrogen atom or a monovalent organic group; and X 1 and Z 1 each represent a group that is removable by the elimination reaction.

  一种生产侧链中含有双键的高分子化合物的工艺，其中由下式（1）表示的官能团经过消去反应形成高分子化合物，该高分子化合物包括由下式（2）表示的侧链中含有双键的另一个官能团： 1 式中，A 1 代表氧原子、硫原子或-N(R 4 )-; R 1 , R 2 , R 3 和 R 4 各自独立地代表一个氢原子或一个一价有机基团；以及 X 1 和 Z 1 各自代表可通过消去反应去除的基团。