5-pentyl-barbituric acid | 14077-80-6

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 二嗪类
• 英文名称: 5-pentyl-barbituric acid
• 英文别名: 5-Pentyl-barbitursaeure；5-Pentylpyrimidine-2,4,6(1h,3h,5h)-trione；5-pentyl-1,3-diazinane-2,4,6-trione
• CAS: 14077-80-6
• 化学式: C₉H₁₄N₂O₃
• 分子量: 198.222
• InChiKey: KWYGDMBOVSXLOK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  14
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.67
• 拓扑面积：
  75.3
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  5-pentyl-barbituric acid 生成 2,4-Dimethoxy-5-pentylpyrimidine
  参考文献：
  名称：

  SANEYOSHI, MINEO;WATANABE, SHINICHI, CHEM. AND PHARM. BULL., 36,(1988) N 7, C. 2673-2678

  摘要：

  DOI：
• 作为产物：
  描述：

  尿素 、 alkaline earth salt of/the/ methylsulfuric acid 在 sodium ethanolate 作用下， 生成 5-pentyl-barbituric acid
  参考文献：
  名称：

  NEW DERIVATIVES OF BARBITURIC ACID

  摘要：

  DOI：

  10.1021/ja01394a041

文献信息

• [EN] COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT<br/>[FR] COMPOSITIONS, MÉTHODES D'UTILISATION ET MÉTHODES DE TRAITEMENT
  申请人：UNIV NEW ORLEANS

  公开号：WO2015048634A1

  公开（公告）日：2015-04-02

  Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the antimicrobial agent, methods of treatment of an infection, methods of treatment using compositions or pharmaceutical compositions, and the like.

  本公开的实施例提供了包括抗微生物剂的组合物、包括抗微生物剂的药物组合物、治疗感染的方法、使用组合物或药物组合物进行治疗的方法等。
• COMPOSITIONS, METHODS OF USE, AND METHODS OF TREATMENT
  申请人：THE UNIVERSITY OF NEW ORLEANS

  公开号：US20160235752A1

  公开（公告）日：2016-08-18

  Embodiments of the present disclosure provide for compositions including an antimicrobial agent, pharmaceutical compositions including the antimicrobial agent, methods of treatment of an infection, methods of treatment using compositions or pharmaceutical compositions, and the like.

  本公开的实施例提供了包括抗微生物剂的组合物、包括抗微生物剂的药物组合物、治疗感染的方法、使用组合物或药物组合物的治疗方法等。
• Method, means and kit for infiltrating enamel lesions
  申请人：Charité Universitätsmedizin Berlin

  公开号：EP2476404A1

  公开（公告）日：2012-07-18

  The present invention refers to a method of infiltrating enamel for the prevention and/or treatment of carious lesions comprising (a) exposing an enamel area to a conditioner comprising hydrochloric acid; (b) exposing the conditioned enamel area to an infiltrant; and (c) curing the infiltrant. The present invention further refers to a kit for carrying out the method of infiltrating enamel, which comprises a conditioner comprising hydrochloric acid and an infiltrant comprising at least one low viscous dental resin. Alternatively, the kit comprises ready-to-use means for carrying out the method of infiltrating enamel, e.g. application strips with delivery pads soaked with conditioner or infiltrant.; The present invention also refers to a method for identifying an infiltrant by calculation of the penetration coefficient, and to an infiltrant identified by the method having a penetration coefficient of >50 cm/s or comprising a low viscous light curing resin having a penetration coefficient of >50 cm/s.

  本发明涉及一种用于预防和/或治疗龋损的釉质浸润方法，该方法包括：(a) 将釉质区域暴露于由盐酸组成的调节剂中；(b) 将调节后的釉质区域暴露于浸润剂中；(c) 将浸润剂固化。本发明还涉及一种用于实施釉质浸润方法的试剂盒，该试剂盒包括由盐酸组成的调节剂和由至少一种低粘度牙科树脂组成的浸润剂。本发明还涉及一种通过计算渗透系数来确定渗透剂的方法，以及一种通过该方法确定的渗透剂，其渗透系数大于 50 cm/s，或包含一种低粘度光固化树脂，其渗透系数大于 50 cm/s。
• Curable compositions with antimicrobial properties
  申请人：——

  公开号：US20010056133A1

  公开（公告）日：2001-12-27

  Novel curable compositions are disclosed which include a water-insoluble antimicrobial agent. The curable compositions are useful in inhibiting the growth of bacteria on the surface of the curable composition, within the curable compositions and in a volume adjacent to the curable composition.

  本发明公开了新型可固化组合物，其中包括一种水不溶性抗菌剂。这种可固化组合物有助于抑制细菌在可固化组合物表面、可固化组合物内部以及可固化组合物邻近体积内的生长。
• Compositions for making an artificial prosthesis
  申请人：——

  公开号：US20020086915A1

  公开（公告）日：2002-07-04

  Novel compositions and methods are disclosed for manufacturing an artificial prosthesis, whether for medical, dental or cosmetic use. The compositions include a family of monomeric esters having increased solvency and decreased volatility.

  本发明公开了用于制造人工假体（无论是医疗、牙科还是美容用途）的新型组合物和方法。这些组合物包括一系列具有更高溶解度和更低挥发性的单体酯。