5-phenyl-2-(3-phenyl-propyl)-valeric acid | 262608-65-1

• 分子结构分类: 有机化合物 - 苯丙烷和聚酮 - 二芳基庚烷
• 英文名称: 5-phenyl-2-(3-phenyl-propyl)-valeric acid
• 英文别名: 5-Phenyl-2-(3-phenyl-propyl)-valeriansaeure；5-phenyl-2-(3-phenyl-propyl)-pentanoic acid；5-phenyl-2-(3-phenylpropyl)pentanoic acid
• CAS: 262608-65-1
• 化学式: C₂₀H₂₄O₂
• 分子量: 296.409
• InChiKey: ZMGGURYXNAMNDU-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  5.5
• 重原子数：
  22
• 可旋转键数：
  9
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.35
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  5-phenyl-2-(3-phenyl-propyl)-valeric acid 在 溶剂黄146 、 铂 作用下， 生成 5-cyclohexyl-2-(3-cyclohexyl-propyl)-valeric acid
  参考文献：
  名称：

  The Catalytic Hydrogenation of the Benzene Nucleus. I. The Hydrogenation of Phenyl-substituted Aliphatic Acids

  摘要：

  DOI：

  10.1021/ja01218a037
• 作为产物：
  描述：

  2,2-bis(3-phenylpropyl) malonic acid 生成 5-phenyl-2-(3-phenyl-propyl)-valeric acid
  参考文献：
  名称：

  Ramart-Lucas; Hoch, Annales de Chimie (Cachan, France), 1932, vol. <10> 17, p. 207,244

  摘要：

  DOI：

文献信息

• Substituted bicyclic compounds for treating multidrug resistance
  申请人：——

  公开号：US20020082262A1

  公开（公告）日：2002-06-27

  Substituted bicyclic compounds for treating multidrug resistance are disclosed. Compositions and methods of use for the substituted bicyclic compounds are disclosed. Suitable substituted bicyclic compounds include: 1

  公开了用于治疗多药耐药的取代双环化合物。公开了取代双环化合物的组合物和使用方法。适合的取代双环化合物包括：1
• Substituted heterocyclic compounds for treating multidrug resistance
  申请人：The Procter Gamble Co.

  公开号：US20020099215A1

  公开（公告）日：2002-07-25

  Substituted heterocyclic compounds are disclosed. The compounds are useful for treating multidrug resistance. The compounds can be formulated in compositions with a carrier and, optionally, a therapeutic agent. One suitable substituted heterocyclic compound has the formula: 1

  本发明公开了替代杂环化合物，这些化合物可用于治疗多药耐药性。这些化合物可以与载体和（或）治疗剂一起配制成组合物。其中一种适用的替代杂环化合物的化学式为：1。
• Compounds having heterocyclic groups containing two nitrogen atoms for treating multidrug resistance
  申请人：——

  公开号：US20020115659A1

  公开（公告）日：2002-08-22

  Compounds having heterocyclic groups containing two nitrogen atoms are disclosed. The compounds are useful for treating multidrug resistance. The compounds can be formulated in compositions with a carrier and, optionally, a therapeutic agent. One suitable compound has the formula: 1

  公开了含有两个氮原子的杂环基团的化合物。这些化合物对于治疗多药耐药性很有用。这些化合物可以与载体和可选的治疗剂一起制成组合物。一个合适的化合物的化学式如下：1。
• SUBSTITUTED HETEROCYCLIC COMPOUNDS FOR TREATING MULTIDRUG RESISTANCE
  申请人：Degenhardt Raymond Charles

  公开号：US20060223853A1

  公开（公告）日：2006-10-05

  Compounds suitable for treating multidrug resistance and methods for their preparation and use are disclosed. The compounds are represented by the following formula: or an optical isomer, diastereomer, enantiomer or pharmaceutically acceptable salt thereof.

  本发明揭示了适用于治疗多药耐药的化合物及其制备和使用方法。该化合物由以下式表示：或其光学异构体，对映异构体，对映体或其药学上可接受的盐。
• Substituted six-membered heterocyclic compounds useful for treating multidrug resistance and compositions and methods thereof
  申请人：The Procter & Gamble Co.

  公开号：US06376514B1

  公开（公告）日：2002-04-23

  Substituted heterocyclic compounds are disclosed. The compounds are useful for treating multidrug resistance. The compounds can be formulated in compositions with a carrier and, optionally, a therapeutic agent. One suitable substituted heterocyclic compound has the formula:

  本发明揭示了替代杂环化合物。这些化合物可用于治疗多药耐药。这些化合物可以与载体和（或）治疗剂组成配方。一个合适的替代杂环化合物的化学式如下：