α,α'-bis(diphenylphosphoryl) dimethyl ether

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: α,α'-bis(diphenylphosphoryl) dimethyl ether
• 英文别名: 1,3-bis(diphenylphosphinoyl)-3-oxapropane；1,3-bis(diphenylphosphoryl)-2-oxapropane；Bis(diphenylphosphinylmethyl) ether；[diphenylphosphorylmethoxymethyl(phenyl)phosphoryl]benzene
• 化学式: C₂₆H₂₄O₃P₂
• mdl: MFCD00778152
• 分子量: 446.422
• InChiKey: KNSKBATZOAOFSB-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.8
• 重原子数：
  31
• 可旋转键数：
  8
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  43.4
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  neodymium(III) nitrate 、 α,α'-bis(diphenylphosphoryl) dimethyl ether 以 甲苯 、 乙腈 为溶剂， 生成 [Nd₂(Ph₂P(O)CH₂OCH₂P(O)Ph₂)(NO₃)₆]*1.99H2O
  参考文献：
  名称：

  Phosphoryl Podands Ph2P(O)CH2O(CH2CH2O)nCH2P(O)Ph2 (Ln, n = 0–5): Complexation and Extraction of Rare Earth Elements. Crystal Structures of [Ln2L03(NO3)6] · xH2O (Ln = Nd, x = 1.99; Ln = Eu, x = 1; Ln = Er, x = 6.5; Ln = Lu, x = 6) and [LnL2(NO3)3(H2O)] (Ln = Nd, Er)

  摘要：

  Extraction of rare earth elements with bis(diphenylphosphorylmethyl) ethers of oligoethylene glycols Ph2P(O)CH2O(CH2CH2O)(n)CH2P(O)Ph-2 (L-n, n = 0-5) in 1,1,7-trihydrododecafluoroheptanol-water system with variable HNO3 concentration from 0.5 to 6 mol/L has been studied Complexes of Nd, Eu, Lu, and Er nitrates with L-0 and L-2 have been obtained. Crystal structures of [Ln(2)L(3)(o)(NO3)(6)]center dot xH(2)O (Ln = Nd, x = 1.99; Ln = Eu, x = 1; Ln = Er, x = 6.5; Ln = Lu, x = 6) and [LnL(2)(NO3)(3)(H2O)] (Ln = Nd, Er) have been studied by X-ray diffraction, IR spectroscopy, and thermogravimetry. Correlation between X-ray diffraction and extraction data has been revealed.

  DOI：

  10.1134/s0036023618100169
• 作为产物：
  描述：

  (二苯基磷酰基)甲醇 、 (diphenylphosphoryl)methyl p-toluenesulfonate 在 caesium carbonate 作用下， 以 1,4-二氧六环 为溶剂， 反应 10.0h， 以85%的产率得到α,α'-bis(diphenylphosphoryl) dimethyl ether
  参考文献：
  名称：

  低聚乙二醇双（二苯基磷酰基甲基）醚的合成，络合性能和选择性。1,3-双（二苯基磷酰基）-2-氧丙烷的晶体结构

  摘要：

  一种合成具有通式Ph 2 P（O）CH 2 O（CH 2 CH 2 O）n CH 2 P（O）Ph 2（L n，n = 0的二戊基磷酰基甲基端基的磷酰基取代的Podands的简便方法–6）描述。通过电导法测定豆荚与碱金属2，4-二硝基苯酚盐的配合物的稳定性常数。通过离子测定法评估了荚果对碱金属和碱土金属阳离子的离子选择性。通过X射线衍射分析确定了1，3-双（二苯基磷酰基）-2-氧丙烷的晶体结构。

  DOI：

  10.1134/s107036321711010x

文献信息

• Synthesis of Phosphorus-Containing Podands―Analogs of Diglycolamide Based on Diphenyl- and Dibutylphosphorylmethanol under Phase Transfer Catalysis Conditions
  作者：A. V. Kharlamov、S. K. Belus、O. I. Artyushin、N. A. Bondarenko

  DOI：10.1134/s107036321809013x

  日期：2018.9

  = Bu via OH-alkylation of phosphorylmethanols under the phase transfer conditions in the presence of Cs2CO3 was developed. Carbamoyl-substituted dimethyl ethers were synthesized via transformation of phosphorylmethanols to phosphorylmethoxyacetic acids, followed by amidation. Symmetrical bisphosphoryl substituted dimethyl ethers were obtained by reaction of phosphorylmethanols with tosyl chloride in

  一种方便的制备含磷豆荚的方法R 2 P（O）CH 2 OCH 2 X，其中X = C（O）NBu 2；P（O）R' 2，R = R'=苯基，卜，R =苯基，R'=卜经由铯的存在下，相转移条件下的phosphorylmethanols OH-烷基化2 CO 3被开发。氨基甲酰基取代的二甲醚是通过将磷酰基甲醇转化为磷酰基甲氧基乙酸，然后进行酰胺化反应而合成的。在Cs 2 CO 3存在下，使磷酰基甲醇与甲苯磺酰氯反应，得到对称的双磷酰基取代的二甲醚。在Cs 2 CO 3存在下不对称取代醚的合成由于甲苯磺酸磷酰基甲基酯的酯交换反应而复杂化，导致形成对称的副产物二甲醚。
• Polyphosphine Polyoxides as Complexing Agents of Actinides for the Removal from the Nuclear Wastes or from the Human Body
  作者：Henri-Jean Cristau、David Virieux、Jean-Luc Pirat、Eric Ansoborlo、Marie Helene Henge Napoli、François Paquet

  DOI：10.1080/10426509908546292

  日期：1999.1.1

  synthesized two kinds of polyphosphine polyoxides. The first one has ether bridge, and the second one shows PCP linkage. Complexation properties of these compounds towards minor actinides (Np, Pu and Am) have been evaluated from liquid-liquid extraction and from transport by supported liquid membranes. In decorporation experiment, some of the synthesized phosphonates exhibit in vivo good uranyl or neptunium

  我们合成了两种聚膦聚氧化物。第一个有以太桥，第二个显示PCP链接。这些化合物对微量锕系元素（Np、Pu 和 Am）的络合特性已通过液-液萃取和支撑液膜的传输进行了评估。在装饰实验中，一些合成的膦酸盐在体内表现出良好的铀或镎络合特性。
• Synthesis, complexing properties, and selectivity of bis(diphenylphosphorylmethyl) ethers of oligoethylene glycols. Crystal structure of 1,3-bis(diphenylphosphoryl)-2-oxapropane
  作者：I. S. Ivanova、V. E. Baulin、I. N. Polyakova、E. N. Pyatova、E. S. Krivorot’ko、E. N. Galkina、A. Yu. Tsivadze

  DOI：10.1134/s107036321711010x

  日期：2017.11

  A convenient method of synthesis of phosphoryl-substituted podands with dipehnylphosphorylmethyl end groups of the general formula Ph2P(O)CH2O(CH2CH2O)nCH2P(O)Ph2 (Ln, n = 0–6) is described. The stability constants of the complexes of the podands with alkali metal 2,4-dinitrophenolates were determined by conductometry. The ion-selective properties of the podands with respect to alkali and alkaline-earth

  一种合成具有通式Ph 2 P（O）CH 2 O（CH 2 CH 2 O）n CH 2 P（O）Ph 2（L n，n = 0的二戊基磷酰基甲基端基的磷酰基取代的Podands的简便方法–6）描述。通过电导法测定豆荚与碱金属2，4-二硝基苯酚盐的配合物的稳定性常数。通过离子测定法评估了荚果对碱金属和碱土金属阳离子的离子选择性。通过X射线衍射分析确定了1，3-双（二苯基磷酰基）-2-氧丙烷的晶体结构。
• Phosphoryl Podands Ph2P(O)CH2O(CH2CH2O)nCH2P(O)Ph2 (Ln, n = 0–5): Complexation and Extraction of Rare Earth Elements. Crystal Structures of [Ln2L03(NO3)6] · xH2O (Ln = Nd, x = 1.99; Ln = Eu, x = 1; Ln = Er, x = 6.5; Ln = Lu, x = 6) and [LnL2(NO3)3(H2O)] (Ln = Nd, Er)
  作者：I. N. Polyakova、E. S. Krivorot’ko、I. S. Ivanova、E. N. Pyatova、S. V. Demin、V. I. Zhilov、V. E. Baulin、A. B. Ilyukhin、A. Yu. Tsivadze

  DOI：10.1134/s0036023618100169

  日期：2018.10

  Extraction of rare earth elements with bis(diphenylphosphorylmethyl) ethers of oligoethylene glycols Ph2P(O)CH2O(CH2CH2O)(n)CH2P(O)Ph-2 (L-n, n = 0-5) in 1,1,7-trihydrododecafluoroheptanol-water system with variable HNO3 concentration from 0.5 to 6 mol/L has been studied Complexes of Nd, Eu, Lu, and Er nitrates with L-0 and L-2 have been obtained. Crystal structures of [Ln(2)L(3)(o)(NO3)(6)]center dot xH(2)O (Ln = Nd, x = 1.99; Ln = Eu, x = 1; Ln = Er, x = 6.5; Ln = Lu, x = 6) and [LnL(2)(NO3)(3)(H2O)] (Ln = Nd, Er) have been studied by X-ray diffraction, IR spectroscopy, and thermogravimetry. Correlation between X-ray diffraction and extraction data has been revealed.