difluoropyromellitic acid | 10311-26-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: difluoropyromellitic acid
• 英文别名: 3,6-Difluorpyromellith-saeure；1,2,4,5-Benzenetetracarboxylic acid, 3,6-difluoro-；3,6-difluorobenzene-1,2,4,5-tetracarboxylic acid
• CAS: 10311-26-9
• 化学式: C₁₀H₄F₂O₈
• 分子量: 290.134
• InChiKey: QIEYXOPLDWVXDS-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.2
• 重原子数：
  20
• 可旋转键数：
  4
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  149
• 氢给体数：
  4
• 氢受体数：
  10

反应信息

• 作为反应物：
  描述：

  difluoropyromellitic acid 在 乙酸酐 作用下， 反应 2.0h， 生成 1,4-Difluoro-2,3,5,6-benzenetetracarboxylic dianhydride
  参考文献：
  名称：

  苯二炔（1,2,4,5-四氢苯）：在低温氮基质中通过波长选择性光解苯四甲酸二酐的直接观察

  摘要：

  为了直接观察苯二炔，我们研究了 5 种苯四甲酸二酐衍生物在 13 K 氮基质中的波长选择性光解。在光解的第一步中，所有二酐都转化为苯二甲酸酐，并在辐照时损失了 CO 和 CO2在 308 纳米。在第二步中，苄基中间体在 266 nm 处被光解。在这些光解中，通过观察和计算的红外光谱之间的良好对应关系证实了两种苯二炔的产生，即 3,6-二氟-1,4-苯二炔和 3,6-双（三氟甲基）-1,4-苯二炔. 这些苯二炔在 266 nm 下进一步照射后转化为相应的六炔。在其他三种二酐的光解中未观察到苯二炔：仅观察到六炔作为主要的光产物。这些结果表明苯二炔首先生成然后转化为己三炔，并且苯二炔的分解效率取决于取代基。通过使用连续反应方案分析了基质中苯二炔的产生和分解的动力学。

  DOI：

  10.1021/ja017566n
• 作为产物：
  描述：

  1,4-difluoro-2,3,5,6-tetramethylbenzene 在 硝酸 、 氢氧化钾 、 potassium permanganate 作用下， 150.0 ℃ 、303.97 kPa 条件下， 反应 12.0h， 以57%的产率得到difluoropyromellitic acid
  参考文献：
  名称：

  Dmowski, Wojciech; Piasecka-Maciejewska, Krystyna, Organic Preparations and Procedures International, 1992, vol. 24, # 2, p. 194 - 197

  摘要：

  DOI：

文献信息

• ORGANIC/INORGANIC HYBRID NANOPARTICULATES MADE FROM IRON CARBOXYLATES
  申请人：Horcajada-Cortes Patricia

  公开号：US20100209354A1

  公开（公告）日：2010-08-19

  The invention relates to nanoparticles made from organometallic hybrid materials made from iron carboxylates, used for example as contrast agents. The particles can also be used for the encapsulation and vectoring of molecules of interest such as active3 pharmaceutical agents, cosmetically interesting compounds and markers. Apart from the intrinsic properties thereof for imaging, said nanoparticles give good results in terms of capacity for loading with medicaments and in biocompatibility.

  该发明涉及由铁羧酸盐制成的有机金属混合材料制成的纳米颗粒，例如用作对比剂。这些颗粒还可用于封装和导向感兴趣的分子，如活性药物、具有化妆品特性的化合物和标记物。除了其成像的固有特性外，这些纳米颗粒在药物载荷能力和生物相容性方面也表现出良好的结果。
• SOLID INORGANIC/ORGANIC HYBRID WITH MODIFIED SURFACE
  申请人：Horcajada-Cortes Patricia

  公开号：US20100226991A1

  公开（公告）日：2010-09-09

  The invention relates to solid organometallic hybrids with modified surface. Said solid may be used for example for the encapsulation and vectoring of molecules of interest such as active pharmaceutical agents, compounds of interest in cosmetics and markers, for example, contrast agents. Said solids show good results in terms of loading capacity in medicament agents and in biocompatibility.

  该发明涉及具有改性表面的固体有机金属杂化物。所述固体可以用于例如封装和载体化感兴趣的分子，如活性药物剂、化妆品中感兴趣的化合物和标记物，例如对比剂。所述固体在药物剂的装载能力和生物相容性方面表现出良好的结果。
• ORGANIC-INORGANIC HYBRID SOLID HAVING A MODIFIED OUTER SURFACE
  申请人：CENTRE NATIONAL DE LA RECHERCHE SCIENTIFIQUE-CNRS

  公开号：US20150150981A1

  公开（公告）日：2015-06-04

  The present invention concerns metal-organic hybrid solids having a modified outer surface. These solids can be used, for example, for the storage and vectoring of molecules of interest such as pharmaceutically active ingredients, compounds of interest in cosmetics and markers, for example contrast agents. These solids have good results in terms of active drug loading capacities, biocompatibility, stability and controlling the release of the active ingredients encapsulated.

  本发明涉及具有改性外表面的金属-有机混合固体。这些固体可以用于存储和载体化感兴趣的分子，例如药用活性成分、化妆品中感兴趣的化合物和标记物，例如对比剂。这些固体在活性药物装载能力、生物相容性、稳定性和控制封装的活性成分释放方面取得了良好的结果。
• Polyimide optical waveguide and method of manufacturing the same
  申请人：NIPPON TELEGRAPH AND TELEPHONE CORPORATION

  公开号：EP0616234A2

  公开（公告）日：1994-09-21

  A polyimide optical waveguide comprising a core (2) made of polyimide whose refractive index is controlled to a predetermined value by electron beam irradiation, and a cladding (1, 3) set in contact with the core and having a refractive index lower than that of the core. A polyamic acid solution is spin-coated on a substrate such as of silicon, and is thermally cured to form a polyimide layer. An electron beam is irradiated on the entire surface of the polyimide layer to change the refractive index to a predetermined value. An electron beam-absorbed dose of the polyimide layer depends on the composition of the polyimide, an energy of the electron beam, and the applied amount of the electron beam irradiation. The refractive index changes in accordance therewith approximately. This polyimide layer irradiated with the electron beam is used as a core layer. Next, the same polyamic acid solution is spin-coated on the core layer, and is thermally cured. The material is separated from the substrate to obtain a polyimide film of a two-layer structure. Then, the polyimide film of a two-layer structure is made to reverse and the irradiated polyimide layer is made to the upper surface. The lower surface of the reversed film is adhered by a method such as a thermo-compression bonding on the other silicon substrate. Next, the core layer is patterned into a desired shape, for example, a rectangular shape, by RIE (reactive ion etching) method. Finally, the same polyamic acid solution is spin-coated over the patterned core layer, as an upper cladding lacer, and is thermally cured, thereby preparing an embedded channel waveguide.

  一种聚酰亚胺光波导，包括一个由聚酰亚胺制成的芯子（2），其折射率可通过电子束辐照控制到预定值；以及一个与芯子接触的包层（1，3），其折射率低于芯子的折射率。 将聚酰胺酸溶液旋涂在硅等基底上，并通过热固化形成聚酰亚胺层。电子束照射聚酰亚胺层的整个表面，使折射率变为预定值。聚酰亚胺层的电子束吸收剂量取决于聚酰亚胺的成分、电子束的能量和电子束辐照的应用量。折射率大致随之变化。 经电子束辐照的聚酰亚胺层被用作核心层。 然后，在芯层上旋涂相同的聚酰胺酸溶液，并进行热固化。材料与基底分离，得到双层结构的聚酰亚胺薄膜。 然后，将双层结构的聚酰亚胺薄膜反转，使辐照聚酰亚胺层位于上表面。反转薄膜的下表面通过热压接合等方法粘附在另一块硅衬底上。 然后，用 RIE（反应离子蚀刻）方法将芯层图案化为所需的形状，例如矩形。 最后，将相同的聚酰胺酸溶液旋涂在图案化的芯层上，作为上覆层，并进行热固化，从而制备出嵌入式通道波导。
• Waveguide device and method for production thereof
  申请人：HOECHST AKTIENGESELLSCHAFT

  公开号：EP0720030A1

  公开（公告）日：1996-07-03

  A waveguide device comprising at least a waveguiding layer, a cladding layer and, optionally, an adhesion-enhancing layer is disclosed. By using specific fluorinated polyimides as materials for each of the layers of the waveguide device, the process for producing the waveguide device is simplified, the production cost is reduced, and the flexibility is imparted to the waveguide device, which are not achieved in a quartz-type waveguide. Also, a single mode, a low loss at 1.3 micron band and a high moisture-resistance which are not achieved by conventional plastic-type waveguide are possible.

  本发明公开了一种波导装置，该装置至少包括一个波导层、一个包层和一个附着力增强层。通过使用特定的氟化聚酰亚胺作为波导器件各层的材料，简化了波导器件的生产工艺，降低了生产成本，并赋予了波导器件石英型波导无法实现的灵活性。此外，还可以实现传统塑料型波导无法实现的单模、1.3 微米波段的低损耗和高防潮性。