4-甲基-3-氰基吡啶氮氧化物 | 7153-67-5

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 中文名称: 4-甲基-3-氰基吡啶氮氧化物
• 英文名称: 3-Cyan-4-methylpyridin-1-oxid
• 英文别名: 4-Methylpyridine-3-carbonitrile 1-oxide；4-methyl-1-oxidopyridin-1-ium-3-carbonitrile
• CAS: 7153-67-5
• 化学式: C₇H₆N₂O
• 分子量: 134.137
• InChiKey: ZOIFVCGYFHRBIO-UHFFFAOYSA-N

物化性质

• 沸点：
  382.1±22.0 °C(Predicted)
• 密度：
  1.11±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  10
• 可旋转键数：
  0
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.14
• 拓扑面积：
  49.2
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  4-甲基-3-氰基吡啶氮氧化物 在 potassium carbonate 作用下， 以 甲醇 、 水 为溶剂， 反应 5.08h， 生成 3-Cyano-4-hydroxymethylpyridin
  参考文献：
  名称：

  Protoberberine ausReissert-Verbindungen, 3. Mitt.: Synthese und Umsetzungsversuche von 8H-Isochino [2,1-b][2,7]naphthyridin-8-on. Protoberberines from Reissert Compounds, III: Synthesis and Attempted Reactions of 8H-Isoquino[2,1-b][2,7]naphthyridin-8-one

  摘要：

  DOI：

  10.1002/ardp.19943270814
• 作为产物：
  描述：

  3-氰基-4-甲基吡啶 在 双氧水 作用下， 以 溶剂黄146 为溶剂， 以81%的产率得到4-甲基-3-氰基吡啶氮氧化物
  参考文献：
  名称：

  Protoberberine ausReissert-Verbindungen, 3. Mitt.: Synthese und Umsetzungsversuche von 8H-Isochino [2,1-b][2,7]naphthyridin-8-on. Protoberberines from Reissert Compounds, III: Synthesis and Attempted Reactions of 8H-Isoquino[2,1-b][2,7]naphthyridin-8-one

  摘要：

  DOI：

  10.1002/ardp.19943270814

文献信息

• Fungicidal composition and method for controlling plant diseases
  申请人：Nishide Hisaya

  公开号：US20060194849A1

  公开（公告）日：2006-08-31

  A fungicidal composition containing, as active ingredients, (a) a benzoylpyridine derivative represented by the following formula or its salt: wherein X is a halogen atom, a nitro group, a substitutable hydrocarbon group, a substitutable alkoxy group, a substitutable aryloxy group, a substitutable cycloalkoxy group, a hydroxyl group, a substitutable alkylthio group, a cyano group, a carboxyl group which may be esterified or amidated, or a substitutable amino group, n is 1, 2, 3 or 4; R 1 is a substitutable alkyl group, R 2′ is a substitutable alkyl group, a substitutable alkoxy group, a substitutable aryloxy group, a substitutable cycloalkoxy group or a hydroxyl group, p is 1, 2 or 3, and R 2″ is a substitutable alkoxy group or a hydroxyl group, provided that at least two of R 2′ and R 2″ optionally form a condensed ring containing an oxygen atom and (b) at least one other fungicide.

  一种杀真菌组合物，包含以下活性成分：（a）一种苯甲酰吡啶衍生物或其盐，其化学式如下：其中X是卤素原子、硝基、可替代的碳氢基团、可替代的烷氧基团、可替代的芳氧基团、可替代的环烷氧基团、羟基、可替代的烷硫基团、氰基、可酯化或酰胺化的羧基或可替代的氨基团，n为1、2、3或4；R1是可替代的烷基团，R2'是可替代的烷基团、可替代的烷氧基团、可替代的芳氧基团、可替代的环烷氧基团或羟基，p为1、2或3，R2"是可替代的烷氧基团或羟基，但R2'和R2"中至少有两个可选地形成含氧原子的螺环；（b）至少一种其他杀真菌剂。
• FUNGICIDAL COMPOSITION AND METHOD FOR CONTROLLING PLANT DISEASES
  申请人：NISHIDE Hisaya

  公开号：US20090247763A1

  公开（公告）日：2009-10-01

  It is to provide a fungicidal composition having stable and high fungicidal effects against cultivated crops infected with plant diseases resulting from plant diseases. A fungicidal composition containing as active ingredients (a) a benzoylpyridine derivative represented by the formula (I) or its salt: (wherein X is a halogen atom, a nitro group, a substitutable hydrocarbon group, a substitutable alkoxy group, a substitutable aryloxy group, a substitutable cycloalkoxy group, a hydroxyl group, a substitutable alkylthio group, a cyano group, a carboxyl group which may be esterified or amidated, or a substitutable amino group, n is 1, 2, 3 or 4; R 1 is a substitutable alkyl group, R 2′ is a substitutable alkyl group, a substitutable alkoxy group, a substitutable aryloxy group, a substitutable cycloalkoxy group or a hydroxyl group, a is 1, 2 or 3, and R 2″ is a substitutable alkoxy group or a hydroxyl group, provided that at least two of R 2′ and R 2″ may form a condensed ring containing an oxygen atom) and (b) at least one another fungicide.

  提供一种杀菌组合物，对由植物疾病引起的种植作物感染的植物疾病具有稳定和高效的杀菌效果。该杀菌组合物包含以下活性成分：(a)一种由式(I)表示的苯甲酰吡啶衍生物或其盐：(其中X为卤素原子、硝基、可替换的碳氢基、可替换的烷氧基、可替换的芳氧基、可替换的环烷氧基、羟基、可替换的烷硫基、氰基、可酯化或酰胺化的羧基或可替换的氨基，n为1、2、3或4；R1为可替换的烷基，R2'为可替换的烷基、可替换的烷氧基、可替换的芳氧基、可替换的环烷氧基或羟基，a为1、2或3，R2''为可替换的烷氧基或羟基，但至少有R2'和R2''中的两个可以形成含氧原子的缩环)和(b)至少另一种杀菌剂。
• Laser marking resin composition
  申请人：JAPAN SYNTHETIC RUBBER CO., LTD.

  公开号：EP0708147A1

  公开（公告）日：1996-04-24

  A laser marking resin composition excellent in appearance of molded article and impact resistance which comprises: (A) 100 parts by weight of a rubber-reinforced vinyl resin consisting of: (A-1) 1 to 100% by weight of a rubber-reinforced resin having a grafting degree of 5 to 150% by weight obtained by polymerizing, in the presence of (a) 5 to 70% by weight of a rubbery polymer, (b) 95 to 30% by weight of at least one monomer selected from the group consisting of an aromatic vinyl compound, a vinyl cyanide compound, a (meth)acrylic acid ester, maleic anhydride and a maleimide compound, provided that (a) + (b) = 100% by weight, and (A-2) 99 to 0% by weight of a polymer obtained by polymerizing at least one monomer selected from the group consisting of an aromatic vinyl compound, a vinyl cyanide compound, a (meth)acrylic acid ester, maleic anhydride and a maleimide compound, provided that (A-1) + (A-2) = 100% by weight, the matrix resin in the component (A) having an intrinsic viscosity [η] of 0.1 to 1.5 dl/g as measured in methyl ethyl ketone at 30°C, and (B) 0.01 to 30 parts by weight of at least one compound selected from the group consisting of (B-1) titanium black, (B-2) black iron oxide, (B-3) yellow iron oxide and (B-4) carbon black.

  一种激光打标树脂组合物，具有优异的成型品外观和抗冲击性，包括 (A) 100 重量份的橡胶增强乙烯基树脂，由以下成分组成 (A-1)1-100%（按重量计）接枝度为 5-150%（按重量计）的橡胶增强树脂，该树脂是在(a)5-70%（按重量计）的橡胶聚合物，(b)95-30%（按重量计）的至少一种单体的存在下聚合而成，该单体选自由芳香族乙烯基化合物、乙烯基氰化物、（甲基）丙烯酸酯、马来酸酐和马来酰亚胺化合物组成的组，条件是(a)+(b)=100%（按重量计），以及 (A-2) 通过聚合至少一种选自芳香族乙烯基化合物、乙烯基氰化物、(甲基)丙烯酸酯、马来酸酐和马来酰亚胺化合物的单体而得到的聚合物，重量百分比为 99-0%、 以重量计，(A-1)+(A-2)=100%，组分(A)中的基体树脂在 30°C 的甲乙酮中的固有粘度[η]为 0.1 至 1.5 dl/g，以及 (B) 0.01 至 30 重量份的至少一种化合物，选自(B-1)钛黑、(B-2)黑氧化铁、 (B-3)黄氧化铁和(B-4)炭黑组成的组。
• Thermoplastic resin composition and shaped articles thereof
  申请人：JSR Corporation

  公开号：EP1223195A2

  公开（公告）日：2002-07-17

  Described are a thermoplastic resin composition containing (A): one or more rubber reinforced thermoplastic resins, (B) : one or more acrylic resins and (C) : one or more thermoplastic norbornene resins, and further containing (D): one or more styrenic resins other than (A) and (E) : coloring agents as needed, and a shaped article obtained by forming the composition. Described thermoplastic resin composition is excellent in heat resistance, strength and processability, and excellent in laser marking properties, so that it is useful for various applications.

  所述热塑性树脂组合物含有(A)：一种或多种橡胶增强热塑性树脂、(B)：一种或多种丙烯酸树脂和(C)：一种或多种热塑性降冰片烯树脂，并进一步含有(D)：除(A)和(E)以外的一种或多种苯乙烯树脂：所需的着色剂，以及通过形成该组合物而获得的成型品。所述热塑性树脂组合物具有优异的耐热性、强度和可加工性，并具有优异的激光打标性能，因此可用于各种用途。
• Preparation of fungicidal benzoylpyridine derivatives
  申请人：ISHIHARA SANGYO KAISHA, LTD.

  公开号：EP2338335A1

  公开（公告）日：2011-06-29

  A process for producing a benzoylpyridine derivative represented by the following formula (I) or its salt: (wherein X is a halogen atom, a nitro group, a substitutable hydrocarbon group, a substitutable alkoxy group, a substitutable aryloxy group, a substitutable cycloalkoxy group, a hydroxyl group, a substitutable alkylthio group, a cyano group, a carboxyl group which may be esterified or amidated, or a substitutable amino group; n is 1, 2, 3 or 4; R' is a substitutable alkyl group; R2' is a substitutable alkyl group, a substitutable alkoxy group, a substitutable aryloxy group, a substitutable cycloalkoxy group or a hydroxyl group; p is 1, 2 or 3; and R2" is a substitutable alkoxy group or a hydroxyl group; wherein at least two of R2' and R2" may form a condensed ring containing an oxygen atom); characterized by reacting a compound represented by the formula (XIII): (wherein X and n are as defined above) with a compound represented by the formula (XIV): (wherein R1, R2', R2" and p are as defined above) in the presence of a Lewis acid or a dehydrating agent.

  一种生产下式 (I) 所代表的苯甲酰吡啶衍生物或其盐的工艺： (其中 X 是卤原子、硝基、可被取代的烃基、可被取代的烷氧基、可被取代的芳氧基、可被取代的环烷氧基、羟基、可被取代的烷硫基、氰基、可被酯化或酰胺化的羧基或可被取代的氨基；n 是 1、2、3 或 4；R'是可被取代的烷基；R2'是可被取代的烷基、可被取代的烷氧基、可被取代的芳氧基、可被取代的环烷氧基或羟基；p 是 1、2 或 3；R2 "是可被取代的烷氧基或羟基；其中至少两个 R2'和 R2 "可形成含有一个氧原子的缩合环）； 其特征是使式 (XIII) 所代表的化合物发生反应： 式(XIII)代表的化合物(其中X和n如上定义)与式(XIV)代表的化合物反应： (其中 R1、R2'、R2 "和 p 如上定义）的化合物在路易斯酸或脱水剂存在下反应。