2-[3-(Bromomethyl)-5-pyridin-2-ylphenyl]pyridine | 249928-03-8

• 分子结构分类: 有机化合物 - 有机杂环化合物 - 吡啶及其衍生物
• 英文名称: 2-[3-(Bromomethyl)-5-pyridin-2-ylphenyl]pyridine
• 英文别名: 2-[3-(bromomethyl)-5-pyridin-2-ylphenyl]pyridine
• CAS: 249928-03-8
• 化学式: C₁₇H₁₃BrN₂
• 分子量: 325.208
• InChiKey: RLMMSPQMJVOZLT-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.7
• 重原子数：
  20
• 可旋转键数：
  3
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.06
• 拓扑面积：
  25.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  permethylated mono-6-hydroxy-β-cyclodextrin 、 2-[3-(Bromomethyl)-5-pyridin-2-ylphenyl]pyridine 在 sodium hydride 作用下， 以 乙醚 为溶剂， 以33%的产率得到
  参考文献：
  名称：

  An efficient synthesis of versatile terpyridine analogues for cyclometallated luminescent cyclodextrins

  摘要：

  An efficient synthetic method for preparing functionalised terpyridyl analogues based on Negishi's zinc coupling is developed. These ligands form cyclometallated complexes; attaching them to cyclodextrins allows preparation of luminescent cyclometallated ruthenium cyclodextrins for the assembly of photoactive units via non-covalent interactions, (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)01386-6
• 作为产物：
  描述：

  5-methyl-1,3-di-(2'-pyridyl)benzene 在 N-溴代丁二酰亚胺(NBS) 、 过氧化苯甲酰 作用下， 以 四氯化碳 为溶剂， 以64%的产率得到2-[3-(Bromomethyl)-5-pyridin-2-ylphenyl]pyridine
  参考文献：
  名称：

  An efficient synthesis of versatile terpyridine analogues for cyclometallated luminescent cyclodextrins

  摘要：

  An efficient synthetic method for preparing functionalised terpyridyl analogues based on Negishi's zinc coupling is developed. These ligands form cyclometallated complexes; attaching them to cyclodextrins allows preparation of luminescent cyclometallated ruthenium cyclodextrins for the assembly of photoactive units via non-covalent interactions, (C) 1999 Elsevier Science Ltd. All rights reserved.

  DOI：

  10.1016/s0040-4039(99)01386-6

文献信息

• An efficient synthesis of versatile terpyridine analogues for cyclometallated luminescent cyclodextrins
  作者：Murielle Chavarot、Zoe Pikramenou

  DOI：10.1016/s0040-4039(99)01386-6

  日期：1999.9

  An efficient synthetic method for preparing functionalised terpyridyl analogues based on Negishi's zinc coupling is developed. These ligands form cyclometallated complexes; attaching them to cyclodextrins allows preparation of luminescent cyclometallated ruthenium cyclodextrins for the assembly of photoactive units via non-covalent interactions, (C) 1999 Elsevier Science Ltd. All rights reserved.