benzene-1,3,5-tricarboxylic acid tris-n-propylamide | 152422-63-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: benzene-1,3,5-tricarboxylic acid tris-n-propylamide
• 英文别名: 1,3,5-Benzenetricarboxylic acid tris(n-propylamide)；1-N,3-N,5-N-tripropylbenzene-1,3,5-tricarboxamide
• CAS: 152422-63-4
• 化学式: C₁₈H₂₇N₃O₃
• 分子量: 333.431
• InChiKey: MFBYQNCARGDHEM-UHFFFAOYSA-N

物化性质

• 熔点：
  289 °C
• 沸点：
  567.2±45.0 °C(Predicted)
• 密度：
  1.077±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.4
• 重原子数：
  24
• 可旋转键数：
  9
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.5
• 拓扑面积：
  87.3
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  benzene-1,3,5-tricarboxylic acid tris-n-propylamide 在 氯化亚砜 作用下， 反应 2.0h， 生成 N¹,N³,N⁵-Tripropyl-benzimidoyl chloride
  参考文献：
  名称：

  低聚胺的血小板聚集抑制和抗凝作用，XXII：双恶唑-、双咪唑-、双噻唑-和低聚-1,2,4-噻二唑亚胺

  摘要：

  一个介离子4,4'-丙烯-双-恶唑-5-亚胺（5），两个2,2'-间-亚苯基-双-咪唑-4-亚胺（9a，b），五个4,4'-苯-双-（和三）-噻唑-2-胺（13a、b、14a-c）和 14 3,3'-苯-双-（和三）-1,2,4-噻二唑亚胺（18a-o）合成并测定了它们的抗血小板和抗凝活性。最有效的化合物是三噻二唑衍生物 18m，它在 10 μmol/L 的浓度下抑制了 50% 的胶原蛋白诱导的血小板聚集（Born 试验）。在高达 400 μmol/L 时未观察到抗凝作用（快速测试）。在噻唑胺系列中可以看到抗血小板和抗凝活性的结合。

  DOI：

  10.1002/ardp.19933260706
• 作为产物：
  描述：

  正丙胺 、 tris(salicyl) trimesate 在 sodium chloride 作用下， 以 二甲基亚砜 为溶剂， 生成 benzene-1,3,5-tricarboxylic acid tris-n-propylamide
  参考文献：
  名称：

  Mechanism of Site-Directed Protein Cross-Linking. Protein-Directed Selectivity in Reactions of Hemoglobin with Aryl Trimesates

  摘要：

  Site-directed cross-linking of hemoglobin has become an efficient way to produce a structurally defined altered protein with desirable functional properties. The reagent trimesoyl tris(3,5-dibromosalicylate) (1) introduces a bis amide cross-link derived from the epsilon-amino groups of the side chains of the two beta-Lys-82 residues in human hemoglobin. The basis of its specificity was investigated using a set of analogues of 1 (2-12). There are marked differences in the reaction patterns of these compounds with amino groups in hemoglobin compared to reactions with n-propylamine. The compounds that effectively modify the protein contain a carboxyl group ortho to the phenolic oxygen of the ester, while materials with meta or para carboxyl groups give little or no reaction. In contrast, the reactions with n-propylamine are slowest with the ortho carboxyl materials. Addition of the unreactive compound 5 to a solution containing hemoglobin reduces the ability of 1 to modify the protein, showing that the unreactive compound binds but does not react. On the basis of these observations and the known reaction patterns of salicylates, it is clear that: the environment in the protein controls the reaction, regardless of the inherent reactivity of the reagent. We propose that the carboxyl group positions the reagent critically within the protein. Only the ortho arrangement permits transfer of the acyl function to the nucleophile.

  DOI：

  10.1021/jo991514n

文献信息

• CURABLE COMPOSITION, CURED PRODUCT, COLOR FILTER, METHOD FOR PRODUCING COLOR FILTER, SOLID-STATE IMAGING ELEMENT, AND IMAGE DISPLAY DEVICE
  申请人：FUJIFILM Corporation

  公开号：US20200385582A1

  公开（公告）日：2020-12-10

  Provided are a curable composition including a compound represented by Formula 1 and having a maximum absorption wavelength in a range of 600 nm or more and less than 700 nm, or a polymer having a structure represented by Formula 2 and having a maximum absorption wavelength in a range of 600 nm or more and less than 700 nm; a polymerizable compound; and a chromatic colorant different from the compound represented by Formula 1 and the polymer represented by Formula 2, as well as a cured product of the curable composition; a color filter including the cured product; a method for producing a color filter; a solid-state imaging element; and an image display device.

  提供一种可治愈的组合物，包括由式1表示的化合物，其最大吸收波长在600纳米或更大且小于700纳米范围内，或者具有由式2表示的结构的聚合物，其最大吸收波长在600纳米或更大且小于700纳米范围内；一种可聚合的化合物；和一种与式1表示的化合物和式2表示的聚合物不同的色素染料，以及所述可治愈组合物的固化产物；包括所述固化产物的彩色滤光片；生产彩色滤光片的方法；固态成像元件；和图像显示装置。
• Remarkable Viscoelasticity of Organic Solvents Containing Trialkyl-1,3,5-benzenetricarboxamides and Their Intermolecular Hydrogen Bonding
  作者：Kenji Hanabusa、Chiemi Koto、Mutsumi Kimura、Hirofusa Shirai、Akikazu Kakehi

  DOI：10.1246/cl.1997.429

  日期：1997.5

  Remarkable rise of viscosity was observed by adding trialkyl-1,3,5-benzenetricarboxamide into organic solvents; the formation of highly viscoelastic solution was discussed by viscosity measurement, FTIR spectroscopy, and X-ray molecular structure in the crystal.

  在有机溶剂中加入三烷基-1,3,5-苯三甲酰胺后，观察到粘度显著上升；通过粘度测量、傅里叶变换红外光谱和晶体中的 X 射线分子结构，讨论了高粘弹性溶液的形成。
• Coloring composition, cured film, color filter, method for manufacturing color filter, solid-state imaging device, image display device, organic electroluminescent element, colorant, and method for producing colorant
  申请人：FUJIFILM Corporation

  公开号：US10317794B2

  公开（公告）日：2019-06-11

  A coloring composition having excellent light fastness, color migration properties, and flatness, a colorant, and a method for producing a colorant are provided. Further, a cured film, a color filter, a method for manufacturing a color filter, a solid-state imaging device, an image display device, and an organic electroluminescent element, each using such the coloring composition, are also provided. The coloring composition contains a colorant represented by General Formula (1) and a curable compound, and has a specific absorbance of 5 or more at a maximum absorption wavelength of 400 nm to 800 nm. R1 represents an (m+n)-valent linking group, P represents a monovalent substituent having a repeating units derived from a vinyl compound, D represents a colorant structure, and R2 and L1 each independently represent a single bond or a divalent linking group. (D-R2)n—R1-(L1-P)m  (1)

  本发明提供了一种具有优异耐光性、色彩迁移特性和平整度的着色组合物、着色剂以及生产着色剂的方法。此外，还提供了一种固化薄膜、一种彩色滤光片、一种制造彩色滤光片的方法、一种固态成像装置、一种图像显示装置和一种有机电致发光元件，它们都使用了这种着色组合物。着色组合物含有通式（1）表示的着色剂和可固化化合物，在最大吸收波长 400 纳米至 800 纳米处的比吸收率为 5 或以上。R1 代表(m+n)价连接基团，P 代表具有来自乙烯基化合物的重复单元的单价取代基，D 代表着色剂结构，R2 和 L1 各自独立地代表单键或二价连接基团。 (D-R2)n-R1-(L1-P)m (1)
• Solution casting method and polymer film
  申请人：Sugiura Masaru

  公开号：US20050077648A1

  公开（公告）日：2005-04-14

  A solvent in which dichloromethane is mixed with alcohol as a poor solvent is used for preparing a dope. Alcohol is supplied to the dope in a inline pipe to mix with a static mixer, such as a casting dope in which a composition of alcohol is increased. The temperature of the rotary drum is adjusted to −7° C. The casting dope is fed from a casting die to the rotary drum so as to form a casting film whose thickness is 40 μm. Since the content of alcohol is high and a storage modulus of the cooled casting film is at least 150 thousands Pa, the peeling defect does not occur, and the stretch is reduced as far as possible. A gel-like film is dried by a tenter type drying device, and stretched such that the stretch ratio is at most 110%. The produced film is thin and excellent in a surface condition and optical isotropy.

  二氯甲烷与作为劣质溶剂的酒精混合的溶剂用于制备涂料。酒精通过内联管道供应到涂料中，与静态混合器混合，如增加酒精成分的铸造涂料。将浇注料从浇注模具送入旋转滚筒，以形成厚度为 40 μm 的浇注膜。由于酒精含量高，冷却后的浇注膜的储存模量至少为 15 万帕，因此不会出现剥离缺陷，拉伸也尽可能减小。凝胶状薄膜由拉幅机干燥，拉伸率不超过 110%。生产出的薄膜很薄，表面状态和光学各向同性都很好。
• Electret materials
  申请人：Chin Hui

  公开号：US20080249269A1

  公开（公告）日：2008-10-09

  Disclosed are electret materials with outstanding thermal and charge stability. The electret materials comprise a melt blend of a thermoplastic polymer and one or more compounds selected from the aromatic trisamides. The aromatic trisamides are for example of the formula The melt blends are subjected to an electret treatment, for example a corona treatment. The electret materials are for example nonwoven polyolefin webs and are employed as filter materials, wipes, absorbent materials, filter masks, acoustic materials, printing substrates, measuring devices or contactless switches. The present electret materials may also comprise a further additive selected from the hindered amine light stabilizers and the hydroxyphenylalkylphosphonic esters or monoesters.