(2E,4E)-6-羟基己-2,4-二烯醛 | 141812-70-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 中文名称: (2E,4E)-6-羟基己-2,4-二烯醛
• 英文名称: 6-Hydroxy-trans,trans-2,4-hexadienal
• 英文别名: (2E,4E)-6-hydroxyhexanedienal；(2E,4E)-6-hydroxyhexadienal；(2E,4E)-6-hydroxyhexa-2,4-dienal
• CAS: 141812-70-6
• 化学式: C₆H₈O₂
• 分子量: 112.128
• InChiKey: PCYZGEHNECVSCF-ZPUQHVIOSA-N

物化性质

• 沸点：
  150.05°C (rough estimate)
• 密度：
  1.0299 (rough estimate)

计算性质

• 辛醇/水分配系数(LogP)：
  -0.1
• 重原子数：
  8
• 可旋转键数：
  3
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.17
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为产物：
  描述：

  (2E,4E)-6-acetoxy-2,4-hexadienal 在 氢氧化钾 作用下， 以 1,4-二氧六环 为溶剂， 反应 2.0h， 生成 (2E,4E)-6-羟基己-2,4-二烯醛
  参考文献：
  名称：

  来自 Hypochoeris radicata 的抗微生物应激化合物

  摘要：

  用氯化铜加压的 Hypochoeris radicata 叶子的渗出液提供了两种eudesmane 和愈创木酚型倍半萜烯，以及两种链烯醛，(2E,4E)-6-羟基己二烯醛和(2E,4E)-己二烯醛（粘二醛）。它们的结构是通过光谱和合成方法确定的。

  DOI：

  10.1016/0031-9422(94)00792-r

文献信息

• Indium-Promoted Barbier-Type Allylations in Aqueous Media: New Access to 2-C- and 4-C-Branched Sugars
  作者：André Lubineau、Yves Canac、Nicole Le??Goff

  DOI：10.1002/1615-4169(200206)344:3/4<319::aid-adsc319>3.0.co;2-s

  日期：2002.6

  Indium-promoted Barbier-type allylations in aqueous media of 2-bromo-4-enopyranoside (3) and 4-bromo-2-enopyranosides (2β, 6α and 6β) provide a new access to different 2-C-branched sugars (7, 11, 13) and 4-C-branched sugar (18). Moreover, apart from the synthesis and characterization of these C-branched sugars, mechanistic aspects of these reactions are discussed.

  在 2-bromo-4-enopyranoside (3) 和 4-bromo-2-enopyranosides（2β、6α 和 6β）的水性介质中，铟促进的 Barbier 型烯丙基化为不同的 2-C-支链糖提供了新途径（7 , 11, 13) 和 4-C-支链糖 (18)。此外，除了这些 C 支糖的合成和表征之外，还讨论了这些反应的机理方面。
• BIOMARKERS FOR MALARIA DIAGNOSIS
  申请人：The United States of America, as represented by the Secretary, Dept. of Health and Human Services

  公开号：US20180052161A1

  公开（公告）日：2018-02-22

  Disclosed herein are methods of detecting Plasmodium in a subject (for example, presence of Plasmodium parasite) by detecting the presence and/or amount of one or more metabolites in a sample from the subject. In some embodiments, the methods include detecting in the sample one or more metabolites listed in Table 1, Table 2, and/or Tables 5-8. The amount of the one or more metabolites in the sample is compared to the amount of the one or more metabolites in a control and presence of Plasmodium is determined if the amount of the one or more metabolites is different (for example statistically significantly increased or decreased) compared to the control.
• [EN] BIOMARKERS FOR MALARIA DIAGNOSIS<br/>[FR] BIOMARQUEURS POUR LE DIAGNOSTIC DU PALUDISME
  申请人：THE US SECRETARY DEPT OF HEALTH & HUMAN SERVICES

  公开号：WO2016149386A1

  公开（公告）日：2016-09-22

  Disclosed herein are methods of detecting Plasmodium in a subject (for example, presence of Plasmodium parasite) by detecting the presence and/or amount of one or more metabolites in a sample from the subject. In some embodiments, the methods include detecting in the sample one or more metabolites listed in Table 1, Table 2, and/or Tables 5-8. The amount of the one or more metabolites in the sample is compared to the amount of the one or more metabolites in a control and presence of Plasmodium is determined if the amount of the one or more metabolites is different (for example statistically significantly increased or decreased) compared to the control.
• Antimicrobial stress compounds from Hypochoeris radicata
  作者：Y Maruta

  DOI：10.1016/0031-9422(94)00792-r

  日期：1995.3

  The exudates of Hypochoeris radicata leaves stressed with cupric chloride afforded two eudesmane- and guaiane-type sesquiterpenes, and two alkenals, (2E,4E)-6-hydroxyhexadienal and (2E,4E)-hexadienedial (mucondialdehyde). Their structures were determined by spectroscopic and synthetic methods.

  用氯化铜加压的 Hypochoeris radicata 叶子的渗出液提供了两种eudesmane 和愈创木酚型倍半萜烯，以及两种链烯醛，(2E,4E)-6-羟基己二烯醛和(2E,4E)-己二烯醛（粘二醛）。它们的结构是通过光谱和合成方法确定的。