Trimethyl-(2-methylidene-5-phenylpentyl)silane | 880767-73-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Trimethyl-(2-methylidene-5-phenylpentyl)silane
• 英文别名: trimethyl-(2-methylidene-5-phenylpentyl)silane
• CAS: 880767-73-7
• 化学式: C₁₅H₂₄Si
• 分子量: 232.441
• InChiKey: BUXZBWYJUXSEPN-UHFFFAOYSA-N

物化性质

• 沸点：
  303.4±21.0 °C(Predicted)
• 密度：
  0.865±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.47
• 拓扑面积：
  0
• 氢给体数：
  0
• 氢受体数：
  0

反应信息

• 作为反应物：
  描述：

  Trimethyl-(2-methylidene-5-phenylpentyl)silane 、 苯甲醛二甲缩醛 在 三氟化硼乙醚 作用下， 以 二氯甲烷 为溶剂， 反应 0.5h， 以75%的产率得到(1-Methoxy-3-methylidene-6-phenylhexyl)benzene
  参考文献：
  名称：

  Preparation of 2-trimethylsilylmethyl-1-alkene; cross-coupling and protodesilylation sequence from 1,1-dibromo-1-alkene

  摘要：

  A new method for the preparation of exomethylene type allylsilane is described. Selective mono-protodesilylation of 1-trimethylsityl-2-trimethylsilylmethyl-2-alkenes 2 with PPTS afforded 2-trimethylsilylmethyl-l-alkeiles 4 in excellent yields. Since the resulting allylsilanes 4 possess an exomethylene unit, the reactions of 4 with carbonyl compounds in the presence of Lewis acids gave the corresponding product 7 having an exomethylene unit in excellent yields. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.12.044
• 作为产物：
  描述：

  4-phenyl-1,1-dibromo-1-butene 在 palladium diacetate 、 溶剂黄146 、 三苯基膦 作用下， 以 四氢呋喃 、 乙醚 、 水 为溶剂， 反应 2.5h， 生成 Trimethyl-(2-methylidene-5-phenylpentyl)silane
  参考文献：
  名称：

  Preparation of 2-trimethylsilylmethyl-1-alkene; cross-coupling and protodesilylation sequence from 1,1-dibromo-1-alkene

  摘要：

  A new method for the preparation of exomethylene type allylsilane is described. Selective mono-protodesilylation of 1-trimethylsityl-2-trimethylsilylmethyl-2-alkenes 2 with PPTS afforded 2-trimethylsilylmethyl-l-alkeiles 4 in excellent yields. Since the resulting allylsilanes 4 possess an exomethylene unit, the reactions of 4 with carbonyl compounds in the presence of Lewis acids gave the corresponding product 7 having an exomethylene unit in excellent yields. (c) 2007 Elsevier Ltd. All rights reserved.

  DOI：

  10.1016/j.tetlet.2006.12.044

文献信息

• Reactions of 1,1-Bis(silylmethyl)-1-alkene with N-Halosuccinimide and Ozone
  作者：Jun'ichi Uenishi、Yusuke Tanaka、Masashi Ohmi、Hotsumi Shimomura、Nobuyuki Kawai

  DOI：10.3987/com-05-s(k)37

  日期：——

  Electrophilic reactions of 3-phenyl-1,1-bis(trimethylsilymethyl)-1-propene (1) and 1,1-bis[dimethyl(phenyl)silylmethyl]-3-phenyl-1-propene (4) are described. Protodesilylation of 1 with PPTS gave 2-substituted allylsilane (2) in excellent yield. Halogenation of 4 with N-halosuccimide gave a mixture of 3-halo-5-phenyl-2-silylmethyl-l-pentene (5) and 3-halo-5-phenyl-1,2bis(silylmethyl)-1-pentene (6). The reaction of 1 and 4 with ozone gave no carbonyl compounds but gave 3-hydoxy-5-phenyl-2-silylmethyl-1-pentene (7).