(1S)-4-amino-N-(5-amino-1-hydroxymethyl-pentyl)-N-isobutyl-benzenesulfonamide | 449806-99-9

分子结构分类

有机化合物 - 苯类化合物 - 苯和取代衍生物

中文名称

——

中文别名

——

英文名称

(1S)-4-amino-N-(5-amino-1-hydroxymethyl-pentyl)-N-isobutyl-benzenesulfonamide

英文别名

4-amino-N-[(2S)-6-amino-1-hydroxyhexan-2-yl]-N-(2-methylpropyl)benzenesulfonamide

(1S)-4-amino-N-(5-amino-1-hydroxymethyl-pentyl)-N-isobutyl-benzenesulfonamide化学式

CAS

449806-99-9

化学式

C₁₆H₂₉N₃O₃S

mdl

——

分子量

343.491

InChiKey

LIHBMIHZHSLGMC-HNNXBMFYSA-N

BEILSTEIN

——

EINECS

——

物化性质

沸点：

533.8±60.0 °C(Predicted)
密度：

1.179±0.06 g/cm3(Predicted)

计算性质

辛醇/水分配系数(LogP)：

1.2
重原子数：

23
可旋转键数：

10
环数：

1.0
sp3杂化的碳原子比例：

0.62
拓扑面积：

118
氢给体数：

3
氢受体数：

6

SDS

SDS：26e82628041ce0071296d4a11f34e504

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上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	Nα-(4-aminobenzenesulfonyl)-Nα-isobutyl-L-lysine	652985-62-1	C₁₆H₂₇N₃O₄S	357.474
——	(1-S)-{4-[(5-tert-butoxycarbonylamino-1-hydroxymethyl-pentyl)-isobutyl-sulfamoyl]-phenyl}-carbamic acid tert-butyl ester	900187-22-6	C₂₆H₄₅N₃O₇S	543.725
——	Nα-(4-aminobenzenesulfonyl)-Nα-isobutyl-L-lysine methyl ester	449806-88-6	C₁₇H₂₉N₃O₄S	371.501
——	Nα-isobutyl-Nα-(4-acetamidobenzenesulfonyl)-L-α-ε-amino-caprolactam	449806-97-7	C₁₈H₂₇N₃O₄S	381.496

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	methyl N-[(1S)-2-[[(5S)-5-[(4-aminophenyl)sulfonyl-isobutyl-amino]-6-hydroxy-hexyl]amino]-1-benzyl-2-oxo-ethyl]carbamate	——	C₂₇H₄₀N₄O₆S	548.704
——	(1S,5S)-(1-{5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2-naphthalen-2-yl-ethyl)-carbamic Acid Methyl Ester	——	C₃₁H₄₂N₄O₆S	598.764
——	Carbamic acid, [(1S)-2-[[(5S)-5-[[(4-aminophenyl)sulfonyl](2-methylpropyl)amino]-6-hydroxyhexyl]amino]-1-(1-naphthalenylmethyl)-2-oxoethyl]-, methyl ester	——	C₃₁H₄₂N₄O₆S	598.764
——	(1S,5S)-{1-(5-[(4-amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl)-2-naphthalen-2-yl-ethyl}-carbamic acid tert-butyl ester	612548-19-3	C₃₄H₄₈N₄O₆S	640.844
——	(2S)-2-Acetylamino-N-{(5S)-5-[(4-amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexyl}-3,3-diphenyl-propionamide	——	C₃₃H₄₄N₄O₅S	608.802
——	Bes(4-NH2)-N(iBu)Lys(Fmoc)(Fmoc)-ol	500221-64-7	C₃₁H₃₉N₃O₅S	565.734
——	N-[(1S)-1-[[(5S)-5-[(4-aminophenyl)sulfonyl-isobutyl-amino]-6-hydroxy-hexyl]carbamoyl]-2,2-diphenyl-ethyl]cyclopropanecarboxamide	——	C₃₅H₄₆N₄O₅S	634.84
——	N-[(1S)-2-[[(5S)-5-[(4-aminophenyl)sulfonyl-isobutyl-amino]-6-hydroxy-hexyl]amino]-1-(1-naphthylmethyl)-2-oxo-ethyl]morpholine-4-carboxamide	——	C₃₄H₄₇N₅O₆S	653.8
N-[(1s)-1-[[[(5s)-5-[[(4-氨基苯基)磺酰基](2-甲基丙基)氨基]-6-羟基己基]氨基]羰基]-2,2-二苯基乙基]氨基甲酸甲酯	(1S,5S)-(1-{5-[(4-amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-carbamic acid methyl ester	612547-11-2	C₃₃H₄₄N₄O₆S	624.802
——	(2S)-N-[(5S)-5-[(4-aminophenyl)sulfonyl-isobutyl-amino]-6-hydroxy-hexyl]-2-(dimethylcarbamoylamino)-3,3-diphenyl-propanamide	——	C₃₄H₄₇N₅O₅S	637.844
——	N-[(1S)-1-[[(5S)-5-[(4-aminophenyl)sulfonyl-isobutyl-amino]-6-hydroxy-hexyl]carbamoyl]-2,2-diphenyl-ethyl]cyclohexanecarboxamide	——	C₃₈H₅₂N₄O₅S	676.921
——	methyl N-[(1S)-2-[[(5S)-5-[(4-aminophenyl)sulfonyl-isobutyl-amino]-6-hydroxy-hexyl]amino]-2-oxo-1-[(2-phenylphenyl)methyl]ethyl]carbamate	——	C₃₃H₄₄N₄O₆S	624.802
——	(1S,5S)-N-(1-{5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-isonicotinamide	——	C₃₇H₄₅N₅O₅S	671.861
——	(2S)-N-[(5S)-5-[(4-aminophenyl)sulfonyl-isobutyl-amino]-6-hydroxy-hexyl]-3,3-diphenyl-2-[[2-(3-pyridyl)acetyl]amino]propanamide	——	C₃₈H₄₇N₅O₅S	685.888
——	N-[(1S)-1-[[(5S)-5-[(4-aminophenyl)sulfonyl-isobutyl-amino]-6-hydroxy-hexyl]carbamoyl]-2,2-diphenyl-ethyl]morpholine-4-carboxamide	612547-17-8	C₃₆H₄₉N₅O₆S	679.881
——	((1S)-1-{(5S)-5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-carbamic acid pyridin-4-ylmethyl ester	——	C₃₈H₄₇N₅O₆S	701.887
——	N-((1S)-1-{(5S)-5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-4-hydroxy-benzamide	——	C₃₈H₄₆N₄O₆S	686.872
——	N-((1S)-1-{(5S)-5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-3-hydroxy-benzamide	——	C₃₈H₄₆N₄O₆S	686.872
——	(1S,5S)-N-(1-{5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-nicotinamide	——	C₃₇H₄₅N₅O₅S	671.861
——	((1S)-1-{(5S)-5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-carbamic acid pyridin-3-ylmethyl ester	——	C₃₈H₄₇N₅O₆S	701.887
——	N-((1S)-1-{(5S)-5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-2-hydroxy-benzamide	——	C₃₈H₄₆N₄O₆S	686.872
——	((1S)-1-{(5S)-5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-carbamic acid pyridin-2-ylmethyl ester	——	C₃₈H₄₇N₅O₆S	701.887
——	N-[(1S)-1-[[(5S)-5-[(4-aminophenyl)sulfonyl-isobutyl-amino]-6-hydroxy-hexyl]carbamoyl]-2,2-diphenyl-ethyl]-1H-pyrrole-2-carboxamide	——	C₃₆H₄₅N₅O₅S	659.85
——	N-[(1S)-1-[[(5S)-5-[(4-aminophenyl)sulfonyl-isobutyl-amino]-6-hydroxy-hexyl]carbamoyl]-2,2-diphenyl-ethyl]pyrazine-2-carboxamide	——	C₃₆H₄₄N₆O₅S	672.849
——	N-[(1S)-1-[[(5S)-5-[(4-aminophenyl)sulfonyl-isobutyl-amino]-6-hydroxy-hexyl]carbamoyl]-2,2-diphenyl-ethyl]pyridine-2-carboxamide	——	C₃₇H₄₅N₅O₅S	671.861
——	N-((1S)-1-{(5S)-5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-6-methyl-nicotinamide	——	C₃₈H₄₇N₅O₅S	685.888
——	N-(1-{5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-6-hydroxy-nicotinamide	——	C₃₇H₄₅N₅O₆S	687.86
——	6-Amino-N-(1-{5-[(4-amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-nicotinamide	——	C₃₇H₄₆N₆O₅S	686.875
——	N-((1S)-1-{(5S)-5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-4-hydroxy-3-methoxy-benzamide	——	C₃₉H₄₈N₄O₇S	716.899
——	N-((1S)-1-{(5S)-5-[(4-Amino-benzenesulfonyl)-isobutyl-amino]-6-hydroxy-hexylcarbamoyl}-2,2-diphenyl-ethyl)-2-methyl-nicotinamide	——	C₃₈H₄₇N₅O₅S	685.888

反应信息

作为反应物：

描述：

N-甲氧羰基-L-苯基甘氨酸