2,2-Diethyl-bernsteinsaeure-1-methylester | 90647-78-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2,2-Diethyl-bernsteinsaeure-1-methylester
• 英文别名: 3-Ethyl-3-methoxycarbonylpentanoic acid
• CAS: 90647-78-2
• 化学式: C₉H₁₆O₄
• 分子量: 188.224
• InChiKey: KDRJGJOSRASMJK-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.2
• 重原子数：
  13
• 可旋转键数：
  6
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.78
• 拓扑面积：
  63.6
• 氢给体数：
  1
• 氢受体数：
  4

反应信息

• 作为产物：
  描述：

  2,2-二乙基琥珀酸 在 sodium hydroxide 、 硫酸 作用下， 以 乙醇 为溶剂， 生成 2,2-Diethyl-bernsteinsaeure-1-methylester
  参考文献：
  名称：

  Le Moal,H. et al., Bulletin de la Societe Chimique de France, 1964, p. 828 - 830

  摘要：

  DOI：

文献信息

• Diacylglycerol Acyltransferase Inhibitors
  申请人：Bolin David Robert

  公开号：US20090093497A1

  公开（公告）日：2009-04-09

  Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of diseases such as, for example, obesity, type II diabetes mellitus and metabolic syndrome.

  本文提供的是公式(I)的化合物，以及其药物可接受的盐，其中取代基如规范中所述。这些化合物和含有它们的药物组合物对于治疗疾病，例如肥胖症、2型糖尿病和代谢综合征是有用的。
• Low-crystalline propylene random copolymer composition, process for production thereof, and composite laminated polypropylene structure
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0263718A2

  公开（公告）日：1988-04-13

  A novel low-crystalline propylene random copolymer composition comprising [I] 60 to 95 % by weight of a propylene random copolymer and [II] 5 to 40 % by weight of a low-crystalline propylene random copolymer which has excellent heat-sealability, heat-seal imparting property, transparency and antiblocking property and containing a reduced amount of a hydrocarbon-soluble component, a process for production thereof, and polypropylene composite laminated structure having improved heat-sealability and heat seal strength at low temperatures.

  一种新型低结晶丙烯无规共聚物组合物，包括 [60% 至 95% （重量百分比）的丙烯无规共聚物和 [II] 5%至 40%（重量百分比）的低结晶丙烯无规共聚物 具有优异的热封性能、热封性能、透明度和抗阻塞性能，并含有较少量的烃溶性成分的聚丙烯无规共聚物组合物及其生产工艺，以及在低温下具有更好的热封性能和热封强度的聚丙烯复合层压结构。
• Olefin polymerization catalyst component, process for production thereof, olefin polymerization, catalyst, and process for polymerizing olefins
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0360491A2

  公开（公告）日：1990-03-28

  A catalyst component (X˝) obtained by treating an olefin polymerization catalyst (X) formed from (A) a solid titanium catalyst component comprising magnesium, titanium, halogen and an electron donor as essential ingredients, (B) an organoaluminum compound catalyst component, and as required, (C) an electron donor with an alpha-olefin by preliminarily polymerizing the alpha-­olefin in an amount of 0.1 to 500 g per gram of the solid titanium catalyst component (A) in the presence of said catalyst (X), and contacting the treated catalyst (X′) with at least 0.1 mole, per gram-atom of titanium in the treated catalyst (X′), of oxygen. A process for produc­ing the olefin polymerization catalyst component. A catalyst (Y) for olefin polymerization formed from [I] the above catalyst component (X˝), [II] an organoaluminum compound catalyst component and as required [III] an electron donor. Also provided is a process for polymer­izing olefins in the presence of the olefin polymerization catalyst (Y).

  一种催化剂组分(X˝)，它是由(A)一种固体钛催化剂组分(由镁、钛、卤素和电子供体作为基本成分)，(B)一种有机铝化合物催化剂组分，以及根据需要(C)一种电子供体与α-烯烃初步聚合而得到的烯烃聚合催化剂(X)。1至500克每克固体钛催化剂组分(A)在所述催化剂(X)存在下进行聚合，并使处理后的催化剂(X′)与至少0.1摩尔(处理后的催化剂(X′)中每克钛原子)的氧气接触。一种生产烯烃聚合催化剂组分的工艺。由[I]上述催化剂组分(X˝)、[II]有机铝化合物催化剂组分和根据需要[III]电子供体形成的烯烃聚合催化剂(Y)。还提供了一种在烯烃聚合催化剂（Y）存在下聚合烯烃的工艺。
• Olefin polymerization catalyst, component thereof and process for polymerizing olefins with the catalyst, the film and injection-molded article from the obtained polyolefin
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0360497A2

  公开（公告）日：1990-03-28

  An olefin polymerization catalyst component subjected to successive preliminary polymerization treat­ment using each of a straight chain alpha-olefin having 2 to 5 carbon atoms and 3-methyl-1-butene; an olefin poly­merization catalyst using the olefin polymerization catalyst component; a process for polymerizing olefin(s) which comprises polymerizing or copolymerizing olefin(s) in the presence of the olefin polymerization catalyst; and a film and an injection-molded article of polypropylene which is prepared by the process are also provided.

  此外，还提供了一种烯烃聚合催化剂组分，使用具有 2 至 5 个碳原子的直链α-烯烃和 3-甲基-1-丁烯中的每一种进行连续的初步聚合处理；一种使用该烯烃聚合催化剂组分的烯烃聚合催化剂；一种聚合烯烃的工艺，该工艺包括在该烯烃聚合催化剂存在的情况下聚合或共聚烯烃；以及一种由该工艺制备的聚丙烯薄膜和注塑制品。
• Process for polymerizing olefins and catalyst for polymerizing olefins
  申请人：MITSUI PETROCHEMICAL INDUSTRIES, LTD.

  公开号：EP0385765A2

  公开（公告）日：1990-09-05

  A catalyst for polymerization of an olefin, said catalyst being formed from [A] a solid titanium catalyst component com­prising magnesium, titanium, halogen and an electron donor as essential ingredients, [B] an organoaluminum compound catalyst com­ponent, and [C] an electron donor catalyst component com­prising at least two electron donors including an electron donor (1) and an electron donor (2), the MFR (a) of homopolypropylene obtained by using the electron donor (1) together with the solid titanium catalyst component [A] and the organoaluminum compound catalyst component [B] has the following relation to the MFR (b) of homo­polypropylene obtained by using the electron donor (2) under the same polymerization conditions as in the case of using the electron donor (1) log [MFR (b)/MFR (a)]≧1.5. This catalyst can give an olefin polymer having a broad molecular weight. Also provided is a process for poly­merizing or copolymerizing an olefin in the presence of the above catalyst.

  一种用于烯烃聚合的催化剂，所述催化剂由以下物质组成 [A] 固态钛催化剂组分，其主要成分包括镁、钛、卤素和电子供体、 [B] 一种有机铝化合物催化剂组分，以及 [C] 电子供体催化剂组分，由至少两个电子供体组成，包括电子供体 (1) 和电子供体 (2)，在与使用电子供体 (1) 相同的聚合条件下，使用电子供体 (1) 与固体钛催化剂组分 [A] 和有机铝化合物催化剂组分 [B] 一起得到的均聚丙烯的 MFR (a) 与使用电子供体 (2) 得到的均聚丙烯的 MFR (b) 具有如下关系 对数[MFR (b)/MFR (a)]≧1.5。 这种催化剂可以得到具有宽分子量的烯烃聚合物。还提供了一种在上述催化剂存在下聚合或共聚烯烃的工艺。