(β-methoxy-phenethyl)-carbamic acid ethyl ester

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: (β-methoxy-phenethyl)-carbamic acid ethyl ester
• 英文别名: (β-Methoxy-phenaethyl)-carbamidsaeure-aethylester；ethyl N-(2-methoxy-2-phenylethyl)carbamate
• 化学式: C₁₂H₁₇NO₃
• 分子量: 223.272
• InChiKey: ALWHDWBFAFDHCW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  1.7
• 重原子数：
  16
• 可旋转键数：
  6
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.42
• 拓扑面积：
  47.6
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  (β-methoxy-phenethyl)-carbamic acid ethyl ester 在 盐酸 作用下， 生成 2-methoxy-2-phenylethan-1-amine
  参考文献：
  名称：

  Jejuno-ileal atresia in identical twins: Report of a case

  摘要：

  Small intestinal atresia occurring in twins is extremely rare. The aims of this study are to report a case of identical twins with different types of jejunal atresia, to review six other pairs of twins, and discuss the etiology. Our ease was the seventh in which both twins were diagnosed to have jejuno-ileal atresia, Furthermore, they are also only the sixth and seventh patients known to survive, All the other published cases involved identical twins except one, Three pairs had different types of atresia and four pairs did not have any other anomalies. In addition, to date there have been no further indications of any other members of these families being affected with intestinal atresia, Therefore, we conclude that most such cases might be due to environmental influences during gestation.

  DOI：

  10.1007/s005950050619
• 作为产物：
  描述：

  methyl β-phenyl-β-methoxy-propionate 在 盐酸 、 一水合肼 、 sodium nitrite 作用下， 生成 (β-methoxy-phenethyl)-carbamic acid ethyl ester
  参考文献：
  名称：

  Jejuno-ileal atresia in identical twins: Report of a case

  摘要：

  Small intestinal atresia occurring in twins is extremely rare. The aims of this study are to report a case of identical twins with different types of jejunal atresia, to review six other pairs of twins, and discuss the etiology. Our ease was the seventh in which both twins were diagnosed to have jejuno-ileal atresia, Furthermore, they are also only the sixth and seventh patients known to survive, All the other published cases involved identical twins except one, Three pairs had different types of atresia and four pairs did not have any other anomalies. In addition, to date there have been no further indications of any other members of these families being affected with intestinal atresia, Therefore, we conclude that most such cases might be due to environmental influences during gestation.

  DOI：

  10.1007/s005950050619

文献信息

• Jejuno-ileal atresia in identical twins: Report of a case
  作者：Yutaro Matsumoto、Kazuhisa Komatsu、Tosiharu Tabata

  DOI：10.1007/s005950050619

  日期：2000.5

  Small intestinal atresia occurring in twins is extremely rare. The aims of this study are to report a case of identical twins with different types of jejunal atresia, to review six other pairs of twins, and discuss the etiology. Our ease was the seventh in which both twins were diagnosed to have jejuno-ileal atresia, Furthermore, they are also only the sixth and seventh patients known to survive, All the other published cases involved identical twins except one, Three pairs had different types of atresia and four pairs did not have any other anomalies. In addition, to date there have been no further indications of any other members of these families being affected with intestinal atresia, Therefore, we conclude that most such cases might be due to environmental influences during gestation.