Tributylphosphine-Catalyzed Stereoselective <i>O</i>-Vinylation of 2-Hydroxybenzaldehyde Derivatives
作者:Ali Ramazani、Vahid Azizkhani、Farideh Gouranlou
DOI:10.1080/10426500902922941
日期:2010.3.24
Protonation of the highly reactive 1:1 intermediates, produced in the reaction between tributylphosphine and alkyl acetylenecarboxylates by 2-hydroxybenzaldehyde derivatives, leads to vinyltributylphosphonium salts, which undergo a Michael addition reaction with conjugate base to produce corresponding phosphorus ylides. The phosphorus ylides convert to electron-poor O-vinyl ether derivatives under reaction conditions.