1-(2',3'-dichlorophenyl)-2-nitroethylene | 104433-13-8

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-(2',3'-dichlorophenyl)-2-nitroethylene
• 英文别名: 2,3-Dichlor-1-(β-nitrovinyl)-benzol；1,2-dichloro-3-(2-nitroethenyl)benzene
• CAS: 104433-13-8
• 化学式: C₈H₅Cl₂NO₂
• mdl: MFCD00297075
• 分子量: 218.039
• InChiKey: QDRLNSJTMBNERI-UHFFFAOYSA-N

物化性质

• 沸点：
  337.7±32.0 °C(Predicted)
• 密度：
  1.447±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  13
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  45.8
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  1-(2',3'-dichlorophenyl)-2-nitroethylene 在 sodium azide 作用下， 以 水 为溶剂， 以95%的产率得到4-(2,3-dichlorophenyl)-1H-1,2,3-triazole
  参考文献：
  名称：

  Cu @ g-C3N4在水上通过硝基烯烃/炔烃和叠氮化钠的[2 + 3]环加成反应催化合成NH-1,2,3-三唑

  摘要：

  在这里，我们报道了石墨聚合的C 3 N 4负载的CuCl 2（Cu @ g‐C 3 N 4）的制造，其特征在于粉末X射线衍射，场发射扫描电子显微镜，高分辨率透射电子显微镜，X射线光电子能谱研究。通过使用Cu @ g-C 3证明了通过硝基烯烃/苯基乙炔与叠氮化钠的1,3-二极性环加成反应进行水合成4-芳基-NH -1,2,3-三唑衍生物的高效且区域选择性的方案N 4作为坚固且可重复使用的催化剂。

  DOI：

  10.1002/cctc.201801524
• 作为产物：
  描述：

  2,3-二氯苯甲醛 在 乙酸铵 作用下， 以 硝基甲烷 、 溶剂黄146 为溶剂， 生成 1-(2',3'-dichlorophenyl)-2-nitroethylene
  参考文献：
  名称：

  Microbicidal compositions

  摘要：

  描述了新型微生物杀灭剂及其生产，其符合以下公式I ##STR1## 其中R为卤素，C.sub.1 -C.sub.6 -烷基或C.sub.1 -C.sub.6 -卤代烷基，n为0、1或2。这些新型化合物是有价值的活性物质，特别用于控制植物病原真菌和细菌。这些化合物适用于保护栽培植物和种子，并可优势用于保护储存的库存和食品。

  公开号：

  US04687861A1

文献信息

• Pd/C-Catalyzed Dehydrogenative [3+2] Cycloaddition for the Synthesis of Functionalized Tropanes
  作者：Hai-Jun Wang、Lei Guo、Cheng-Feng Zhu、Yun-Fei Luo、You-Gui Li、Xiang Wu

  DOI：10.1002/ejoc.201801147

  日期：2018.10.24

  Described is a Pd/C‐catalyzed dehydrogenative [3+2] cycloaddition for the synthesis of benzo‐fused tropanes. The reaction proceeds through a sequential Pd/C‐catalyzed dehydrogenative formation of azomethine ylides from amines and 1,3‐dipolar cycloaddition.

  描述了Pd / C催化的脱氢[3 + 2]环加成反应，用于合成苯并熔合的托烷。该反应通过胺的1,3-偶极环加成反应依次进行Pd / C催化的偶氮甲亚胺脱氢反应形成。
• Intermediates for the preparation of microficidal pyrroline derivatives
  申请人：Ciba-Geigy Corporation

  公开号：US04778901A1

  公开（公告）日：1988-10-18

  Intermediates for the production of microbicidal pyrrolines of the formula ##STR1## in which R is halogen, C.sub.1 -C.sub.6 -alkyl or C.sub.1 14 C.sub.6 -haloalkyl, and n is 0, 1 or 2, and a method of converting the pyrrolines to phytofungicidal pyrroles by oxidation with bromine or oxygen. Catalysts are provided for the oxidation with oxygen.

  用于制备具有以下公式的微生物杀菌吡咯烷的中间体 ##STR1## 其中R是卤素，C.sub.1-C.sub.6-烷基或C.sub.1-C.sub.6-卤代烷基，n为0、1或2，并提供一种通过溴化或氧气氧化将吡咯烷转化为植物真菌杀菌吡咯的方法。还提供了用于氧气氧化的催化剂。
• Method of and bait compositions for controlling mollusks
  申请人：AMERICAN CYANAMID COMPANY

  公开号：EP0312723A2

  公开（公告）日：1989-04-26

  This invention relates to methods of controlling mollusks with arylpyrrole compounds and to bait compositions containing a molluscicidally effective amount of an arylpyrrole compound.

  本发明涉及用芳基吡咯化合物控制软体动物的方法，以及含有对软体动物有效的芳基吡咯化合物的诱饵组合物。
• In search of diamine analogs of the α,α-diphenyl prolinol privileged chiral organocatalyst. Synthesis of diamine derivatives of α,α-diphenyl-(S)-prolinol and their application as organocatalysts in the asymmetric Michael and Mannich reactions
  作者：Gloria Reyes-Rangel、Jorge Vargas-Caporali、Eusebio Juaristi

  DOI：10.1016/j.tet.2015.11.032

  日期：2016.1

  This paper describes improved reaction conditions for the substitution of the hydroxyl group in (S)-diphenyl(pyrrolidin-2-yl)methanol by the azide group, which was then reduced to the diamine derivative. We examined two protecting groups (N-Bn and N-Boc) on the pyrrolidine nitrogen in order to functionalize the primary amino group into various amide, alkylated amine, sulfonamide, thiourea and triazole derivatives. Notably, carefully controlled conditions were required to generate the desired derivatives from the sterically hindered benzhydrylamine moiety. Unexpectedly, upon removal of the N-protecting group in derivatives containing electrophilic polar double bonds (C=S, C=O) cyclization took place, affording products such as amidines. The target compounds were evaluated as bifunctional organocatalysts in the asymmetric Michael and Mannich addition reactions. (S)-2-(Azidodiphenylmethyl) pyrrolidine (S)-7 was identified as the most efficient organocatalyst among the various diamine derivatives of alpha,alpha-diphenyl-(S)-prolinol prepared in this work. (C) 2015 Elsevier Ltd. All rights reserved.
• DABCO-mediated aza-Michael addition of 4-aryl-1H-1,2,3-triazoles to cycloalkenones. Regioselective synthesis of disubstituted 1,2,3-triazoles
  作者：Ujjawal Kumar Bhagat、Kamaluddin、Rama Krishna Peddinti

  DOI：10.1016/j.tetlet.2016.11.125

  日期：2017.1

  Aza-Michael addition of 4-aryl-1H-1,2,3-triazoles to 2-cycloalken-1-ones has been studied in the presence of DABCO as organic base. The reactions were carried out in acetonitrile at room temperature to provide 2,4-disubstituted 2H-1,2,3-triazoles as major adducts and 1,4-disubstituted 1H-1,2,3-triazoles as minor adducts. Though the reaction times are longer (4-8 days), the two regioisomers were separated by using column chromatography and the adducts were obtained in very good to excellent combined chemical yields. The electron-rich and electron-poor substituents on aryl moiety of 4-aryl-triazoles could tolerate the reaction conditions to afford the title adducts. (C) 2016 Elsevier Ltd. All rights reserved.