7-(Benzenesulfonyl)-7-(prop-2-en-1-yl)-1,4-dioxaspiro[4.5]decane | 138832-38-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 7-(Benzenesulfonyl)-7-(prop-2-en-1-yl)-1,4-dioxaspiro[4.5]decane
• 英文别名: 7-(benzenesulfonyl)-7-prop-2-enyl-1,4-dioxaspiro[4.5]decane
• CAS: 138832-38-9
• 化学式: C₁₇H₂₂O₄S
• 分子量: 322.425
• InChiKey: WTJAELXOBVKRON-UHFFFAOYSA-N

物化性质

• 沸点：
  483.4±45.0 °C(Predicted)
• 密度：
  1.23±0.1 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  2.8
• 重原子数：
  22
• 可旋转键数：
  4
• 环数：
  3.0
• sp3杂化的碳原子比例：
  0.53
• 拓扑面积：
  61
• 氢给体数：
  0
• 氢受体数：
  4

反应信息

• 作为反应物：
  描述：

  7-(Benzenesulfonyl)-7-(prop-2-en-1-yl)-1,4-dioxaspiro[4.5]decane 在 对甲苯磺酸 作用下， 以 氯仿 、 丙酮 为溶剂， 反应 10.0h， 以65%的产率得到3-Propenyl-2-cyclohexenone
  参考文献：
  名称：

  An Improved Method for the Syntheses of β-Substituted Cyclohexenones

  摘要：

  An improved method for the preparation of beta-substituted cyclohexenones is reported. Conditions were defined to effectuate the key desulfonylation-deketalization step in a mild manner. Several cyclohexenones bearing acid and/or base sensitive beta-substituents were prepared by the modified method in moderate to good yields.

  DOI：

  10.1080/00397919108021597
• 作为产物：
  描述：

  1,1-(ethylenedioxy)-3-(phenylsulfonyl)-cyclohexane 、 3-溴丙烯 在 lithium diisopropyl amide 作用下， 生成 7-(Benzenesulfonyl)-7-(prop-2-en-1-yl)-1,4-dioxaspiro[4.5]decane
  参考文献：
  名称：

  An Improved Method for the Syntheses of β-Substituted Cyclohexenones

  摘要：

  An improved method for the preparation of beta-substituted cyclohexenones is reported. Conditions were defined to effectuate the key desulfonylation-deketalization step in a mild manner. Several cyclohexenones bearing acid and/or base sensitive beta-substituents were prepared by the modified method in moderate to good yields.

  DOI：

  10.1080/00397919108021597

文献信息

• An Improved Method for the Syntheses of β-Substituted Cyclohexenones
  作者：Pei-Qiang Huang、Wei-Shan Zhou

  DOI：10.1080/00397919108021597

  日期：1991.12

  An improved method for the preparation of beta-substituted cyclohexenones is reported. Conditions were defined to effectuate the key desulfonylation-deketalization step in a mild manner. Several cyclohexenones bearing acid and/or base sensitive beta-substituents were prepared by the modified method in moderate to good yields.