Diisopropyl-phosphoramidous acid bis-(2,6-dichloro-phenyl) ester | 208458-85-9

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: Diisopropyl-phosphoramidous acid bis-(2,6-dichloro-phenyl) ester
• CAS: 208458-85-9
• 化学式: C₁₈H₂₀Cl₄NO₂P
• 分子量: 455.148
• InChiKey: VMYREYBEPUNNQN-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  8.1
• 重原子数：
  26.0
• 可旋转键数：
  7.0
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.33
• 拓扑面积：
  21.7
• 氢给体数：
  0.0
• 氢受体数：
  3.0

反应信息

• 作为反应物：
  描述：

  Diisopropyl-phosphoramidous acid bis-(2,6-dichloro-phenyl) ester 在 1,2,3,4,5,6,7,8-八硫杂环辛烷 、 1,8-二氮杂双环[5.4.0]十一碳-7-烯 作用下， 以 四氢呋喃 、 氘代氯仿 为溶剂， 反应 3.0h， 生成
  参考文献：
  名称：

  Imidazo-oxazaphosphorines as Precursors to Chiral Phosphite Triesters

  摘要：

  New bicyclic imidazo-oxazaphosphorines underwent a highly diastereoselective displacement of the imidazole moiety upon reaction with various alcohols, leading to chiral phosphite triesters as single diastereomers. The introduction of a nucleoside on this bicyclic structure was investigated by several routes, leading to new nucleoside building blocks.

  DOI：

  10.1080/07328319808003465
• 作为产物：
  描述：

  二氯-N,N-二异丙基亚磷酰胺 、 2,6-二氯苯酚钠 以 四氢呋喃 为溶剂， 反应 0.5h， 生成 Diisopropyl-phosphoramidous acid bis-(2,6-dichloro-phenyl) ester
  参考文献：
  名称：

  Imidazo-oxazaphosphorines as Precursors to Chiral Phosphite Triesters

  摘要：

  New bicyclic imidazo-oxazaphosphorines underwent a highly diastereoselective displacement of the imidazole moiety upon reaction with various alcohols, leading to chiral phosphite triesters as single diastereomers. The introduction of a nucleoside on this bicyclic structure was investigated by several routes, leading to new nucleoside building blocks.

  DOI：

  10.1080/07328319808003465