(1,2-bis(salicylideneaminooxy)ethane)

• 分子结构分类: 有机化合物 - 苯类化合物 - 酚类
• 英文名称: (1,2-bis(salicylideneaminooxy)ethane)
• 英文别名: 1,2-Bis(salicylideneaminooxy)ethane；2-[2-[(2-hydroxyphenyl)methylideneamino]oxyethoxyiminomethyl]phenol
• 化学式: C₁₆H₁₆N₂O₄
• 分子量: 300.314
• InChiKey: UOAFWGRREJJDCI-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3
• 重原子数：
  22
• 可旋转键数：
  7
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  83.6
• 氢给体数：
  2
• 氢受体数：
  6

反应信息

• 作为反应物：
  描述：

  (1,2-bis(salicylideneaminooxy)ethane) 、 zinc diacetate 以 not given 为溶剂， 以61%的产率得到[Zn3(1,2-bis(salicylideneaminooxy)ethane(2-))2(OAc)2]
  参考文献：
  名称：

  Cooperative Formation of Trinuclear Zinc(II) Complexes via Complexation of a Tetradentate Oxime Chelate Ligand, Salamo, and Zinc(II) Acetate

  摘要：

  Novel trinuclear zinc(II) complexes [Zn3L2(OAc)(2)] (L = salamo, 3-MeOsalamo) were synthesized, and their structures were determined by X-ray crystallography. Ligation of methoxy groups in the salamo ligand causes a significantly different coordination mode of the central zinc atom in the trinuclear system. The complexes between the salamo ligands and zinc(II) in methanol formed exclusively and very cooperatively. In contrast to other imine ligands, the mononuclear [ZnL] and other complexes are not observed at all.

  DOI：

  10.1021/ic049282k
• 作为产物：
  描述：

  1,2-二(氨氧基)乙烷 、 邻甲基苄醇 以 乙醇 为溶剂， 以83%的产率得到(1,2-bis(salicylideneaminooxy)ethane)
  参考文献：
  名称：

  肟基Salen型四齿配体对亚胺复分解反应具有高稳定性

  摘要：

  尽管Salen及其类似物在无机和有机金属化学中是通用的螯合配体，但由于C N键的重组，难以合成由两个不同的水杨基亚胺基部分组成的不对称salen衍生物。为了开发稳定的Salen型配体类似物，我们在O-烷基肟而不是亚胺基团的基础上合成了一系列新的配体salamo（= 1,2-双（水杨基亚氨基氧基）乙烷）。从相应的水杨醛2a - h制备了8种Salamo配体1a - h，以64-88％的产率获得了无色晶体。1a - c的晶体结构这表明肟-OH的形式比酮-NH的形式更为主要。的反应2A - ë用过量的1,2-二（氨氧基）乙烷，得到monooximes 3A - ë在59-86％，这进一步用不同的水杨醛反应，得到不对称的配体salamo 4 - 8为稳定晶体在51-70 ％。当萨拉莫衍生物1a和1b的混合物在H 2 O / MeCN（5:95）中于40°C处理时，没有反应发生。但是，Salen衍生

  DOI：

  10.1021/jo048030y

文献信息

• Synthesis and Characterization of Novel Ligands 1,2-Bis(salicylideneaminooxy)ethanes
  作者：Shigehisa Akine、Takanori Taniguchi、Tatsuya Nabeshima

  DOI：10.1246/cl.2001.682

  日期：2001.7

  Novel ligands 1,2-bis(salicylideneaminooxy)ethanes were synthesized. They were much more stable against exchange reactions of aldehyde units than the corresponding salen derivatives. They form stable complexes with a copper(II) ion, whose structures were crystallographically determined. Spectroscopic and electrochemical studies indicated that the complexes have lower LUMO levels than salen analogues

  合成了新的配体 1,2-双 (水杨基氨基氧基) 乙烷。它们对醛单元的交换反应比相应的沙仑衍生物更稳定。它们与铜 (II) 离子形成稳定的络合物，其结构由晶体学确定。光谱和电化学研究表明，这些配合物的 LUMO 水平低于 salen 类似物。
• Novel Thiosalamo Ligand as a Remarkably Stable N₂S₂ Salen-Type Chelate and Synthesis of a Nickel(II) Complex
  作者：Shigehisa Akine、Tatsuya Nabeshima

  DOI：10.1021/ic048347g

  日期：2005.3.1

  Novel N2S2 tetradentate chelate ligand H2tsalamo, which contains both thiol groups and C=N moieties, was synthesized as a remarkably stable compound. Complexation between H2tsalamo and nickel(II) acetate gave a square planar complex [Ni(tsalamo)] as dark brown crystals, whose structure was determined by X-ray crystallography. In contrast, the corresponding N2O2 ligands, salamo and 3-MeOsalamo, gave trinuclear

  合成了同时含有巯基和C = N部分的新型N2S2四齿螯合配体H2tsalamo，它是一种非常稳定的化合物。H 2 tsalamo和乙酸镍（II）之间的络合得到深褐色晶体形式的方形平面络合物[Ni（tsalamo）]，其结构通过X射线晶体学确定。相反，相应的N2O2配体salamo和3-MeOsalamo分别给出了三核和单核配合物，其中所有镍原子均具有八面体几何形状。
• Cooperative Formation of Trinuclear Zinc(II) Complexes via Complexation of a Tetradentate Oxime Chelate Ligand, Salamo, and Zinc(II) Acetate
  作者：Shigehisa Akine、Takanori Taniguchi、Tatsuya Nabeshima

  DOI：10.1021/ic049282k

  日期：2004.10.1

  Novel trinuclear zinc(II) complexes [Zn3L2(OAc)(2)] (L = salamo, 3-MeOsalamo) were synthesized, and their structures were determined by X-ray crystallography. Ligation of methoxy groups in the salamo ligand causes a significantly different coordination mode of the central zinc atom in the trinuclear system. The complexes between the salamo ligands and zinc(II) in methanol formed exclusively and very cooperatively. In contrast to other imine ligands, the mononuclear [ZnL] and other complexes are not observed at all.
• Oxime-Based Salen-Type Tetradentate Ligands with High Stability against Imine Metathesis Reaction
  作者：Shigehisa Akine、Takanori Taniguchi、Wenkui Dong、Sayuri Masubuchi、Tatsuya Nabeshima

  DOI：10.1021/jo048030y

  日期：2005.3.1

  are versatile chelate ligands in inorganic and organometallic chemistry, synthesis of unsymmetrical salen derivatives consisting of two different salicylideneimine moieties is difficult because of the CN bond recombination. To develop stable analogues of salen-type ligands, we synthesized a series of new ligands salamo (=1,2-bis(salicylideneaminooxy)ethane) on the basis of O-alkyl oxime instead of the

  尽管Salen及其类似物在无机和有机金属化学中是通用的螯合配体，但由于C N键的重组，难以合成由两个不同的水杨基亚胺基部分组成的不对称salen衍生物。为了开发稳定的Salen型配体类似物，我们在O-烷基肟而不是亚胺基团的基础上合成了一系列新的配体salamo（= 1,2-双（水杨基亚氨基氧基）乙烷）。从相应的水杨醛2a - h制备了8种Salamo配体1a - h，以64-88％的产率获得了无色晶体。1a - c的晶体结构这表明肟-OH的形式比酮-NH的形式更为主要。的反应2A - ë用过量的1,2-二（氨氧基）乙烷，得到monooximes 3A - ë在59-86％，这进一步用不同的水杨醛反应，得到不对称的配体salamo 4 - 8为稳定晶体在51-70 ％。当萨拉莫衍生物1a和1b的混合物在H 2 O / MeCN（5:95）中于40°C处理时，没有反应发生。但是，Salen衍生