1-<(Z)-cinnamyloxy>oct-2-yne

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 1-<(Z)-cinnamyloxy>oct-2-yne
• 英文别名: [(Z)-3-oct-2-ynoxyprop-1-enyl]benzene
• 化学式: C₁₇H₂₂O
• 分子量: 242.361
• InChiKey: MEDPGHSYZZSPHK-KAMYIIQDSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  4.9
• 重原子数：
  18
• 可旋转键数：
  7
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.41
• 拓扑面积：
  9.2
• 氢给体数：
  0
• 氢受体数：
  1

反应信息

• 作为产物：
  描述：

  1-溴-2辛炔 、 (Z)-肉桂醇 在 sodium hydride 作用下， 以 四氢呋喃 为溶剂， 以65%的产率得到1-<(Z)-cinnamyloxy>oct-2-yne
  参考文献：
  名称：

  Bicyclization of Enynes Using the Cp₂TiCl₂−Mg−BTC System:  A Practical Method to Bicyclic Cyclopentenones

  摘要：

  Bicyclic titanacycles 2 generated with the Cp2TiCl2-Mg-P(OEt)(3) system can be trapped with bis(trichloromethyl) carbonate (BTC) to give bicyclic cyclopentenones 3 in good yields. The titanacycle 2m was isolated and well-identified. Bicyclization of enynes containing 1,2-disubstituted olefin by this method gave good results with excellent stereoselectivity.

  DOI：

  10.1021/jo9810718

文献信息

• Bicyclization of Enynes Using the Cp₂TiCl₂−Mg−BTC System:  A Practical Method to Bicyclic Cyclopentenones
  作者：Zongbao Zhao、Yu Ding、Gang Zhao

  DOI：10.1021/jo9810718

  日期：1998.12.1

  Bicyclic titanacycles 2 generated with the Cp2TiCl2-Mg-P(OEt)(3) system can be trapped with bis(trichloromethyl) carbonate (BTC) to give bicyclic cyclopentenones 3 in good yields. The titanacycle 2m was isolated and well-identified. Bicyclization of enynes containing 1,2-disubstituted olefin by this method gave good results with excellent stereoselectivity.