12-hydroxyoctadecanoic acid vinyl ester | 152752-18-6

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 12-hydroxyoctadecanoic acid vinyl ester
• 英文别名: Vinyl 12-hydroxystearate；ethenyl 12-hydroxyoctadecanoate
• CAS: 152752-18-6
• 化学式: C₂₀H₃₈O₃
• 分子量: 326.52
• InChiKey: DAUXBFDFCKRQAW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  23
• 可旋转键数：
  18
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.85
• 拓扑面积：
  46.5
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  12-hydroxyoctadecanoic acid vinyl ester 在 4 A molecular sieve 作用下， 以 正己烷 为溶剂， 反应 26.0h， 生成 13,26-dihexyl-1,14-dioxacyclohexacosane-2,15-dione
  参考文献：
  名称：

  Lipase catalyzed formation of lactones via irreversible intramolecular acyltransfer

  摘要：

  The lipase catalyzed formation of lactones is greatly facilitated, if the conditions of irreversible acyltransfer are employed. While only insignificant amounts of lactones are obtained from hydroxy carboxylic acids (+/-)-1a-f or their methyl esters (+/-)-2a-f, considerable yields can be obtained, if the corresponding vinyl esters (+/-)-3a-f are used as substrates. Due to the enantioselectivities, displayed by the lipase from Pseudomonas sp., optically active products are formed.

  DOI：

  10.1016/s0957-4166(00)80147-0
• 作为产物：
  描述：

  乙酸乙烯酯 、 12-羟基硬脂酸 在 palladium diacetate 氢氧化钾 作用下， 反应 24.0h， 以83%的产率得到12-hydroxyoctadecanoic acid vinyl ester
  参考文献：
  名称：

  Synthesis of Hydroxycarboxylic Acid Vinyl Esters

  摘要：

  在醋酸乙烯酯和醋酸钯（II）作为催化剂存在的基本条件下，成功地将具有伯羟基或仲羟基官能团的羟基羧酸转化为相应的乙烯基酯。对以前经常干扰这些转化的副反应进行了研究，并对反应条件进行了优化，以达到最高的产品产率。

  DOI：

  10.1055/s-1994-25479

文献信息

• Vinyl chloride resin compositions, moulded products obtained therefrom, and methods of producing the compositions and molded products
  申请人：Chisso Corporation

  公开号：EP0635530A1

  公开（公告）日：1995-01-25

  A vinyl chloride resin composition comprises (a) 100 parts by weight of a crosslinkable vinyl chloride resin, or 100 parts by weight in total of 1 to 99 parts by weight of a crosslinkable vinyl chloride resin and 99 to 1 part by weight of a vinyl chloride resin; (b) 1 to 100 parts by weight of a polyol compound; and (c) as a crosslinking agent, 1 to 100 parts by weight of a blocked polyisocyanate compound.

  氯乙烯树脂组合物包括 (a) 100 份(重量)可交联氯乙烯树脂，或 1 至 99 份(重量)可交联氯乙烯树脂和 99 至 1 份(重量)氯乙烯树脂共 100 份(重量)； (b) 1 至 100 份（重量份數）多元醇化合物；及 (c) 1 至 100 份(重量)封端多异氰酸酯化合物作为交联剂。
• Vinyl chloride resin composition
  申请人：CHISSO CORPORATION

  公开号：EP0473426B1

  公开（公告）日：1996-10-16
• US5242965A
  申请人：——

  公开号：US5242965A

  公开（公告）日：1993-09-07
• Synthesis of Hydroxycarboxylic Acid Vinyl Esters
  作者：Mario Lobell、Manfred P. Schneider

  DOI：10.1055/s-1994-25479

  日期：——

  The conversion of hydroxycarboxylic acids with primary or secondary hydroxy functions into the corresponding vinyl esters was successfully achieved under basic conditions in presence of vinyl acetate and palladium(II) acetate as catalyst. Side reactions, which were previously frequently interfering with these transformations, have been studied and reaction conditions optimised to reach maximum product yield.

  在醋酸乙烯酯和醋酸钯（II）作为催化剂存在的基本条件下，成功地将具有伯羟基或仲羟基官能团的羟基羧酸转化为相应的乙烯基酯。对以前经常干扰这些转化的副反应进行了研究，并对反应条件进行了优化，以达到最高的产品产率。
• Lipase catalyzed formation of lactones via irreversible intramolecular acyltransfer
  作者：Mario Lobell、Manfred P. Schneider

  DOI：10.1016/s0957-4166(00)80147-0

  日期：1993.5

  The lipase catalyzed formation of lactones is greatly facilitated, if the conditions of irreversible acyltransfer are employed. While only insignificant amounts of lactones are obtained from hydroxy carboxylic acids (+/-)-1a-f or their methyl esters (+/-)-2a-f, considerable yields can be obtained, if the corresponding vinyl esters (+/-)-3a-f are used as substrates. Due to the enantioselectivities, displayed by the lipase from Pseudomonas sp., optically active products are formed.