α-Chlorobenzyl phenyl sulfoxide | 21128-89-2

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: α-Chlorobenzyl phenyl sulfoxide
• 英文别名: {[chloro(phenyl)methyl]sulfinyl}benzene；alpha-chlorobenzyl phenyl sulfoxide；α-Chlorbenzyliden-phenylsulfoxid；α-Chlor-benzyl-phenyl-sulfoxid；α-Chlorbenzyl-phenylsulfoxid；Phenyl-chlorbenzylsulfoxid；(Chloro-phenylmethyl)sulfinylbenzene；[benzenesulfinyl(chloro)methyl]benzene
• CAS: 21128-89-2
• 化学式: C₁₃H₁₁ClOS
• 分子量: 250.749
• InChiKey: OXLXBMKMKBBFAW-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.4
• 重原子数：
  16
• 可旋转键数：
  3
• 环数：
  2.0
• sp3杂化的碳原子比例：
  0.08
• 拓扑面积：
  36.3
• 氢给体数：
  0
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  α-Chlorobenzyl phenyl sulfoxide 生成 硫代苯甲酸 S-苯基酯
  参考文献：
  名称：

  Alkylation and silicon Pummerer rearrangement of chloromethyl phenyl sulfoxide. A thiol ester acyl anion equivalent

  摘要：

  DOI：

  10.1021/jo00407a040
• 作为产物：
  描述：

  苄基苯基硫醚 在 吡啶 、 (二氯碘)-苯 作用下， 生成 α-Chlorobenzyl phenyl sulfoxide
  参考文献：
  名称：

  α-卤代亚砜的合成

  摘要：

  亚砜与（二氯碘代）苯或与溴在吡啶存在下反应，得到相应的α-卤代亚砜。这里描述了α-卤代亚砜的一些反应。

  DOI：

  10.1039/p19720001883

文献信息

• Aryl 1-chloroalkyl sulfoxides as acyl anion equivalents: a new synthesis of vinyl sulfides, ketones, and diketones from aryl 1-chloroalkyl sulfoxides and α,ω-dichloro-α,ω-disulfinylalkanes
  作者：Tsuyoshi Satoh、Daisaku Taguchi、Chihiro Suzuki、Satoshi Fujisawa

  DOI：10.1016/s0040-4020(00)01015-2

  日期：2001.1

  anhydride and NaI in acetone at low temperature afforded vinyl sulfides in high yields. The vinyl sulfides were converted to ketones by hydrolysis with HClO4 in refluxing 1,4-dioxane in good yields. In this procedure, the lithiated aryl 1-chloroalkyl sulfoxides acted as acyl anion equivalents. The procedure was extended to a synthesis of α,ω-diketones starting from α,ω-dichloro-α,ω-disulfinylalkanes. The procedure

  在低温下用三氟乙酸酐和NaI处理由芳基1-氯烷基亚砜通过与碘代烷烃的烷基化反应而合成的芳基α-氯烷基亚砜，可以高产率得到乙烯基硫化物。在回流的1，4-二恶烷中，通过用HClO 4水解，将乙烯基硫化物转化为酮。在该程序中，锂化的芳基1-氯烷基亚砜起酰基阴离子当量的作用。该程序扩展到从α，ω-二氯-α，ω-二亚磺酰基烷烃开始合成α，ω-二酮。当α，ω-二亚磺酰基烷烃的碳链长度大于四个时，发现该方法行之有效，并且发现二酮的收率有些变化（60-80％）。
• Imide-Catalyzed Oxidation System: Sulfides to Sulfoxides and Sulfones
  作者：Naohiro Fukuda、Tomomi Ikemoto

  DOI：10.1021/jo100719w

  日期：2010.7.2

  A new combination system, the oxidation of sulfides using aqueous NaOCl in the presence of a catalytic amount of imide under two-phase conditions, has been developed. The combination effectively converts various sulfides to the corresponding sulfoxides and sulfones. It was deduced that the imide could react with NaOCl to produce N-chloroimide, which would play roles of both the active oxidizing reagent

  已经开发了一种新的组合系统，在两相条件下，在催化量的酰亚胺存在下，使用NaOCl水溶液氧化硫化物。该组合有效地将各种硫化物转化为相应的亚砜和砜。推测该酰亚胺可以与NaOCl反应生成N-氯酰亚胺，这将同时起到活性氧化剂和相转移催化剂的作用。
• Sulfoxide derivative and process for its preparation
  申请人：Sagami Chemical Research Center

  公开号：US04029712A1

  公开（公告）日：1977-06-14

  A novel sulfoxide derivative of the general formula ##STR1## wherein R.sup.1 and R.sup.3 are the same or different, and each represents and alkyl group having 1 to 4 carbon atoms, a phenyl group or a halo- or methyl-substituted phenyl group, R.sup.2 is a hydrogen atom, a lower alkyl group, benzyl group, or a p-methoxy- or p-bromo-benzyl group, R.sup.1 and R.sup.2, together, may form an alkylene group containing 3 carbon atoms, and X is an oxygen or sulfur atom, and to a process for its preparation.

  通式为##STR1##的一种新型亚砜衍生物，其中R.sup.1和R.sup.3相同或不同，分别代表具有1至4个碳原子的烷基基团、苯基或卤代苯基或甲基取代的苯基，R.sup.2是氢原子、较低的烷基基团、苄基或对甲氧基或对溴基苄基，R.sup.1和R.sup.2一起可以形成含有3个碳原子的烷基基团，X是氧原子或硫原子，以及其制备方法。
• Process for the Production of Organic Oxides
  申请人：Ikemoto Tomomi

  公开号：US20090054655A1

  公开（公告）日：2009-02-26

  The present invention provides a method for producing an organic oxide, wherein a substrate is oxidized using hypohalous acid, hypohalous acid salt, chlorine, bromine or iodine in the presence of water and a catalytic amount of a compound represented by the following formula (I): R 1 —X 1 —NY—R 2 , wherein: X 1 represents —CO— or —SO 2 —; Y represents a hydrogen atom, a potassium atom, a sodium atom, a chlorine atom, a bromine atom or an iodine atom; R 1 represents a substituted or unsubstituted hydrocarbon group, —NYR 3 group or —OR 3 group (in the formulae, R 3 represents a substituted or unsubstituted hydrocarbon group, and Y represents the same meaning as defined above); and R 2 represents a hydrogen atom or —CO—R 4 group (in the formula, R 4 represents a substituted or unsubstituted hydrocarbon group, —NYR 5 group or —OR 5 group (in the formulae, R 5 represents a substituted or unsubstituted hydrocarbon group, and Y represents the same meaning as defined above)); or R 1 and R 4 may bind to each other to form a further substituted or unsubstituted nitrogen-containing heterocyclic ring.

  本发明提供了一种制备有机氧化物的方法，其中在水和式(I)化合物的催化下，使用次氯酸、次氯酸盐、氯、溴或碘对基质进行氧化，式(I)中：X1代表—CO—或—SO2—；Y代表氢原子、钾原子、钠原子、氯原子、溴原子或碘原子；R1代表取代或未取代的碳氢基团、—NYR3基团或—OR3基团（在公式中，R3代表取代或未取代的碳氢基团，Y的含义与上述定义相同）；R2代表氢原子或—CO—R4基团（在公式中，R4代表取代或未取代的碳氢基团、—NYR5基团或—OR5基团（在公式中，R5代表取代或未取代的碳氢基团，Y的含义与上述定义相同））；或者R1和R4可以结合形成进一步的取代或未取代的含氮杂环。
• Benzimidazole derivatives, and their production and use
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0132606A1

  公开（公告）日：1985-02-13

  An insecticidal and/or acaricidal composition which comprises as an active ingredient an effective amount of a benzimidazole derivative of the formula: wherein R, is a hydrogen atom or a lower alkyl group, R2 and R3 are, the same or different, each a hydrogen atom, a halogen atom, a nitro group, a cyano group or an optionally substituted lower alkyl, lower alkenyl, lower alkynyl, cyclo(lower)alkyl, lower alkoxy, lower alkenyloxy, lower alkynyloxy, cyclo(lower)alkoxy, lower alkylthio, lower alkenylthio, lower alkynylthio, cyclo(lower)alkylthio, di(lower)alkylamino, lower alkylsulfonyl or lower alkylsulfinyl group, or R2 and R3 are combined togetherto form an optionally substituted 5- or 6-membered, saturated or unsaturated ring optionally having not more than two oxygen atoms or sulfur atoms within the ring and X is an oxygen atom, a sulfur atom, a methylene group, a sulfonyl group, a sulfinyl group or an imino group, and an inert carrier or diluent.

  一种杀虫和/或杀螨组合物，其活性成分包括有效量的式苯并咪唑衍生物： 其中 R 是氢原子或低级烷基，R2 和 R3 相同或不同，各自是氢原子、卤素原子、硝基、氰基或任选取代的低级烷基、低级烯基、低级炔基、环(低级)烷基、低级烷氧基、低级烯氧基、低级炔氧基、环(低级)烷氧基、低级烷硫基、低级烯硫基、低级炔硫基、环(低级)烷硫基、二（低级）烷基氨基、低级烷基磺酰基或低级烷基亚磺酰基，或 R2 和 R3 结合在一起形成任选取代的 5 或 6 元饱和或不饱和环，环内任选具有不超过两个氧原子或硫原子，X 为氧原子、硫原子、亚甲基、磺酰基、亚磺酰基或亚氨基，以及惰性载体或稀释剂。