2,4,6-tris-(2,4-dimethyl-phenyl)-[1,3,5]triazine | 14117-13-6

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,4,6-tris-(2,4-dimethyl-phenyl)-[1,3,5]triazine
• 英文别名: tris-(2,4-dimethyl-phenyl)-[1,3,5]triazine；Tris-(2,4-dimethyl-phenyl)-[1,3,5]triazin；2,4,6-tris(2,4-dimethylphenyl)-1,3,5-triazine；trisxylyl-triazine
• CAS: 14117-13-6
• 化学式: C₂₇H₂₇N₃
• 分子量: 393.531
• InChiKey: LIQXXKWZQWSIBQ-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  7.1
• 重原子数：
  30
• 可旋转键数：
  3
• 环数：
  4.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  38.7
• 氢给体数：
  0
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  盐酸 、 2,4,6-tris-(2,4-dimethyl-phenyl)-[1,3,5]triazine 生成 2,4-二甲基苯甲酸
  参考文献：
  名称：

  Scholl; Noerr, Chemische Berichte, 1900, vol. 33, p. 1056

  摘要：

  DOI：
• 作为产物：
  描述：

  2,4,6-三溴-1,3,5-三嗪 、 间二甲苯 在 二硫化碳 、 三氯化铝 作用下， 生成 2,4,6-tris-(2,4-dimethyl-phenyl)-[1,3,5]triazine
  参考文献：
  名称：

  v.Meyer,E.; Naebe, Journal fur praktische Chemie (Leipzig 1954), 1910, vol. <2>82, p. 537

  摘要：

  DOI：

文献信息

• Process for isolation of monophenolic-bisaryl triazines
  申请人：——

  公开号：US20030013879A1

  公开（公告）日：2003-01-16

  This invention relates to a novel, efficient, economic and general-purpose process for isolating monophenolic-bisaryl triazine compounds from polyphenolic-triazines compounds and other impurities. More specifically, this invention relates to a process for isolating the monophenolic-bisaryl triazine compounds by contacting it with a base, an alcohol or a hydrocarbon solvent.

  这项发明涉及一种新颖、高效、经济且通用的工艺，用于从多酚-三嗪化合物和其他杂质中分离单酚基-双芳基-三嗪化合物。更具体地说，这项发明涉及一种通过与碱、醇或烃溶剂接触来分离单酚基-双芳基-三嗪化合物的工艺。
• [EN] NOVEL CYCLOALKYL'B! CONDENSED INDOLES<br/>[FR] NOUVEAUX INDOLES CYCLOALKYL'B! CONDENSES
  申请人：SMITHKLINE BEECHAM CORP

  公开号：WO2005023245A1

  公开（公告）日：2005-03-17

  The present invention relates to compounds of formula (I) that are useful in the treatment of human papillomaviruses, and also to the methods for the making and use of such compounds.

  本发明涉及式（I）的化合物，其在人类乳头瘤病毒的治疗中有用，并且还涉及制备和使用这些化合物的方法。
• Process for making triazine UV absorbers using lewis acids and reaction promoters
  申请人：CYTEC Technologies Corp.

  公开号：US20010020094A1

  公开（公告）日：2001-09-06

  It has been now surprisingly discovered after extensive research that 2-halo-4,6-bisaryl-1,3,5-triazine can be prepared with unprecedented selectivity, efficiency, mild conditions, and in high yield by the reaction of cyanuric halide with aromatics in the presence of at least one Lewis acid and at least one reaction promoter. This reaction is also unprecedently general as a variety of aromatics can be used to produce a wide selection of 2-halo-4,6-bisaryl-1,3,5-triazines. The novel approach includes the use of the reaction promoters in combination with at least one Lewis acid under certain reaction conditions to promote the formation of 2-halo-4,6-bisaryl-1,3,5-triazine compounds from cyanuric halide. Preferably, the Lewis acids and reaction promoters are combined to form a complex. 2-Halo-4,6-bisaryl-1,3,5-triazines are key intermediates for making 2-(2-oxyaryl)-4,6-bisaryl-1,3,5-triazine class of UV absorbers.

  经过广泛的研究，令人惊讶地发现，通过氰尿酸卤化物与芳香族化合物在至少一种路易斯酸和至少一种反应促进剂的存在下反应，可以以前所未有的选择性、效率、温和条件和高产率制备2-卤代-4,6-双芳基-1,3,5-三嗪。该反应具有前所未有的广泛性，因为可以使用各种芳香族化合物来生产各种2-卤代-4,6-双芳基-1,3,5-三嗪。新的方法包括在特定反应条件下，将反应促进剂与至少一种路易斯酸结合使用，促进从氰尿酸卤化物中形成2-卤代-4,6-双芳基-1,3,5-三嗪化合物。最好将路易斯酸和反应促进剂组合形成复合物。2-卤代-4,6-双芳基-1,3,5-三嗪是制备2-(2-氧基芳基)-4,6-双芳基-1,3,5-三嗪类紫外线吸收剂的关键中间体。
• Process for making triazine UV absorbers using Lewis acids and reaction promoters
  申请人：CYTEC Industries Corp.

  公开号：US20020013463A1

  公开（公告）日：2002-01-31

  It has been now surprisingly discovered after extensive research that 2-halo-4,6-bisaryl-1,3,5-triazine can be prepared with unprecedented selectivity, efficiency, mild conditions, and in high yield by the reaction of cyanuric halide with aromatics in the presence of at least one Lewis acid and at least one reaction promoter. This reaction is also unprecedently general as a variety of aromatics can be used to produce a wide selection of 2-halo-4,6-bisaryl-1,3,5-triazines. The novel approach includes the use of the reaction promoters in combination with at least one Lewis acid under certain reaction conditions to promote the formation of 2-halo-4,6-bisaryl-1,3,5-triazine compounds from cyanuric halide. Preferably, the Lewis acids and reaction promoters are combined to form a complex. 2-Halo-4,6-bisaryl-1,3,5-triazines are key intermediates for making 2-(2-oxyaryl)-4,6-bisaryl-1,3,5-triazine class of UV absorbers.

  经过广泛的研究，惊人地发现了一种前所未有的选择性、效率、温和条件和高产率的方法，通过氰尿酸卤化物与芳香族化合物在至少一种路易斯酸和至少一种反应促进剂的存在下反应，制备2-卤代-4,6-双芳基-1,3,5-三嗪。这种反应也是前所未有的普适性，因为可以使用各种芳香族化合物来产生广泛的2-卤代-4,6-双芳基-1,3,5-三嗪选择。新方法包括在特定反应条件下使用反应促进剂与至少一种路易斯酸相结合，促进从氰尿酸卤化物中形成2-卤代-4,6-双芳基-1,3,5-三嗪化合物。最好是将路易斯酸和反应促进剂组合成复合物。2-卤代-4,6-双芳基-1,3,5-三嗪是制造2-(2-氧基芳基)-4,6-双芳基-1,3,5-三嗪类紫外线吸收剂的关键中间体。
• Process for making 2-(2,4,-dihydroxyphenyl) or 2-(2,4-dialkoxyphenyl)-4,6-bisaryl-1,3,5-triazines
  申请人：Cytec Technology Corp.

  公开号：US06225468B1

  公开（公告）日：2001-05-01

  Provided is a new process for the preparation of compositions containing at least one triazine ultraviolet light absorber.

  提供了一种制备至少含有一种三嗪紫外线吸收剂组分的组合物的新工艺。