2,3,4-三溴苯甲酸 | 36667-05-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 2,3,4-三溴苯甲酸
• 英文名称: 2,3,4-tribromo-benzoic acid
• 英文别名: 2,3,4-Tribrom-benzoesaeure；2,3,4-tribromobenzoic acid
• CAS: 36667-05-7
• 化学式: C₇H₃Br₃O₂
• 分子量: 358.812
• InChiKey: JWHSTVSAXLKNAZ-UHFFFAOYSA-N

物化性质

• 熔点：
  197-198 °C
• 沸点：
  391.9±42.0 °C(Predicted)
• 密度：
  2.383±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  3.5
• 重原子数：
  12
• 可旋转键数：
  1
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.0
• 拓扑面积：
  37.3
• 氢给体数：
  1
• 氢受体数：
  2

反应信息

• 作为反应物：
  描述：

  2,3,4-三溴苯甲酸 在 copper aluminum 氘氧化钠 作用下， 反应 0.5h， 生成 benzoic-2,3,4-d3 acid
  参考文献：
  名称：

  Tashiro, Masashi; Nakayama, Kouji; Fukata, Gouki, Journal of the Chemical Society. Perkin transactions I, 1983, # 10, p. 2315 - 2318

  摘要：

  DOI：
• 作为产物：
  描述：

  2,3,4-tribromo-5-methyl-aniline 在 硝酸 作用下， 生成 2,3,4-三溴苯甲酸
  参考文献：
  名称：

  Cohen; Dutt, Journal of the Chemical Society, 1914, vol. 105, p. 514

  摘要：

  DOI：

文献信息

• PROCESS FOR PRODUCING AMINOALKYLSULFONIC ACID AND METHOD OF SALT EXCHANGE FOR SALT THEREOF
  申请人：Wako Pure Chemical Industries, Ltd.

  公开号：EP1548002A1

  公开（公告）日：2005-06-29

  The present invention relates to a method for efficiently producing an aminoalkylsulfonic acid in an industrial scale, and provides    "a process for producing an aminoalkylsulfonic acid represented by the general formula [2]:    wherein R1 and R2 are each independently a hydrogen atom, an alkyl group, an aryl group or an aralkyl group; and R3 and R4 are each independently a hydrogen atom or an alkyl group, comprising reacting an aminoalkylsulfonate salt represented by the general formula [1]:    wherein M is an alkali metal atom, an organic ammonium ion or an ammonium ion; and R1 to R4 are the same as described above,    an aqueous solution thereof, or a solution dissolving any one of them in a water-soluble organic solvent, selected from alcohols having 1 to 3 carbon atoms, carboxylic acids having 2 to 12 carbon atoms and dimethylformamide, with an organic acid; and    a method of salt exchange for an aminoalkylsulfonate salt represented by the general formula [1']:    wherein M' is an alkali metal atom, an organic ammonium ion or an ammonium ion; and R1 and R4 are the same as described above, comprising reacting an aminoalkylsulfonate salt represented by the above general formula [2] with a hydroxide represented by the general formula [6]:         M'OH     [6]    wherein M' is the same as described above, in an alcohol or water".

  本发明涉及一种在工业规模上高效生产氨基磺酸的方法，并提供“一种生产由通式[2]表示的氨基磺酸的方法：其中R1和R2分别是氢原子、烷基、芳基或芳基烷基；R3和R4分别是氢原子或烷基的氨基磺酸盐发生反应所得的方法，通式[1]表示如下：其中M是碱金属原子、有机铵离子或铵离子；R1至R4与上述相同，其水溶液或将任何一种溶解于水溶性有机溶剂中的溶液，所选的有1至3个碳原子的醇、有2至12个碳原子的羧酸和二甲基甲酰胺，与有机酸反应；以及氨基磺酸盐交换的方法，通式[1']表示如下：其中M'是碱金属原子、有机铵离子或铵离子；R1和R4与上述相同，包括将上述通式[2]表示的氨基磺酸盐与通式[6]表示的氢氧化物发生反应：M'OH [6]其中M'与上述相同，在醇或水中”。
• PROCESS FOR PRODUCING ESTER COMPOUND
  申请人：Imazeki Shigeaki

  公开号：US20100324314A1

  公开（公告）日：2010-12-23

  PROBLEM To provide an environmentally-friendly method for producing industrially an ester compound. SOLUTION The present invention is a method for producing an ester compound which comprises subjecting a carboxylic acid and an alcohol to dehydration-condensation reaction using an involatile acid catalyst and then removing the residual acid catalyst by bringing a weak basic substance into contact with the residual acid catalyst.

  问题提供一种生产工业酯化合物的环保方法。 解决方案是一种生产酯化合物的方法，包括将羧酸和醇经过脱水缩合反应，使用一种不挥发的酸催化剂，然后通过将弱碱性物质与残留的酸催化剂接触来去除残留的酸催化剂。
• 4-benzoylisoxazoles and their use as herbicides
  申请人：Rhone-Poulenc Argriculture Limited

  公开号：US05658858A1

  公开（公告）日：1997-08-19

  The invention relates to 4-benzoylisoxazole compounds, compositions containing them, a process for preparation, and their use as herbicides.

  该发明涉及4-苯甲酰异噁唑化合物，含有它们的组合物，制备过程以及它们作为除草剂的用途。
• [EN] PREPARATION OF 5-ACYLAMINO-2,4,6-TRIIODO- OR TRIBROMO-BENZOIC ACID DERIVATIVES
  申请人：BRACCO INDUSTRIA CHIMICA S.P.A.

  公开号：WO1988009328A1

  公开（公告）日：1988-12-01

  (EN) A process for the preparation of 5-acylamino-2,4,6-triiodo or tribromo-benzoic acid derivatives of formula (I), wherein X is I or Br, R is H or a variously substituted alkyl, or a group of formula (II), wherein X has the above meanings; Y is hydroxy, alkoxy, hydroxyalkoxy, alkylamino or hydroxyalkylamino; Z may be the same as COY or it is hydroxyalkylaminocarbonyl provided that at least one of the two acyl or R groups is hydroxy-substituted, which process comprises the rearrangement of the corresponding 5-(alkylaminocarbonyl-alkoxy)-2,4,6-triiodo or tribromo-benzoic acid derivatives, in the presence of bases.(FR) Procédé pour la préparation de dérivés de 5-acylamino-2,4,6-triiodo ou tribromo-acide benzoïque de formule (I) dans laquelle X est I ou Br, R est H ou un alkyle diversement substitué, ou bien un groupe de formule (II) où X a les notations précitées, Y est hydroxy, alkoxy, hydroxyalkoxy, alkylamino ou hydroxyalkylamino; Z peut être identique à COY ou bien est hydroxyalkylaminocarbonyle, à condition qu'au moins un des deux groupes acyle ou R soit substitué par de l'hydroxy. Ledit procédé consiste à réagencer en présence de bases les dérivés correspondants de 5-(alkylaminocarbonyl-alkoxy)-2,4,6-triiodo ou tribromo-acide benzoïque.

  一种制备式(I)的5-酰胺基-2,4,6-三碘或三溴苯甲酸衍生物的方法，其中X为I或Br，R为H或各种取代基的烷基，或者为式(II)的基团，其中X具有上述含义；Y为羟基、烷氧基、羟基烷氧基、烷基氨基或羟基烷基氨基；Z可以与COY相同，也可以是羟基烷基氨基羰基，前提是两个酰基或R基中至少有一个是羟基取代的，该方法包括在碱的存在下重排相应的5-(烷氨基羰基烷氧基)-2,4,6-三碘或三溴苯甲酸衍生物。
• Process for producing of an aminoalkylsulfonic acid and a method of salt exchange for a salt thereof
  申请人：Kimura Takuhiro

  公开号：US20050261370A1

  公开（公告）日：2005-11-24

  A process for producing an aminoalkylsulfonic acid of formula [2]: wherein R 1 and R 2 are each independently hydrogen, alkyl, aryl or aralkyl; and R 3 and R 4 are each independently hydrogen or alkyl, comprising reacting an aminoalkylsulfonate salt of formula [1]: wherein M is alkali metal, organic ammonium or ammonium ion; and R 1 to R 4 are as described above, an aqueous solution thereof, or a solution dissolving any one of them in a water-soluble organic solvent, selected from alcohols having 1 to 3 carbon, carboxylic acids having 2 to 12 carbon and dimethylformamide, with an organic acid; and a method of salt exchange for an aminoalkylsulfonate salt of formula [1′]: wherein M′ is alkali metal, organic ammonium or ammonium ion; and R 1 and R 4 are as described above, comprising reacting the aminoalkylsulfonate salt formula [2] with a hydroxide of formula [6]: M′OH  [6] wherein M′ is as described above, in alcohol or water.

  一种生产化学式[2]的氨基烷基磺酸的方法：其中R1和R2各自独立地表示氢、烷基、芳香基或芳基烷基；R3和R4各自独立地表示氢或烷基，包括反应化学式[1]的氨基烷基磺酸盐：其中M为碱金属、有机铵或铵离子；R1至R4如上所述，其水溶性有机溶剂中的水溶性溶液或溶解其中任何一种的溶液，所选的有机酸；以及化学式[1']的氨基烷基磺酸盐的盐交换方法：其中M'为碱金属、有机铵或铵离子；R1和R4如上所述，包括将氨基烷基磺酸盐化学式[2]与化学式[6]的氢氧化物反应：M'OH [6]，其中M'如上所述，在醇或水中。