2,3-dihydroxyethylbenzamide | 55522-92-4

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 英文名称: 2,3-dihydroxyethylbenzamide
• 英文别名: N-ethyl-2,3-dihydroxybenzamide；2,3-Dihydroxy-N-ethylbenzamid
• CAS: 55522-92-4
• 化学式: C₉H₁₁NO₃
• 分子量: 181.191
• InChiKey: RRYTWUYOUOYLGW-UHFFFAOYSA-N

物化性质

• 沸点：
  350.5±32.0 °C(Predicted)
• 密度：
  1.265±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  1.3
• 重原子数：
  13
• 可旋转键数：
  2
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.22
• 拓扑面积：
  69.6
• 氢给体数：
  3
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  bis(acetylacetonate)oxovanadium 、 2,3-dihydroxyethylbenzamide 在 KOH 作用下， 以 乙醇 为溶剂， 生成
  参考文献：
  名称：

  微生物铁转运的配位化学。49. 钒 (IV) 肠杆菌素复合物：结构、光谱和电化学表征

  摘要：

  铁载体肠杆菌素 (H 6 ent) 已从二甲基甲酰胺 (DMF) 溶液中结晶为化合物 K 2 [V(ent)]-IDMF 中的钒 (IV) 复合物。金属离子的假八面体配位是通过三个邻苯二酚基团并具有近似的C 3 分子点对称性。几何形状介于三棱柱和八面体之间，扭曲角为 28 o 。为了比较，已确定 N-乙基-2,3-二羟基苯甲酰胺 (H 2 eba) 的无约束复合物。

  DOI：

  10.1021/ja00058a032
• 作为产物：
  描述：

  3-[(2,3-dimethoxyphenyl)carbonyl]thiazolidine-2-thione 在 sodium hydroxide 、 三溴化硼 作用下， 以 二氯甲烷 、 氯仿 、 水 为溶剂， 反应 48.0h， 生成 2,3-dihydroxyethylbenzamide
  参考文献：
  名称：

  微生物铁转运的配位化学。49. 钒 (IV) 肠杆菌素复合物：结构、光谱和电化学表征

  摘要：

  铁载体肠杆菌素 (H 6 ent) 已从二甲基甲酰胺 (DMF) 溶液中结晶为化合物 K 2 [V(ent)]-IDMF 中的钒 (IV) 复合物。金属离子的假八面体配位是通过三个邻苯二酚基团并具有近似的C 3 分子点对称性。几何形状介于三棱柱和八面体之间，扭曲角为 28 o 。为了比较，已确定 N-乙基-2,3-二羟基苯甲酰胺 (H 2 eba) 的无约束复合物。

  DOI：

  10.1021/ja00058a032

文献信息

• Pyrimidine derivatives, their production and use
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0426476A1

  公开（公告）日：1991-05-08

  A pyrimidine derivative useful as a herbicide is represented by the formula wherein each of R1 and R2, which may be the same or different, represents a hydrogen atom, a C1-C6 alkyl group, a C3-C6 alkenyl group, a C3-C6 alkynyl group, a halo C1-C6 alkyl group, a C1-C6 alkoxy C1-C6 alkyl group, a C3-C6 alkenyloxy C,-C6 alkyl group, a C3-C6 alkynyloxy C1-C6 alkyl group, a C1-C6 alkoxycarbonyl Ci-C6 alkyl group, a C3-C6 alkenyloxycarbonyl C1-C6 alkyl group, a C3-C6 alkynyloxycarbonyl C1-C6 alkyl group, a cyano C1-C6 alkyl group, a group represented by the formula, (in which each of R5 and R6, which may be the same or different, represents a hydrogen atom, a C1-C6 alkyl group, a C3-C6 alkenyl group or a C3-C6 alkynyl group, and n represents an integer of 1, 2, 3, or 4), a group represented by the formula, (in which n is as defined above, R7 represents a C1-C6 alkyl group, a C3-C6 alkenyl group or a C3-C6 alkynyl group, and m represents an integer of 0, 1 or 2), a cyclo C3-C8 alkyl group, or an optionally substituted phenyl group, an optionally substituted benzyl group, or R1 and R2, bonded together at their ends, form an optionally substituted C4-C7 alkylene group or an optionally substituted C3-C6 alkylene group containing hetero atom; the hetero atom in R' and R2 means a nitrogen atom, an oxygen atom or a sulfur atom; each of R3 and R4, which may be the same or different, represents a C1-C6 alkyl group, a C1-C6 alkoxy group, a halo C1-C6 alkoxy group or a halogen atom; X represents an oxygen atom or a sulfur atom; Z represents N or CY4; each of Y1, Y2, Y3, which may be the same or different, represents a hydrogen atom, a halogen atom, a C1-C6 alkyl group, or a Ci-C6 alkoxy group; and Y4 represents a hydrogen atom, a hydroxyl group, a mercapto group, a nitro group, a halogen atom, a C1-C6 alkyl group, a C2-C6 alkenyl group, a C2-C6 alkynyl group, a C1-C6 alkoxy group, a C3-C6 alkenyloxy group, a C3-C6 alkynyloxy group, a halo C1-C6 alkyl group, a halo C2-C6 alkenyl group, a halo C2-C6 alkynyl group, a halo C1-C6 alkoxy group, a halo C3-C6 alkenyloxy group, a halo C3-C6 alkynyloxy group, a C1-C6 alkoxy C1-C6 alkyl group, a C3-C6 alkenyloxy C1-C6 alkyl group, a C3-C6 alkynyloxy C1-C6 alkyl group, a cyano group, a formyl group, a carboxyl group, a C1-C6 alkoxycarbonyl group, a C3-C6 alkenyloxycarbonyl group, a alkynyloxycarbonyl group; an optionally substituted phenyl group, an optionally substituted phenoxy group, an optionally substituted phenylthio group, an optionally substituted benzyloxy group, an optionally substituted benzylthio group, a group represented by the formula, (in which R5 and R6 are as defined above), a group represented by the formula, (in which R5 and R6 are as defined above), (in which R7 and m are as defined above), a group represented by the formula, (in which R7 and X are as defined above), or a group represented by the formula, (in which R7, m and n are as defined above), each optionally substituted group in the above being substituted with a C1-C6 alkyl group, a C1-C6 alkoxy group, a halo C1-C6 alkyl group, a C1-C6 alkoxycarbonyl group or a halogen atom.

  一种可用作除草剂的嘧啶衍生物由以下式子表示 其中R1和R2可以相同或不同，各自代表氢原子、C1-C6烷基、C3-C6烯基、C3-C6炔基、卤代C1-C6烷基、C1-C6烷氧基C1-C6烷基、C3-C6烯氧基C、-C1-C6烷基、C1-C6烯氧基 C1-C6烷基、C3-C6炔氧基 C1-C6烷基、氰基 C1-C6烷基、由式、 (其中 R5 和 R6（可以相同或不同）分别代表氢原子、C1-C6 烷基、C3-C6 烯基或 C3-C6 烷炔基，且 n 代表 1、2、3 或 4 的整数）、由式表示的基团、 (其中 n 如上定义，R7 代表 C1-C6 烷基、C3-C6 烯基或 C3-C6 烷炔基，m 代表 0、1 或 2 的整数）、环 C3-C8 烷基或任选取代的苯基、任选取代的苄基，或 R1 和 R2 在其末端键合形成任选取代的 C4-C7 亚烷基或任选取代的含有杂原子的 C3-C6 亚烷基；R' 和 R2 中的杂原子是指氮原子、氧原子或硫原子； R3 和 R4（可以相同或不同）各自代表 C1-C6 烷基、C1-C6 烷氧基、卤代 C1-C6 烷氧基或卤素原子； X 代表氧原子或硫原子； Z 代表 N 或 CY4； Y1、Y2、Y3（可以相同或不同）各自代表氢原子、卤素原子、C1-C6 烷基或 Ci-C6 烷氧基；Y4 代表氢原子、羟基、巯基、硝基、卤素原子、C1-C6 烷基、C2-C6 烯基、C2-C6 炔基、C1-C6 烷氧基、C3-C6 烯氧基、C3-C6 炔氧基、卤代 C1-C6 烷基、卤代 C2-C6 烯基、卤代 C2-C6 炔基、卤代 C1-C6 烷氧基、卤代 C3-C6 烯氧基、卤代 C3-C6 炔氧基、C1-C6 烷氧基 C1-C6 烷基、C3-C6 烯氧基 C1-C6 烷基、C3-C6 炔氧基 C1-C6 烷基、氰基、甲酰基、羧基、C1-C6 烷氧基羰基、C3-C6 烯氧基羰基、炔氧基羰基；任选取代的苯基、任选取代的苯氧基、任选取代的苯硫基、任选取代的苄氧基、任选取代的苄硫基、由式表示的基团、 (其中 R5 和 R6 如上文所定义）、由以下式子表示的基团 (其中 R5 和 R6 如上定义）所代表的基团、 (式所代表的基团（其中 R7 和 m 如上所定义）、 由式所代表的基团 (其中 R7 和 X 如上所定义）代表的基团，或由式 (其中 R7、m 和 n 如上定义）所代表的基团，上述各任选取代基团均被 C1-C6 烷基、C1-C6 烷氧基、卤代 C1-C6 烷基、C1-C6 烷氧羰基或卤原子取代。
• Pyrimidine derivative
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0469711A1

  公开（公告）日：1992-02-05

  A pyrimidine derivative has the formula, wherein each of R1 and R2, which may be the same or different, is C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkoxy or halogen; R3 is hydrogen, C1-C6 alkyl, phenyl or phenyl substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl, nitro and halogen; each of R4 and R5, which may be the same or different, is hydrogen, C1-C6 alkyl, halo C1-C6 alkyl, phenyl, phenyl substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl, nitro and halogen, benzyl, pyridyl, pyridyl substituted with at least one member selected from the group consisting of Ci-C6 alkyl, Ci-C6 alkoxy, halo Ci-C6 alkyl, Ci-C6 alkoxycarbonyl, nitro and halogen, quinolinyl, quinolinyl substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl, nitro and halogen, C1-C6 alkylcarbonyl, C1-C6 alkoxycarbonyl, and wherein A1 is C4-C7 alkylene, C4-C7 alkylene substituted with C1-C6 alkyl, a group of the formula, -(CH2)q-A2-(CH2)r-, wherein A2 is S, O, wherein R9 is hydrogen, C1-C6 alkyl, q and r are integers and satisfy the criteria, 3 ≦ q + r ≦ 6, q ≧ 1, r ≧ 1, or a group of the formula, -(CR2)q-A2-(CH2)r-, substituted with C1-C6 alkyl wherein q, r and A2 are as defined above; or a group of the formula, wherein A is C2-C4 alkylene or C2-C4 alkylene substituted with C1-C6 alkyl, or a group of the formula, wherein A is as defined above; X is oxygen or sulfur; Z is nitrogen or CY4; each of Y1, Y2 and Y3, which may be the same or different, is hydrogen, halogen, C1-C6 alkyl or C1-C6 alkoxy; and Y4 is hydrogen, hydroxyl, mercapto, nitro, halogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 alkoxy, C3-C6 alkenyloxy, C3-C6 alkynyloxy, halo C1-C6 alkyl, halo C2-C6 alkenyl, halo C2-C6 alkynyl, halo C1-C6 alkoxy, halo C3-C6 alkenyloxy, halo C3-C6 alkynyloxy, C1-C6 alkoxy C1-C6 alkyl, C3-C6 alkenyloxy C1-C6 alkyl,C3-C6 alkynyloxy C1-C6 alkyl, cyano, formyl, carboxyl, C1-C6 alkoxycarbonyl, C3-C6 alkenyloxycarbonyl, C3-C6 alkynyloxycarbonyl, phenyl, phenyl substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, phenoxy, phenoxy substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, phenylthio, phenylthio substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, benzyloxy, benzyloxy substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, benzylthio, benzylthio substituted with at least one member selected from the group consisting of C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkyl, C1-C6 alkoxycarbonyl and halogen, wherein each of R8 and R6, which may be the same or different, is hydrogen, C1-C6 alkyl, C3-C6 alkenyl or C3-C6 alkynyl, wherein R8 and R6 are as defined above, wherein R7 is C1-C6 alkyl, C3-C6 alkenyl or C3-C6 alkynyl and m is an integer of 0, 1 or 2, wherein X1 is oxygen or sulfur, and R7 is as defined above, or wherein R7 and m are as defined above, and n is an integer from 1 to 4.

  嘧啶衍生物具有以下式子 其中 R1 和 R2（可以相同或不同）分别为 C1-C6 烷基、C1-C6 烷氧基、卤代 C1-C6 烷氧基或卤素； R3 是氢、C1-C6 烷基、苯基或至少被一个选自 C1-C6 烷基、C1-C6 烷氧基、卤代 C1-C6 烷基、C1-C6 烷氧羰基、硝基和卤素的成员取代的苯基； R4 和 R5（可以相同或不同）各自为氢、C1-C6 烷基、卤代 C1-C6 烷基、苯基、被至少一个选自由 C1-C6 烷基、C1-C6 烷氧基、卤代 C1-C6 烷基、C1-C6 烷氧羰基、硝基和卤素组成的组的成员取代的苯基、苄基、吡啶基、被至少一个选自由 Ci-C6 烷基、C1-C6 烷氧基、卤代 C1-C6 烷氧羰基、硝基和卤素组成的组的成员取代的吡啶基、C1-C6烷基、C1-C6烷氧基、卤代 C1-C6烷基、C1-C6烷氧羰基、硝基和卤素组成的组中的至少一个成员取代的喹啉基、喹啉基、C1-C6烷基羰基、C1-C6烷氧羰基、硝基和卤素组成的组中的至少一个成员取代的喹啉基、C1-C6烷基羰基、C1-C6烷氧羰基，以及 其中 A1 是 C4-C7 亚烷基、被 C1-C6 烷基取代的 C4-C7 亚烷基、式中的基团-(CH2)q-A2-(CH2)r-、 其中 A2 是 S、O 其中 R9 是氢、C1-C6 烷基，q 和 r 是整数且满足 3 ≦ q + r ≦ 6、q ≧ 1、r ≧ 1 的条件，或者是式中的基团、 -(CR2)q-A2-(CH2)r-、 被 C1-C6 烷基取代，其中 q、r 和 A2 如上定义；或式中的基团、 其中 A 为 C2-C4 亚烷基或被 C1-C6 烷基取代的 C2-C4 亚烷基，或如下式的基团 其中 A 如上定义； X 是氧或硫 Z 是氮或 CY4 Y1、Y2 和 Y3（可以相同或不同）各自是氢、卤素、C1-C6 烷基或 C1-C6 烷氧基；以及 Y4 是氢、羟基、巯基、硝基、卤素、C1-C6 烷基、C2-C6 烯基、C2-C6 炔基、C1-C6 烷氧基、C3-C6 烯氧基、C3-C6 炔氧基、卤代 C1-C6 烷基、卤代 C2-C6 烯基、卤代 C2-C6 炔基、卤代 C1-C6 烷氧基、卤代 C3-C6 烯氧基、卤代 C3-C6 炔氧基、C1-C6 烷氧基 C1-C6 烷基、C3-C6 烯氧基 C1-C6 烷基、C3-C6 烷氧基 C1-C6 烷基、氰基、甲酰基、羧基、C1-C6 烷氧基羰基、C3-C6 烯氧基羰基、C3-C6 烷炔氧基羰基、苯基、被至少一个选自 C1-C6 烷基、C1-C6 烷氧基、卤代 C1-C6 烷基、C1-C6 烷氧基羰基和卤素组成的组的成员取代的苯基、苯氧基、至少被选自由 C1-C6 烷基、C1-C6 烷氧基、卤代 C1-C6 烷基、C1-C6 烷氧羰基和卤素组成的组中的一个成员取代的苯氧基， 苯硫基，至少被选自由 C1-C6 烷基、C1-C6 烷氧基、卤代 C1-C6 烷基、C1-C6 烷氧羰基和卤素组成的组中的一个成员取代的苯硫基， 苄氧基、苄氧基、至少被选自由 C1-C6 烷基、C1-C6 烷氧基、卤代 C1-C6 烷基、C1-C6 烷氧羰基和卤素组成的组中的一个成员取代的苄氧基、苄硫基、至少被选自由 C1-C6 烷基、C1-C6 烷氧基、卤代 C1-C6 烷基、C1-C6 烷氧羰基和卤素组成的组中的一个成员取代的苄硫基、 其中 R8 和 R6（可以相同或不同）各自为氢、C1-C6 烷基、C3-C6 烯基或 C3-C6 烷炔基、 其中 R8 和 R6 如上定义、 其中 R7 是 C1-C6 烷基、C3-C6 烯基或 C3-C6 烷炔基，m 是 0、1 或 2 的整数、 其中 X1 为氧或硫，R7 如上文所定义，或 其中 R7 和 m 如上定义，n 为 1 至 4 的整数。
• Pyrimidine derivatives and their use as herbicides
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0457505A2

  公开（公告）日：1991-11-21

  A pyrimidine derivative has the formula, wherein A is C3-C8 cycloalkyl C1-C6 alkyl, C3-C8 cycloalkyl C1-C6 alkyl substituted with at least one member selected from the group consisting of C1-C6 alkyl and halogen, C3-C6 oxacycloalkyl, C3-C6 oxacycloalkyl substituted with at least one member selected from the group consisting of C1-C6 alkyl and halogen, C3-C6 oxacydoalkyl C1-C6 alkyl, C3-C6 oxacycloalkyl C1-C6 alkyl substituted with at least one member selected from the group consisting of C1-C6 alkyl and halogen, C3-C5 dioxacycloalkyl, C3-C5 dioxacycloalkyl substituted with at least one member selected from the group consisting of C1-C6 alkyl and halogen, C3-C5 dioxacycloalkyl C1-C6 alkyl or C2-C5 dioxacycloalkyl C1-C6 alkyl substituted with at least one member selected from the group consisting of C1-C6 alkyl and halogen ; each of R1 and R2, which may be the same or different, is C1-C6 alkyl, C1-C6 alkoxy, halo C1-C6 alkoxy or halogen ; X is oxygen or sulfur ; Z is nitrogen or CY4; each of Y1, Y2 and Y3, which may be the same or different, is hydrogen, halogen, C1-C6 alkyl or C1-C6 alkoxy; and Y4 is hydrogen, hydroxyl, mercapto, nitro, halogen, C1-C6 alkyl, C2-C6 alkenyl, C2-C6 alkynyl, C1-C6 alkoxy, C3-C6 alkenyloxy, C3-C6 alkynyloxy, halo C1-C6 alkyl, halo C2-C6 alkenyl, halo C2-C6 alkynyl, halo C1-C6 alkoxy, halo C3-C6 alkenyloxy, halo C3-C6 alkynyloxy, C1-C6 alkoxy C1-C6 alkyl, C3-C6 alkenyloxy C1-C6 alkyl, C3-C6 alkynyloxy C1-C6 alkyl, cyano, formyl, carboxyl, C1-C6 alkoxycarbonyl, C3-C6 alkenyloxycarbonyl, C3-C6 alkynyloxycarbonyl, phenyl, phenyl substituted with at least one member

  一种嘧啶衍生物具有以下式子 其中 A 是 C3-C8 环烷基 C1-C6 烷基、被至少一个选自由 C1-C6 烷基和卤素组成的组的成员取代的 C3-C8 环烷基 C1-C6 烷基、C3-C6 氧代环烷基、被至少一个选自由 C1-C6 烷基和卤素组成的组的成员取代的 C3-C6 氧代环烷基、C3-C6 氧代烷基 C1-C6 烷基、C3-C5 二氧环烷基、C3-C5 二氧环烷基、C3-C5 二氧环烷基、C3-C5 二氧环烷基 C1-C6 烷基或 C2-C5 二氧环烷基 C1-C6 烷基被至少一个选自 C1-C6 烷基和卤素的成员取代； R1 和 R2（可以相同或不同）各自为 C1-C6 烷基、C1-C6 烷氧基、卤代 C1-C6 烷氧基或卤素； X 是氧或硫； Z 是氮或 CY4； Y1、Y2 和 Y3（可以相同或不同）各自是氢、卤素、C1-C6 烷基或 C1-C6 烷氧基；以及 Y4 是氢、羟基、巯基、硝基、卤素、C1-C6 烷基、C2-C6 烯基、C2-C6 炔基、C1-C6 烷氧基、C3-C6 烯氧基、C3-C6 炔氧基、卤代 C1-C6 烷基、卤代 C2-C6 烯基、卤代 C2-C6 炔基、卤代 C1-C6 烷氧基、卤代 C3-C6 烯氧基、卤代 C3-C6 烷氧基、C1-C6 烷氧基 C1-C6烷基、C3-C6 烯氧基 C1-C6烷基、C3-C6 烷炔氧基 C1-C6烷基、氰基、甲酰基、羧基、C1-C6 烷氧基羰基、C3-C6 烯氧基羰基、C3-C6 烷炔氧基羰基、苯基、至少被一个成员取代的苯基
• Pyrimidine derivatives
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0468690A1

  公开（公告）日：1992-01-29

  A pyrimidine derivative has the formula, wherein each of R¹ and R², which may be the same or different, is C₁-C₆ alkyl, C₁-C₆ alkoxy, halo C₁-C₆ alkoxy or halogen;    R³ is hydrogen or C₁-C₆ alkyl;    R⁴ is C₁-C₆ alkyl, halo C₁-C₆ alkyl, benzyl, phenyl or phenyl substituted with at least one member selected from the group consisting of C₁-C₆ alkyl, C₁-C₆ alkoxy, halo C₁-C₆ alkyl, C₁-C₆ alkoxycarbonyl, nitro and halogen;    X is oxygen or sulfur;    Z is nitrogen or CY⁴;    each of Y¹, Y² and Y³, which may be the same or different, is hydrogen, halogen, C₁-C₆ alkyl or C₁-C₆ alkoxy; and    Y⁴ is hydrogen, hydroxyl, mercapto, nitro, halogen, C₁-C₆ alkyl, C₂-C₆ alkenyl, C₂-C₆ alkynyl, C₁-C₆ alkoxy, C₃-C₆ alkenyloxy, C₃-C₆ alkynyloxy, halo C₁-C₆ alkyl, halo C₂-C₆ alkenyl, halo C₂-C₆ alkynyl, halo C₁-C₆ alkoxy, halo C₃-C₆ alkenyloxy, halo C₃-C₆ alkynyloxy, C₁-C₆ alkoxy C₁-C₆ alkyl, C₃-C₆ alkenyloxy C₁-C₆ alkyl, C₃-C₆ alkynyloxy C₁-C₆ alkyl, cyano, formyl, carboxyl, C₁-C₆ alkoxycarbonyl, C₃-C₆ alkenyloxycarbonyl, C₃-C₆ alkynyloxycarbonyl, phenyl, phenyl substituted with at least one member selected from the group consisting of C₁-C₆ alkyl, C₁-C₆ alkoxy, halo C₁-C₆ alkyl, C₁-C₆ alkoxycarbonyl and halogen, phenoxy, phenoxy substituted with at least one member selected from the group consisting of C₁-C₆ alkyl, C₁-C₆ alkoxy, halo C₁-C₆ alkyl, C₁-C₆ alkoxycarbonyl and halogen, phenylthio, phenylthio substituted with at least one member selected from the group consisting of C₁-C₆ alkyl, C₁-C₆ alkoxy, halo C₁-C₆ alkyl, C₁-C₆ alkoxycarbonyl and halogen, benzyloxy, benzyloxy substituted with at least one member selected from the group consisting of C₁-C₆ alkyl, C₁-C₆ alkoxy, halo C₁-C₆ alkyl, C₁-C₆ alkoxycarbonyl and halogen, benzylthio, benzylthio substituted with at least one member selected from the group consisting of C₁-C₆ alkyl, C₁-C₆ alkoxy, halo C₁-C₆ alkyl, C₁-C₆ alkoxycarbonyl and halogen, wherein each of R⁵ and R⁶, which may be the same or different, is hydrogen, C₁-C₆ alkyl, C₃-C₆ alkenyl or C₃-C₆ alkynyl, wherein R⁵ and R⁶ are as defined above, wherein R⁷ is C₁-C₆ alkyl, C₃-C₆ alkenyl or C₃-C₆ alkynyl and m is an integer of 0, 1 or 2, wherein X¹ is oxygen or sulfur, and R⁷ is as defined above, or wherein R⁷ and m are as defined above, and n is an integer from 1 to 4.

  嘧啶衍生物的化学式为 其中 R¹ 和 R² 可以相同或不同，各自为 C₁-C₆烷基、C₁-C₆烷氧基、卤代 C₁-C₆烷氧基或卤素； R³ 是氢或 C₁-C₆ 烷基； R⁴ 是 C₁-C₆ 烷基、卤代 C₁-C₆ 烷基、苄基、苯基或至少被选自 C₁-C₆ 烷基的一个成员取代的苯基、C₁-C₆烷氧基、卤代 C₁-C₆烷基、C₁-C₆烷氧羰基、硝基和卤素； X 是氧或硫 Z 是氮或 CY⁴； Y¹、Y² 和 Y³ （可以相同或不同）各自是氢、卤素、C₁-C₆ 烷基或 C₁-C₆ 烷氧基；以及 Y⁴ 是氢、羟基、巯基、硝基、卤素、C₁-C₆ 烷基、C₂-C₆ 烯基、C₂-C₆ 炔基、C₁-C₆ 烷氧基、C₃-C₆ 烯氧基、C₃-C₆ 烷炔氧基、卤代 C₁-C₆ 烷基、卤代 C₂-C₆ 烯基、卤代 C₂-C₆ 烷基、卤代 C₁-C₆ 烷氧基、卤代 C₃-C₆ 烯氧基、卤代 C₃-C₆ 烷炔氧基、C₁-C₆ 烷氧基 C₁-C₆ 烷基、C₃-C₆烯氧基 C₁-C₆烷基、C₃-C₆炔氧基 C₁-C₆烷基、氰基、甲酰基、羧基、C₁-C₆烷氧基羰基、C₃-C₆烯氧基羰基、C₃-C₆炔氧基羰基、苯基、被至少一个选自 C₁-C₆ 烷基、C₁-C₆ 烷氧基、卤代 C₁-C₆ 烷基、C₁-C₆ 烷氧羰基和卤素组成的组的成员取代的苯基、苯氧基、至少被选自 C₁-C₆ 烷基、C₁-C₆ 烷氧基、卤代 C₁-C₆ 烷基、C₁-C₆ 烷氧羰基和卤素组成的组中的一个成员取代的苯氧基， 苯硫基被至少一个选自 C₁-C₆ 烷基、C₁-C₆ 烷氧基、卤代 C₁-C₆ 烷基、C₁-C₆ 烷氧羰基和卤素组成的组的成员取代的苯硫基， 苄氧基、被至少一个选自 C₁-C₆烷基、C₁-C₆烷氧基、卤代 C₁-C₆烷基、C₁-C₆烷氧羰基和卤素组成的组的成员取代的苄氧基、苄硫基被至少一个选自 C₁-C₆ 烷基、C₁-C₆ 烷氧基、卤代 C₁-C₆ 烷基、C₁-C₆ 烷氧羰基和卤素组成的组的成员取代的苄硫基、 其中 R⁵ 和 R⁶ 可以相同或不同，各自为氢、C₁-C₆ 烷基、C₃-C₆ 烯基或 C₃-C₆炔基、 其中 R⁵ 和 R⁶ 如上文所定义、 其中 R⁷ 是 C₁-C₆ 烷基、C₃-C₆ 烯基或 C₃-C₆ 烷基，且 m 是 0、1 或 2 的整数、 其中 X¹ 为氧或硫，且 R⁷ 如上文所定义，或 其中 R⁷ 和 m 如上文所定义，且 n 为 1 至 4 的整数。
• N-acyldihydroquinoline derivatives as herbicides
  申请人：SUMITOMO CHEMICAL COMPANY, LIMITED

  公开号：EP0579469A2

  公开（公告）日：1994-01-19

  Novel N-acyldihydroquinoline derivatives represented by the formula (I),    wherein each of R¹, R² and R³, which may be the same or different, represents a hydrogen atom; a halogen atom; a C₁-C₆ alkyl group; a C₁-C₆ alkoxy group; a a halo-C₁-C₆ alkyl group; a halo-C₁-C₆ alkoxy group; a (C₁-C₆ alkoxy)carbonyl group; a C₁-C₆ alkylthio group; a C₁-C₆ alkylamino group; a di(C₁-C₆ alkyl)amino group; a phenyl group; or a phenoxy group,    each of R⁴ and R⁵, which may be the same or different, represents a hydrogen atom or a C₁-C₆ alkyl group, or R⁴ and R⁵ are bonded together at their ends to form a C₂-C₅ alkylene group,    R⁶ represents a hydrogen atom; a halogen atom; an amino group; a C₁-C₆ alkylamino group; a di(C₁-C₆ alkyl)amino group; a (C₁-C₆ alkoxy)carbonylamino group; a cyano group; or a group represented by the formula, -C(=O)-Y-R⁷ (wherein Y represents an oxygen atom or a sulfur atom and R⁷ represents a hydrogen atom; a C₁-C₁₀ alkyl group; a C₂-C₁₀ alkenyl group; a C₂-C₁₀ alkynyl group; a halo-C₁-C₁₀ alkyl group; a halo-C₂-C₁₀ alkenyl group; a halo-C₂-C₁₀ alkynyl group; a C₃-C₁₀ cycloalkyl group; a C₃-C₁₀ cycloalkenyl group; a C₁-C₁₀ alkoxy-C₁-C₁₀ alkyl group; a C₁-C₁₀ alkylamino-C₁-C₁₀ alkyl group; a di(C₁-C₁₀ alkyl)amino-C₁-C₁₀ alkyl group; a furyl-C₁-C₁₀ alkyl group; a thienyl-C₁-C₁₀ alkyl group; a C₁-C₁₀ alkylamino group; a di(C₁-C₁₀ alkyl)amino group; -N=CH(C₁-C₁₀ alkyl) group; group; or a phenyl group optionally substituted with at least one member selected from the group consisting of (C₁-C₆ alkoxy)carbonyl groups, halogen atoms and C₁-C₆ alkyl groups; or a phenyl-C₁-C₆ alkyl group optionally substituted with at least one member selected from the group consisting of (C₁-C₆ alkoxy)carbonyl groups, halogen atoms and C₁-C₆ alkyl groups); or a group represented by the formula, (wherein each of R⁸ and R⁹, which may be the same or different, represents a hydrogen atom; a C₁-C₆ alkyl group; a C₂-C₆ alkenyl group; a C₂-C₆ alkynyl group; a halo-C₁-C₆ alkyl group; a halo-C₂-C₆ alkenyl group; a halo-C₂-C₆ alkynyl group; a C₃-C₆ cycloalkyl group; a C₃-C₆ cycloalkenyl group; an amino group; a C₁-C₆ alkylamino group; a di(C₁-C₆ alkyl)amino group; or a phenyl group optionally substituted with at least one member selected from the group consisting of halogen atoms and C₁-C₆ alkyl groups; or a phenyl-C₁-C₆ alkyl group optionally substituted with at least one member selected from the group consisting of halogen atoms and C₁-C₆ alkyl groups),    X represents CH or a nitrogen atom, a method for producing the same and their use as herbicides. The N-acyldihydroquinoline derivatives have herbicidal activity and selectivity between crops and weeds and therefore, can be used as an active ingredient for herbicides.

  由式 (I) 代表的新型 N-酰基二氢喹啉衍生物、 其中 R¹、R² 和 R³（可以相同或不同）各自代表氢原子；卤素原子；C₁-C₆ 烷基；C₁-C₆ 烷氧基；卤代-C₁-C₆ 烷基；卤代-C₁-C₆烷氧基；(C₁-C₆烷氧基)羰基；C₁-C₆烷硫基；C₁-C₆烷氨基；二(C₁-C₆烷基)氨基；苯基；或苯氧基、 R⁴ 和 R⁵ （可以相同或不同）各自代表氢原子或 C₁-C₆ 烷基，或 R⁴ 和 R⁵ 在其末端键合形成 C₂-C₅ 亚烷基、 R⁶ 代表氢原子；卤素原子；氨基；C₁-C₆ 烷基氨基；二(C₁-C₆ 烷基)氨基；(C₁-C₆ 烷氧基)羰基氨基；氰基；或由式-C(=O)-Y-R⁷代表的基团（其中 Y 代表氧原子或硫原子，R⁷ 代表氢原子；C₁-C₁₀ 烷基； C₂-C₁₀ 烯基； C₂-C₁₀ 炔基； 卤代 C₁-C₁₀ 烷基；卤代-C₂-C₁₀ 烯基； 卤代-C₂-C₁₀ 炔基； C₃-C₁₀ 环烷基； C₃-C₁₀ 环烯基； C₁-C₁₀ 烷氧基-C₁-C₁₀ 烷基； C₁-C₁₀ 烷基氨基-C₁-C₁₀ 烷基；二(C₁-C₁₀烷基)氨基-C₁-C₁₀烷基； 呋喃基-C₁-C₁₀烷基； 噻吩基-C₁-C₁₀烷基； C₁-C₁₀烷基氨基； 二(C₁-C₁₀烷基)氨基； -N=CH(C₁-C₁₀烷基)基团； 基团； 或至少被选自(C₁-C₆烷氧基)羰基、卤素原子和 C₁-C₆ 烷基组成的组中的一个成员任选取代的苯基；或苯基-C₁-C₆烷基，可任选被至少一个选自(C₁-C₆烷氧基)羰基、卤素原子和 C₁-C₆烷基组成的组的成员取代；） 或由以下式子代表的基团 (其中 R⁸ 和 R𠞙 可以相同或不同，各自代表氢原子；C₁-C₆ 烷基；C₂-C₆ 烯基；C₂-C₆ 炔基；卤代-C₁-C₆烷基； 卤代-C₂-C₆烯基； 卤代-C₂-C₆炔基； C₃-C₆环烷基； C₃-C₆环烯基； 氨基；C₁-C₆烷基氨基；二(C₁-C₆烷基)氨基；或至少被一个选自卤素原子和 C₁-C₆烷基的成员取代的苯基；或苯基-C₁-C₆烷基，可任选被至少一个选自由卤素原子和 C₁-C₆ 烷基组成的组中的成员取代）、 X代表CH或氮原子、生产方法及其作为除草剂的用途。 N-acyldihydroquinoline 衍生物具有除草活性和对作物和杂草的选择性，因此可用作除草剂的活性成分。