2-hydroxy-2-methyl-decanoic acid | 855213-35-3

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-hydroxy-2-methyl-decanoic acid
• 英文别名: C-Methyl-C-octyl-glykolsaeure；2-Hydroxy-2-methyl-decansaeure；2-Hydroxy-2-methyl-caprinsaeure；Methyl-n-octyl-glykolsaeure；α-Oxy-α-methyl-caprinsaeure；2-Oxy-decan-carbonsaeure-(2)；2-Hydroxy-2-methyldecanoic acid
• CAS: 855213-35-3
• 化学式: C₁₁H₂₂O₃
• 分子量: 202.294
• InChiKey: LRSHFEVKLTXXTL-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  3.3
• 重原子数：
  14
• 可旋转键数：
  8
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.91
• 拓扑面积：
  57.5
• 氢给体数：
  2
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-hydroxy-2-methyl-decanoic acid 、 乙醇 在 盐酸 作用下， 生成 2-hydroxy-2-methyl-decanoic acid ethyl ester
  参考文献：
  名称：

  5,5-Dialkyl-2,4-oxazolidinediones^1,2

  摘要：

  DOI：

  10.1021/ja01854a019
• 作为产物：
  描述：

  2-hydroxy-2-methyl-decanoic acid amide 在 盐酸 作用下， 生成 2-hydroxy-2-methyl-decanoic acid
  参考文献：
  名称：

  5,5-Dialkyl-2,4-oxazolidinediones^1,2

  摘要：

  DOI：

  10.1021/ja01854a019

文献信息

• Process for obtaining an organic acid from an organic acid ammonium salt, an organic acid amide, or an alkylamine organic acid complex
  申请人：——

  公开号：US20030029711A1

  公开（公告）日：2003-02-13

  Disclosed herein are methods for the recovery of an organic acid, such as a heat stable lactic acid, from a feed stream comprising at least one of an organic acid amide, an organic acid ammonium salt, or an alkylamine-organic acid complex. The feed stream that comprises the organic acid amide, organic acid ammonium salt, or alkylamine-organic acid complex is mixed with at least one azeotroping agent. The azeotroping agent is a hydrocarbon capable of forming at least one azeotrope with the organic acid that is produced by the thermal decomposition of the amide, ammonium salt, or complex in the feed stream. Preferably the azeotrope is a heteroazeotrope. The mixture comprising the feed stream and the azeotroping agent is heated to produce a vapor stream that comprises the azeotrope. The vapor stream can be condensed to a liquid stream, and the organic acid is recovered in the liquid stream that is produced. When the azeotrope comprising the organic acid is a heteroazeotrope, the vapor stream can be condensed into a liquid stream, which can be separated into a first phase and a second phase. The first phase contains the highest concentration of organic acid and the second phase comprises azeotroping agent. The organic acid can be further purified and/or concentrated from the separated first phase or from the liquid stream.

  本文公开了一种从包含有机酸酰胺、有机酸铵盐或烷基胺-有机酸复合物的进料流中回收有机酸（例如热稳定乳酸）的方法。将含有有机酸酰胺、有机酸铵盐或烷基胺-有机酸复合物的进料流与至少一种共沸剂混合。该共沸剂是一种烃类，能够与在进料流中热分解产生的有机酸形成至少一个共沸物。最好的情况是共沸物是杂共沸物。将混合物加热以产生包含共沸物的蒸汽流。蒸汽流可以冷凝成液流，并在所产生的液流中回收有机酸。当包含有机酸的共沸物是杂共沸物时，蒸汽流可以冷凝成液流，该液流可以分成第一相和第二相。第一相含有最高浓度的有机酸，第二相包含共沸剂。可以从分离的第一相或液流中进一步纯化和/或浓缩有机酸。
• PRESSURE-SENSITIVE ADHESIVES PREPARED FROM DEGRADABLE MONOMERS AND POLYMERS
  申请人：3M INNOVATIVE PROPERTIES COMPANY

  公开号：US20150337179A1

  公开（公告）日：2015-11-26

  Pressure-sensitive adhesives that have good performance characteristics under typical use conditions and that later can be degraded and/or removed readily under basic conditions are provided. More specifically, the pressure-sensitive adhesives contain a copolymeric (meth)acrylic-based elastomeric material prepared from a polymerizable material that contains a (meth)acrylate monomer having both a (meth)acryloyl group plus an ester linkage that is not part of a (meth)acryloyl group.

  提供了在典型使用条件下具有良好性能特征并在碱性条件下可以轻易降解和/或去除的压敏粘合剂。更具体地说，这些压敏粘合剂包含一种共聚的（甲基）丙烯酸基弹性材料，该材料是由一种含有（甲基）丙烯酸酯单体的聚合物材料制备而成，该单体具有（甲基）丙烯酰基和不是（甲基）丙烯酰基的酯键。
• Production of medium chain length poly-3-hydroxy alkanoates in Escherichia coli, and monomers derived therefrom
  申请人：Eidgenössische Technische Hochschule Zürich Institut für Biotechnologie

  公开号：EP0881293A1

  公开（公告）日：1998-12-02

  Production of medium chain length poly-3-hydroxyalkanoates (mcl-PHAs) in Escherichia coli is reported for the first time. To produce PHA in E. coli, a PHA polymerase encoding gene (phaC2) of Pseudomonas oleovorans GPo1 was introduced into various E. coli strains and fatty acid oxidation mutants thereof. Of these, E. coli fadA/B, E. coli fadRfadA or E. coli fadRfadB mutants, which are defective in specific steps of the fatty acid β-oxidation pathway, allowed production of mcl-PHAs from fatty acids ranging from octanoate to octadecanoate. Maximum amounts of about 10% PHA of total cell dry weight (w/w) were found. The predominant monomers found in these PHAs were always the same, independently of the chain length of the supplied fatty acids: 3-hydroxyoctanoate for even chain length fatty acids and a combination of 3-hydroxynonanoate and 3-hydroxyheptanoate for odd chain length fatty acids. Since the monomer composition of the produced polymer was independent of the fatty acid chain length, β-oxidation occurs in these β-oxidation mutants. The polymer may be hydrolyzed to yield interesting optically active monomers and their esters.

  这是首次报道在大肠杆菌中生产中链长度的聚-3-羟基烷酸（cl-PHAs）。为了在大肠杆菌中生产 PHA，我们将油假单胞菌 GPo1 的 PHA 聚合酶编码基因（phaC2）导入各种大肠杆菌菌株及其脂肪酸氧化突变体中。其中，大肠杆菌 fadA/B、大肠杆菌 fadRfadA 或大肠杆菌 fadRfadB 突变体在脂肪酸 β 氧化途径的特定步骤中存在缺陷，可利用从辛酸酯到十八酸酯的脂肪酸生产 mcl-PHA。研究发现，PHA 的最大含量约为细胞总干重的 10%。这些 PHA 中的主要单体始终相同，与所提供脂肪酸的链长无关：偶数链长的脂肪酸为 3-羟基辛酸酯，奇数链长的脂肪酸为 3-羟基壬酸酯和 3-羟基庚酸酯的组合。由于所生产聚合物的单体组成与脂肪酸链长无关，因此在这些 β-氧化突变体中会发生 β-氧化。这种聚合物可通过水解产生有趣的光学活性单体及其酯类。
• Maehlmann, Chemisches Zentralblatt, 1915, vol. 86, # II, p. 1178
  作者：Maehlmann

  DOI：——

  日期：——
• Polyolefin lubricant systems and polymer composites containing such lubricants
  申请人：BEATRICE FOODS CO.

  公开号：EP0124955B1

  公开（公告）日：1988-01-20