2-<2-Oxo-aethyl>-pentansaeure | 89941-66-2

• 分子结构分类: 有机化合物 - 脂质和类脂质分子 - 脂肪酰基
• 英文名称: 2-<2-Oxo-aethyl>-pentansaeure
• 英文别名: (+/-)-4-Oxo-2-propyl-buttersaeure；3-Formyl-2-propyl-propionsaeure；2-(2-Oxoethyl)pentanoic acid
• CAS: 89941-66-2
• 化学式: C₇H₁₂O₃
• mdl: MFCD19229491
• 分子量: 144.17
• InChiKey: PQFDVQSRMGNGTF-UHFFFAOYSA-N

计算性质

• 辛醇/水分配系数(LogP)：
  0.6
• 重原子数：
  10
• 可旋转键数：
  5
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.714
• 拓扑面积：
  54.4
• 氢给体数：
  1
• 氢受体数：
  3

反应信息

• 作为反应物：
  描述：

  2-<2-Oxo-aethyl>-pentansaeure 在 potassium permanganate 作用下， 生成 丙琥珀酸
  参考文献：
  名称：

  Salmon-Legagneur,F.; Le Goff,Y., Bulletin de la Societe Chimique de France, 1965, p. 1761 - 1767

  摘要：

  DOI：
• 作为产物：
  描述：

  opt. inakt. 4-Ethoxy-4-hydroxy-2-propyl-buttersaeure-lacton 在 sodium hydroxide 作用下， 生成 2-<2-Oxo-aethyl>-pentansaeure
  参考文献：
  名称：

  Salmon-Legagneur,F.; Le Goff,Y., Bulletin de la Societe Chimique de France, 1965, p. 1761 - 1767

  摘要：

  DOI：

文献信息

• NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF
  申请人：SU Zhengyu

  公开号：US20160039879A1

  公开（公告）日：2016-02-11

  The present invention relates to a compound of the Formula (I)): or pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same, a method for treating or preventing viral infections, inflammation, dry eye, central nervous disorders, cardiovascular diseases, cancer, obesity, diabetes, muscular dystrophy, and hair loss.

  本发明涉及公式（I）的化合物或其药学上可接受的盐，其中符号如规范中定义；包括该化合物的制药组合物，一种用于治疗或预防病毒感染、炎症、干眼症、中枢神经系统疾病、心血管疾病、癌症、肥胖症、糖尿病、肌肉萎缩症和脱发的方法。
• PROCESS FOR THE RECOVERY OF RHODIUM
  申请人：DSM N.V.

  公开号：EP1301276A1

  公开（公告）日：2003-04-16
• [EN] PROCESS FOR THE PREPARATION OF AN ACETAL<br/>[FR] PROCEDE DE PREPARATION D'UN ACETAL
  申请人：——

  公开号：WO1995006025A1

  公开（公告）日：1995-03-02

  [EN] Process for the preparation of an acetal by hydroformylation of an ethylenically unsaturated organic compound, the ethylenically unsaturated organic compound being contacted with carbon monoxide, hydrogen, an alkanol and a metal-containing catalyst system, the catalyst system comprises: a) platinum or a platinum compound, b) a bidentate ligand with the general formula: R<1>R<2>-M-R-M-R<3>R<4>, where M represents a phosphorus, antimony or arsenic atom, R represents a divalent bridging group having at least three atoms and where R<1>, R<2>, R<3> and R<4> represent the same or different hydrocarbon groups, which may or may not be substituted, c) and a Bronsted acid with a pKa < 2 and/or a Lewis acid.
  [FR] Procédé de préparation d'un acétal par hydroformylation d'un composé organique éthyléniquement insaturé. On met en contact le composé organique éthyléniquement insaturé et du monoxyde de carbone, de l'hydrogène, un alcanol et un système catalyseur renfermant un métal. Ledit système catalyseur comporte (a) du platine ou un composé platiné; (b) un ligand bidenté répondant à la formule générale R<1>R<2>-M-R-M-R<3>R<4>, dans laquelle M représente un atome de phosphore, d'antimoine ou d'arsenic, R représente un groupe bivalent de pontage possédant au moins trois atomes, et R<1>, R<2>, R<3> et R<4> représentent les mêmes groupes hydrocarburés éventuellement substitués ou des groupes hydrocarburés éventuellement substitués différents; et (c) un acide de Brönsted ayant un pKa inférieur à 2, et/ou un acide de Lewis.
• [EN] PROCESS FOR THE RECOVERY OF RHODIUM<br/>[FR] PROCEDE DE RECUPERATION DE RHODIUM
  申请人：DSM NV

  公开号：WO2002005956A1

  公开（公告）日：2002-01-24

  A process for the recovery of rhodium from an organic reaction mixture containing rhodium/phosphite ligand complex, phosphite degradation products and high-boiler organic compounds, wherein A) the organic reaction mixture is subjected to an aqueous oxidative and/or acidic treatment, resulting in an aqueous-polar organic two-phase mixture, B) the aqueous phase is removed, C) solution of lipophilic phosphine and/or lipophilic phosphite in a non-polar solvent is added to the organic phase, which solvent is immiscible with the polar organic phase, resulting in a two-phase mixture containing a non-polar organic phase rich in rhodium and lipophilic phosphine and/or lipophilic phosphite and a polar organic phase rich in phosphite degradation products and high-boiler organic compounds, or the polar organic phase is extracted with an immiscible non-polar organic solvent, resulting in a two-phase mixture containing a non-polar organic phase rich in phosphite degradation products and a polar organic phase rich in rhodium, D) the non-polar organic phase is separated from the polar organic phase.
• [EN] NOVEL CYCLOSPORIN DERIVATIVES AND USES THEREOF<br/>[FR] NOUVEAUX DÉRIVÉS DE CYCLOSPORINE ET LEURS UTILISATIONS
  申请人：SU ZHUANG

  公开号：WO2014145686A2

  公开（公告）日：2014-09-18

  The present invention relates to a compound of the Formula (I)): or pharmaceutically acceptable salt thereof, wherein the symbols are as defined in the specification; a pharmaceutical composition comprising the same, a method for treating or preventing viral infections, inflammation, dry eye, central nervous disorders, cardiovascular diseases, cancer, obesity, diabetes, muscular dystrophy, and hair loss.