4-甲氧基苯甲醛-3-磺酸 | 81349-07-7

• 分子结构分类: 有机化合物 - 苯类化合物 - 苯和取代衍生物
• 中文名称: 4-甲氧基苯甲醛-3-磺酸
• 英文名称: 5-formyl-2-methoxy-benzene sulfonic acid
• 英文别名: Natrium-2-methoxy-5-formyl-phenyl-sulfat；4-methoxybenzaldehyde-3-sulfonic acid；3-sulpho-4-methoxybenzaldehyde；5-Formyl-2-methoxybenzenesulfonic acid
• CAS: 81349-07-7
• 化学式: C₈H₈O₅S
• 分子量: 216.215
• InChiKey: CXANNMZOMWEXTN-UHFFFAOYSA-N

物化性质

• 熔点：
  >350 °C(Solv: methanol (67-56-1))
• 密度：
  1.462±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  0.1
• 重原子数：
  14
• 可旋转键数：
  3
• 环数：
  1.0
• sp3杂化的碳原子比例：
  0.12
• 拓扑面积：
  89
• 氢给体数：
  1
• 氢受体数：
  5

反应信息

• 作为反应物：
  描述：

  苯酞 、 4-甲氧基苯甲醛-3-磺酸 在 sodium methylate 作用下， 以 甲醇 为溶剂， 生成 2-(p-Methoxy-m-sulfonyl-phenyl)-1,3-indandion
  参考文献：
  名称：

  抗炎2-芳基-1,3-茚满二酮。

  摘要：

  DOI：

  10.1021/jm00308a035
• 作为产物：
  描述：

  4-甲氧基苯甲醛 以78%的产率得到
  参考文献：
  名称：

  KATRITZKY, A. R.;YANG, YU-KUN;GABRIELSEN, B.;MARQUET, J., J. CHEM. SOC. PERKIN TRANS., 1984, N 5, 857-866

  摘要：

  DOI：

文献信息

• O-Phenyl Chalcone Compounds And Preparation Method And Use Thereof
  申请人：Sun Yat-Sen University

  公开号：US20160333033A1

  公开（公告）日：2016-11-17

  Disclosed are an o-phenyl chalcone compounds and preparation methods and uses thereof. The o-phenyl chalcone compounds are capable of inhibiting the aggregation of microtubules in tumor cells and influencing the mitosis of the cells, and have a high antitumor activity. The compounds also have inhibitory activity against proliferation on various tumor cells, such as a human ovary cancer cell A2780, a human colon cancer cell HCT8, a human breast cancer cell MCF7, a human lung cancer cell A549, a human colon cancer cell SW480, a human nasopharyngeal carcinoma cell CNE2, a human liver cancer cell HepG2 and the like at nanomole concentrations.

  揭示了一种 o-苯基查尔酮化合物及其制备方法和用途。这些 o-苯基查尔酮化合物能够抑制肿瘤细胞微管的聚集，影响细胞的有丝分裂，并具有较高的抗肿瘤活性。这些化合物还在纳摩尔浓度下对各种肿瘤细胞的增殖具有抑制活性，如人卵巢癌细胞A2780、人结肠癌细胞HCT8、人乳腺癌细胞MCF7、人肺癌细胞A549、人结肠癌细胞SW480、人鼻咽癌细胞CNE2、人肝癌细胞HepG2等。
• Novel colorants, colorant stabilizers, ink compositions, and improved methods of making the same
  申请人：——

  公开号：US20010032565A1

  公开（公告）日：2001-10-25

  The present invention relates to a family of new porphine compounds for use as colorants and/or colorant stabilizers. The new porphine compounds may be used alone or may be used in combination with one or more colorants to provide light stability to colorants. The present invention further relates to inks containing the new porphine compounds and a method for making the new compounds. The present invention also relates to improved methods of making porphines. The improved processes allow the production of porphines at lower cost and higher yields compared to conventional methods of making porphines.

  本发明涉及一类新的卟啉化合物家族，用作染料和/或染料稳定剂。新的卟啉化合物可以单独使用，也可以与一个或多个染料结合使用，以提供对染料的光稳定性。本发明还涉及含有新卟啉化合物的油墨和制备新化合物的方法。本发明还涉及改进的卟啉制备方法。改进的工艺使得卟啉的生产成本更低，产量更高，与传统的卟啉制备方法相比。
• O-PHENYL CHALCONE COMPOUND AND PREPARATION METHOD AND USE THEREOF
  申请人：Sun Yat-Sen University

  公开号：EP3118204A1

  公开（公告）日：2017-01-18

  Disclosed are an o-phenyl chalcone compounds and preparation methods and uses thereof. The o-phenyl chalcone compounds are capable of inhibiting the aggregation of microtubules in tumor cells and influencing the mitosis of the cells, and has a high antitumor activity. The compounds also have inhibitory activity against proliferation on various tumor cells, such as a human ovary cancer cell A2780, a human colon cancer cell HCT8, a human breast cancer cell MCF7, a human lung cancer cell A549, a human colon cancer cell SW480, a human nasopharyngeal carcinoma cell CNE2, a human liver cancer cell HepG2 and the like at nanomole concentrations.

  本发明公开了一种邻苯基查尔酮化合物及其制备方法和用途。邻苯基查尔酮化合物能够抑制肿瘤细胞中微管的聚集，影响细胞的有丝分裂，具有很高的抗肿瘤活性。这些化合物还具有抑制各种肿瘤细胞增殖的活性，如纳摩尔浓度下的人卵巢癌细胞 A2780、人结肠癌细胞 HCT8、人乳腺癌细胞 MCF7、人肺癌细胞 A549、人结肠癌细胞 SW480、人鼻咽癌细胞 CNE2、人肝癌细胞 HepG2 等。
• Flammwidrige Polycarbonatformmassen
  申请人：BAYER AG

  公开号：EP0531861B1

  公开（公告）日：1996-01-31
• DICYCLIC METAL COMPLEX FORMAZAN DERIVATIVES, PROCESS FOR PRODUCING THE SAME, COMPOSITION CONTAINING THE SAME AND DYEING PROCESS EMPLOYING THE SAME
  申请人：Kyungin Synthetic Corporation

  公开号：EP0777703B1

  公开（公告）日：2003-06-25