Bromothioacetate de 2-F-hexylethyle | 132711-07-0

• 分子结构分类: 有机化合物 - 有机酸及其衍生物 - 硫代羧酸及其衍生物
• 英文名称: Bromothioacetate de 2-F-hexylethyle
• 英文别名: S-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluorooctyl) 2-bromoethanethioate
• CAS: 132711-07-0
• 化学式: C₁₀H₆BrF₁₃OS
• 分子量: 501.106
• InChiKey: HPUYBMAMRAAOMX-UHFFFAOYSA-N

物化性质

• 沸点：
  90 °C(Press: 0.998 Torr)
• 密度：
  1.734±0.06 g/cm3(Predicted)

计算性质

• 辛醇/水分配系数(LogP)：
  5.77
• 重原子数：
  26.0
• 可旋转键数：
  8.0
• 环数：
  0.0
• sp3杂化的碳原子比例：
  0.9
• 拓扑面积：
  17.07
• 氢给体数：
  0.0
• 氢受体数：
  2.0

反应信息

• 作为反应物：
  描述：

  Bromothioacetate de 2-F-hexylethyle 、 三乙胺 以 乙醚 为溶剂， 以90%的产率得到Triethyl-(3,3,4,4,5,5,6,6,7,7,8,8,8-tridecafluoro-octylsulfanylcarbonylmethyl)-ammonium; bromide
  参考文献：
  名称：

  Synthése de nouveaux intermédiaires F-alkyles précurseurs de tensioactifs cationiques hautement fluorés

  摘要：

  The syntheses of F-alkyl compounds such as(~)[GRAPHICS](~)(where R(F) = C4F9, C6F13, C8F17 and Q = S, O, NH) by the reaction of bromoacetyl bromide with an F-alkyl compound such as RFC2H4QH are reported. These compounds show high reactivity with nucelophilic substrates. They are intended for use as precursors of surfactants or as precursors of monomers for the elaboration of artificial vesicles.

  DOI：

  10.1016/s0022-1139(00)80210-9
• 作为产物：
  描述：

  3,3,4,4,5,5,6,6,7,7,8,8,8-十三氟-1-辛硫醇 、 溴乙酰溴 以 乙醚 为溶剂， 反应 12.0h， 以78%的产率得到Bromothioacetate de 2-F-hexylethyle
  参考文献：
  名称：

  Synthése de nouveaux intermédiaires F-alkyles précurseurs de tensioactifs cationiques hautement fluorés

  摘要：

  The syntheses of F-alkyl compounds such as(~)[GRAPHICS](~)(where R(F) = C4F9, C6F13, C8F17 and Q = S, O, NH) by the reaction of bromoacetyl bromide with an F-alkyl compound such as RFC2H4QH are reported. These compounds show high reactivity with nucelophilic substrates. They are intended for use as precursors of surfactants or as precursors of monomers for the elaboration of artificial vesicles.

  DOI：

  10.1016/s0022-1139(00)80210-9

文献信息

• Obtention d'isothiocyanates polyfluoroalkylés par réaction d'isomérisation: leurs réactions sur les amines
  作者：H. Trabelsi、M.A. Jouani、A. Cambon

  DOI：10.1016/0022-1139(96)03473-2

  日期：1996.7

  New polyfluoroalkylated isothiocyanates have been synthesized. They are obtained by isomerisation in satisfactory yields. Condensation of these compounds with diamines is reported.

  已经合成了新的多氟烷基化的异硫氰酸酯。它们通过异构化以令人满意的产率获得。报道了这些化合物与二胺的缩合。
• Préparation de nouveaux β-aminoacides a longue chaine et leur conversion en carboxybetaı̈nes bicatenaires F-alkylées
  作者：D Enjalbert、C Bassilana、V Krier、S Szönyi、A Cambon

  DOI：10.1016/s0022-1139(98)00277-2

  日期：1999.2

  The synthesis of amphoteric F-alkylated bitailed surfactants derived from new β-aminoacid intermediates is described. N-alkyl N-benzyl amines or N-alkyl N-methyl amines are added to acrylic acid. The β-amino acids obtained are quaternized by 2-F-alkyl ethyl acetates or thioacetate bromides to produce the F-alkylated double-chain carboxybetaı̈nes.

  描述了衍生自新的β-氨基酸中间体的两性F-烷基化的巴比妥表面活性剂的合成。将N-烷基N-苄基胺或N-烷基N-甲基胺加到丙烯酸中。得到的β-氨基酸被2-F-烷基乙酸乙酯或硫代乙酸溴化物季铵化，生成F-烷基化的双链羧基甜菜碱。
• Preparation and antimicrobial behaviour of gemini fluorosurfactants
  作者：Lionel Massi、Frédéric Guittard、Richard Levy、Yves Duccini、Serge Géribaldi

  DOI：10.1016/s0223-5234(03)00059-x

  日期：2003.5

  The introduction of perfluorinated chains in the molecular structure of quaternary ammonium gemini surfactants have led to particularly active antimicrobial agents evaluated in this work. Connectors and spacers were studied in relation with antimicrobial activity in order to determine which molecular parameters are 'critical' for biological activity. (C) 2003 Editions scientifiques et medicales Elsevier SAS. All rights reserved.
• Synthèse de 3-[2F-alkyléthylamino]-1,2-époxypropanes et obtention de nouveaux tensioactifs mono ou bicaténaires à tête β-hydroxylée
  作者：P.S. Abenin、F. Szönyi、A. Cambon

  DOI：10.1016/s0022-1139(00)81248-8

  日期：1991.11

  In this paper we report the synthesis of new intermediates of the type 3-[2-F-alkyl-ethylamino]-1,2-epoxypropanes which lead simply and with good yields to a large range of fluorinated monotailed, bitailed and hydrogenated/fluorinated bitailed surfactants having a secondary amino group and at least one hydroxy group. Evaluation of their surface properties has allowed the contribution of each hydrophobic tail contained in the hydrogenated and fluorinated bitailed molecules to be demonstrated.
• ALAIN, SISMONDI;ABENIN, PARFAIT;CAMBON, AIME
  作者：ALAIN, SISMONDI、ABENIN, PARFAIT、CAMBON, AIME

  DOI：——

  日期：——