4-chloro-3-[(2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonyl)-amino]-benzoic acid methyl ester | 1386979-05-0

分子结构分类

有机化合物 - 苯类化合物 - 苯和取代衍生物

中文名称

——

中文别名

——

英文名称

4-chloro-3-[(2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonyl)-amino]-benzoic acid methyl ester

英文别名

4-chloro-3-[(2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonyl)amino]benzoic acid methyl ester；Methyl 4-Chloro-3-{[(2-Methoxy-7-Oxo-7,8-Dihydropyrido[2,3-D]pyrimidin-6-Yl)carbonyl]amino}benzoate；methyl 4-chloro-3-[(2-methoxy-7-oxo-8H-pyrido[2,3-d]pyrimidine-6-carbonyl)amino]benzoate

4-chloro-3-[(2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonyl)-amino]-benzoic acid methyl ester化学式

CAS

1386979-05-0

化学式

C₁₇H₁₃ClN₄O₅

mdl

——

分子量

388.767

InChiKey

SIVLENRHVVVPKJ-UHFFFAOYSA-N

BEILSTEIN

——

EINECS

——

计算性质

辛醇/水分配系数(LogP)：

1.8
重原子数：

27
可旋转键数：

5
环数：

3.0
sp3杂化的碳原子比例：

0.12
拓扑面积：

120
氢给体数：

2
氢受体数：

7

上下游信息

上游原料

中文名称	英文名称	CAS号	化学式	分子量
——	Methyl 2-methoxy-7-oxo-7,8-dihydropyrido[2,3-D]pyrimidine-6-carboxylate	209849-69-4	C₁₀H₉N₃O₄	235.199

下游产品

中文名称	英文名称	CAS号	化学式	分子量
——	4-chloro-3-[(2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonyl)-amino]-benzoic acid	1386980-75-1	C₁₆H₁₁ClN₄O₅	374.74
——	4-chloro-3-[(2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonyl)-amino]-benzoic acid 4-chloro-benzyl ester	1386979-52-7	C₂₃H₁₆Cl₂N₄O₅	499.31
——	4-chloro-3-[(2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonyl)-amino]-benzoic acid benzyl ester	1386979-51-6	C₂₃H₁₇ClN₄O₅	464.865
——	4-chloro-3-[(2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonyl)-amino]-benzoic acid 3-chloro-benzyl ester	1386979-54-9	C₂₃H₁₆Cl₂N₄O₅	499.31
——	4-chloro-3-[(2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carbonyl)-amino]-benzoic acid 2-chloro-benzyl ester	1386979-53-8	C₂₃H₁₆Cl₂N₄O₅	499.31
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid (5-carbamoyl-2-chloro-phenyl)-amide	1386979-83-4	C₁₆H₁₂ClN₅O₄	373.755
——	2-Methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid (2-chloro-5-phenylcarbamoyl-phenyl)-amide	1386979-50-5	C₂₂H₁₆ClN₅O₄	449.853
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid (2-chloro-5-methylcarbamoyl-phenyl)-amide	1386979-74-3	C₁₇H₁₄ClN₅O₄	387.782
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid [2-chloro-5-(4-chloro-benzylcarbamoyl)-phenyl]-amide	1386979-47-0	C₂₃H₁₇Cl₂N₅O₄	498.325
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid {2-chloro-5-[(pyridin-4-ylmethyl)-carbamoyl]-phenyl}-amide	1386979-67-4	C₂₂H₁₇ClN₆O₄	464.868
——	N-(5-(3-aminopropylcarbamoyl)-2-chlorophenyl)-2-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide	1386980-37-5	C₁₉H₁₉ClN₆O₄	430.851
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid (2-chloro-5-isobutylcarbamoyl-phenyl)-amide	1386979-75-4	C₂₀H₂₀ClN₅O₄	429.863
N-[2-氯-5-[[[[((3-氯苯基)甲基]氨基]羰基]苯基]-7,8-二氢-2-甲氧基-7-氧代吡啶并[2,3-d]嘧啶-6-羧酰胺	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid [2-chloro-5-(3-chloro-benzylcarbamoyl)-phenyl]-amide	1386979-55-0	C₂₃H₁₇Cl₂N₅O₄	498.325
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid {2-chloro-5-[(pyridin-3-ylmethyl)-carbamoyl]-phenyl}-amide	1386979-66-3	C₂₂H₁₇ClN₆O₄	464.868
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid (2-chloro-5-phenethylcarbamoyl-phenyl)-amide	1386979-68-5	C₂₄H₂₀ClN₅O₄	477.907
——	N-(5-(3-amino-3-oxopropylcarbamoyl)-2-chlorophenyl)-2-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide	1386980-39-7	C₁₉H₁₇ClN₆O₅	444.834
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid [5-(benzyl-methyl-carbamoyl)-2-chloro-phenyl]-amide	1386979-60-7	C₂₄H₂₀ClN₅O₄	477.907
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid {2-chloro-5-[2-(3-chloro-phenyl)-ethylcarbamoyl]-phenyl}-amide	1386979-69-6	C₂₄H₁₉Cl₂N₅O₄	512.352
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid [2-chloro-5-(2-chloro-benzylcarbamoyl)-phenyl]-amide	1386979-48-1	C₂₃H₁₇Cl₂N₅O₄	498.325
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid {2-chloro-5-[(3-chloro-benzyl)-methyl-carbamoyl]-phenyl}-amide	1386979-64-1	C₂₄H₁₉Cl₂N₅O₄	512.352
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid {2-chloro-5-[(thiophen-3-ylmethyl)-carbamoyl]-phenyl}-amide	1386979-58-3	C₂₁H₁₆ClN₅O₄S	469.908
——	2-Methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid [2-chloro-5-(3-trifluoromethyl-benzylcarbamoyl)-phenyl]-amide	1386979-59-4	C₂₄H₁₇ClF₃N₅O₄	531.878
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid {2-chloro-5-[(pyridin-2-ylmethyl)-carbamoyl]-phenyl}-amide	1386979-65-2	C₂₂H₁₇ClN₆O₄	464.868
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid [5-(2-amino-1-phenyl-ethylcarbamoyl)-2-chloro-phenyl]-amide	1386979-70-9	C₂₄H₂₁ClN₆O₄	492.922
——	(S)-N-(5-(2-amino-1-phenylethylcarbamoyl)-2-chlorophenyl)-2-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide	1386980-12-6	C₂₄H₂₁ClN₆O₄	492.922
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid {2-chloro-5-[(thiophen-2-ylmethyl)-carbamoyl]-phenyl}-amide	1386979-57-2	C₂₁H₁₆ClN₅O₄S	469.908
——	2-Methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid {5-[2-amino-1-(3-chloro-phenyl)-ethylcarbamoyl]-2-chloro-phenyl}-amide	1386979-80-1	C₂₄H₂₀Cl₂N₆O₄	527.367
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid {5-[(S)-2-amino-1-(3-chloro-phenyl)ethylcarbamoyl]-2-chloro-phenyl}amide	1386980-14-8	C₂₄H₂₀Cl₂N₆O₄	527.367
——	(R)-N-(5-(2-amino-1-(3-chlorophenyl)ethylcarbamoyl)-2-chlorophenyl)-2-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide	1386980-13-7	C₂₄H₂₀Cl₂N₆O₄	527.367
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid [5-(3-amino-1-phenyl-propylcarbamoyl)-2-chloro-phenyl]-amide	1386979-73-2	C₂₅H₂₃ClN₆O₄	506.948
——	(S)-N-(5-(3-amino-1-phenylpropylcarbamoyl)-2-chlorophenyl)-2-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide	1386980-49-9	C₂₅H₂₃ClN₆O₄	506.948
——	(R)-N-(5-(3-Amino-1-phenylpropylcarbamoyl)-2-chlorophenyl)-2-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide	1386980-45-5	C₂₅H₂₃ClN₆O₄	506.948
——	N-(5-(4-Amino-1-phenylbutylcarbamoyl)-2-chlorophenyl)-2-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide	1386980-59-1	C₂₆H₂₅ClN₆O₄	520.975
——	N-(5-(5-amino-1-phenylpentylcarbamoyl)-2-chlorophenyl)-2-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide	1386980-57-9	C₂₇H₂₇ClN₆O₄	535.002
——	2-methoxy-7-oxo-7,8-dihydro-pyrido[2,3-d]pyrimidine-6-carboxylic acid {5-[3-amino-1-(3-chloro-phenyl)-propylcarbamoyl]-2-chloro-phenyl}-amide	1386979-79-8	C₂₅H₂₂Cl₂N₆O₄	541.393
——	(S)-N-(5-(3-amino-1-(3-chlorophenyl)propylcarbamo-yl)-2-chlorophenyl)-2-methoxy-7-oxo-7,8-dihydropyrido[2,3-d]pyrimidine-6-carboxamide	1386980-15-9	C₂₅H₂₂Cl₂N₆O₄	541.393